X0306 4 2018-05-23 0 0001423824 ALDER BIOPHARMACEUTICALS INC ALDR 0001600041 Carter Paul Rutherford C/O ALDER BIOPHARMACEUTICALS, INC. 11804 NORTH CREEK PARKWAY SOUTH BOTHELL WA 98011 1 0 0 0 Stock Option (Right to Buy) 15.50 2018-05-23 4 A 0 15000 0.00 A 2028-05-22 Common Stock 15000 15000 D The shares subject to this option shall fully vest and become exercisable on the date of the 2019 Annual Meeting of the Stockholders of the Issuer, so long as the Reporting Person provides continuous service to the Issuer through such date. /s/ Paul Rutherford Carter 2018-05-25