The Securities and Exchange Commission has not necessarily reviewed the information in this filing and has not determined if it is accurate and complete.
The reader should not assume that the information is accurate and complete.

UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
FORM 13F

FORM 13F INFORMATION TABLE
OMB APPROVAL
OMB Number: 3235-0006
Estimated average burden
hours per response: 23.8
COLUMN 1 COLUMN 2 COLUMN 3 COLUMN 4 COLUMN 5 COLUMN 6 COLUMN 7 COLUMN 8
VALUE SHRS OR SH/ PUT/ INVESTMENT OTHER VOTING AUTHORITY
NAME OF ISSUER TITLE OF CLASS CUSIP (x$1000) PRN AMT PRN CALL DISCRETION MANAGER SOLE SHARED NONE
ACHILLION PHARMACEUTICALS IN COM 00448Q201 1,079 100,000 SH   SOLE   100,000 0 0
ADAMAS PHARMACEUTICALS INC COM 00548A106 2,266 80,000 SH   SOLE   80,000 0 0
AGIOS PHARMACEUTICALS INC COM 00847X104 2,207 34,000 SH   SOLE   34,000 0 0
ALEXION PHARMACEUTICALS INC COM 015351109 6,289 32,969 SH   SOLE   32,969 0 0
ALKERMES PLC SHS G01767105 6,939 87,415 SH   SOLE   87,415 0 0
ALNYLAM PHARMACEUTICALS INC COM 02043Q107 4,728 50,222 SH   SOLE   50,222 0 0
AMGEN INC COM 031162100 5,807 35,773 SH   SOLE   35,773 0 0
ASTRAZENECA PLC SPONSORED ADR 046353108 1,667 49,100 SH   SOLE   49,100 0 0
AXOVANT SCIENCES LTD COM G0750W104 340 18,852 SH   SOLE   18,852 0 0
BIOCRYST PHARMACEUTICALS COM 09058V103 1,032 100,000 SH   SOLE   100,000 0 0
BIOGEN INC COM 09062X103 3,211 10,482 SH   SOLE   10,482 0 0
BIOMARIN PHARMACEUTICAL INC COM 09061G101 4,596 43,870 SH   SOLE   43,870 0 0
BRISTOL MYERS SQUIBB CO COM 110122108 5,304 77,100 SH   SOLE   77,100 0 0
NOVAVAX INC COM 670002104 839 100,000 SH Call SOLE   100,000 0 0
CARBYLAN THERAPEUTICS INC COM 141384107 63 17,500 SH   SOLE   17,500 0 0
CELGENE CORP COM 151020104 5,743 47,956 SH   SOLE   47,956 0 0
CLOVIS ONCOLOGY INC COM 189464100 1,750 50,000 SH   SOLE   50,000 0 0
DICERNA PHARMACEUTICALS INC COM 253031108 1,187 100,000 SH   SOLE   100,000 0 0
DIPEXIUM PHARMACEUTICALS INC COM 25456J104 280 25,000 SH   SOLE   25,000 0 0
EPIZYME INC COM 29428V104 2,173 135,627 SH   SOLE   135,627 0 0
FLAMEL TECHNOLOGIES SA SPONSORED ADR 338488109 693 56,788 SH   SOLE   56,788 0 0
FLUIDIGM CORP DEL COM 34385P108 757 70,000 SH   SOLE   70,000 0 0
GILEAD SCIENCES INC COM 375558103 3,410 33,700 SH   SOLE   33,700 0 0
HOLOGIC INC COM 436440101 1,857 48,000 SH   SOLE   48,000 0 0
IGNYTA INC COM 451731103 1,340 100,000 SH   SOLE   100,000 0 0
ILLUMINA INC COM 452327109 4,346 22,643 SH   SOLE   22,643 0 0
INCYTE CORP COM 45337C102 5,210 48,045 SH   SOLE   48,045 0 0
INFINITY PHARMACEUTICALS INC COM 45665G303 236 30,000 SH   SOLE   30,000 0 0
IONIS PHARMACEUTICALS INC COM 462222100 6,345 102,459 SH   SOLE   102,459 0 0
ISHARES TR NASDQ BIOTEC ETF 464287556 10,691 31,600 SH   SOLE   31,600 0 0
KARYOPHARM THERAPEUTICS INC COM 48576U106 795 60,000 SH   SOLE   60,000 0 0
LOXO ONCOLOGY INC COM 548862101 1,707 60,000 SH   SOLE   60,000 0 0
MACROGENICS INC COM 556099109 929 30,000 SH   SOLE   30,000 0 0
MEDICINES CO COM 584688105 934 25,000 SH   SOLE   25,000 0 0
MEDIVATION INC COM 58501N101 4,414 91,310 SH   SOLE   91,310 0 0
MERCK & CO INC NEW COM 58933Y105 4,754 90,000 SH   SOLE   90,000 0 0
MERRIMACK PHARMACEUTICALS IN COM 590328100 968 122,500 SH   SOLE   122,500 0 0
METTLER TOLEDO INTERNATIONAL COM 592688105 3,290 9,700 SH   SOLE   9,700 0 0
NANOSTRING TECHNOLOGIES INC COM 63009R109 1,503 102,200 SH   SOLE   102,200 0 0
NEKTAR THERAPEUTICS COM 640268108 5,874 348,583 SH   SOLE   348,583 0 0
OPHTHOTECH CORP COM 683745103 1,335 17,000 SH   SOLE   17,000 0 0
PACIRA PHARMACEUTICALS INC COM 695127100 1,467 19,110 SH   SOLE   19,110 0 0
PARATEK PHARMACEUTICALS INC COM 699374302 1,138 60,000 SH   SOLE   60,000 0 0
PRONAI THERAPEUTICS INC COM 74346L101 451 30,000 SH   SOLE   30,000 0 0
PROSHARES TR PSHS ULT NASB 74347R214 1,067 14,919 SH   SOLE   14,919 0 0
NOVAVAX INC COM 670002104 839 100,000 SH Put SOLE   100,000 0 0
QIAGEN NV REG SHS N72482107 4,424 160,000 SH   SOLE   160,000 0 0
REGENERON PHARMACEUTICALS COM 75886F107 5,816 10,714 SH   SOLE   10,714 0 0
SEATTLE GENETICS INC COM 812578102 5,704 127,088 SH   SOLE   127,088 0 0
SERES THERAPEUTICS INC COM 81750R102 1,158 33,000 SH   SOLE   33,000 0 0
TOKAI PHARMACEUTICALS INC COM 88907J107 541 62,007 SH   SOLE   62,007 0 0
UNITED THERAPEUTICS CORP DEL COM 91307C102 1,020 6,514 SH   SOLE   6,514 0 0
VERICEL CORP COM 92346J108 857 332,157 SH   SOLE   332,157 0 0
VERTEX PHARMACEUTICALS INC COM 92532F100 5,242 41,662 SH   SOLE   41,662 0 0
REPROS THERAPEUTICS INC *W EXP 02/08/201 76028H126 33 98,000 SH Call SOLE   98,000 0 0
XENCOR INC COM 98401F105 1,316 90,000 SH   SOLE   90,000 0 0
ZOGENIX INC COM NEW 98978L204 1,411 95,700 SH   SOLE   95,700 0 0