CONDENSED CONSOLIDATED STATEMENTS OF CASH FLOWS - USD ($) $ in Thousands	6 Months Ended
	Jun. 30, 2024	Jun. 30, 2023
Cash flows from operating activities
Net loss	$ (10,027)	$ (37,698)
Adjustments to reconcile net loss to net cash used in operating activities
Depreciation and amortization	9,690	1,436
Net amortization of premiums and discounts on short-term investments	(6,331)	(5,599)
Share-based compensation expense	14,323	21,735
Foreign exchange on finance lease liability	(5,705)	417
Other, net	275	(3,652)
Net changes in operating assets and liabilities
Accounts receivable, net	(1,433)	(6,016)
Inventories, net	852	(8,403)
Prepaid expenses and other current assets	(4,305)	2,374
Non-current operating assets	(12)	(16)
Accounts payable, accrued and other liabilities	283	1,245
Operating lease liabilities	(365)	(319)
Net cash used in operating activities	(2,755)	(34,496)
Cash flows from investing activities
Purchase of investments	(318,126)	(256,439)
Proceeds from investments	328,877	288,291
Upfront lease payment	(44)	(11,864)
Purchase of property and equipment	0	(524)
Capitalized patent costs	(96)	(212)
Net cash provided by investing activities	10,611	19,252
Cash flows from financing activities
Repurchase of common shares	(18,435)	0
Principal portion of finance lease payments	(6,001)	0
Proceeds from exercise of stock options and employee share purchase plan	1,112	2,779
Cash (used in) provided by financing activities	(23,324)	2,779
Net decrease in cash, cash equivalents and restricted cash	(15,468)	(12,465)
Cash, cash equivalents and restricted cash, beginning of period	48,875	94,172
Cash, cash equivalents and restricted cash, end of period	33,407	81,707
Supplemental cash flow information
Cash received for interest	2,132	2,713
Cash paid for income taxes	(1,459)	(277)
Reconciliation of cash, cash equivalents and restricted cash to the condensed consolidated balance sheets
Cash, cash equivalents	33,265	81,389
Restricted cash	142	318
Total cash, cash equivalents and restricted cash	$ 33,407	$ 81,707