The Securities and Exchange Commission has not necessarily reviewed the information in this filing and has not determined if it is accurate and complete.
The reader should not assume that the information is accurate and complete.

UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
FORM 13F

FORM 13F INFORMATION TABLE
OMB APPROVAL
OMB Number: 3235-0006
Estimated average burden
hours per response: 23.8
COLUMN 1 COLUMN 2 COLUMN 3 COLUMN 4 COLUMN 5 COLUMN 6 COLUMN 7 COLUMN 8
VALUE SHRS OR SH/ PUT/ INVESTMENT OTHER VOTING AUTHORITY
NAME OF ISSUER TITLE OF CLASS CUSIP (x$1000) PRN AMT PRN CALL DISCRETION MANAGER SOLE SHARED NONE
BLUEPRINT MEDICINES CORP COM 09627Y109 195,842 7,393,059 SH   DFND   7,393,059 0 0
ELEVEN BIOTHERAPEUTICS INC COM 286221106 13,653 4,841,591 SH   DFND   4,841,591 0 0
SAGE THERAPEUTICS INC COM 78667J108 640,434 8,773,073 SH   DFND   8,773,073 0 0
ZAFGEN INC COM 98885E103 110,887 3,202,045 SH   DFND   3,202,045 0 0