The Securities and Exchange Commission has not necessarily reviewed the information in this filing and has not determined if it is accurate and complete.
The reader should not assume that the information is accurate and complete.

UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
FORM 13F

FORM 13F INFORMATION TABLE
OMB APPROVAL
OMB Number: 3235-0006
Estimated average burden
hours per response: 23.8
COLUMN 1 COLUMN 2 COLUMN 3 COLUMN 4 COLUMN 5 COLUMN 6 COLUMN 7 COLUMN 8
VALUE SHRS OR SH/ PUT/ INVESTMENT OTHER VOTING AUTHORITY
NAME OF ISSUER TITLE OF CLASS CUSIP (x$1000) PRN AMT PRN CALL DISCRETION MANAGER SOLE SHARED NONE
2U INC COM 90214J101 1,421 25,357 SH   SOLE   25,357 0 0
2U INC COM 90214J101 3,107 55,448 SH   DFND 1 55,448 0 0
ABBVIE INC COM 00287Y109 3,661 41,200 SH Call DFND 1 41,200 0 0
ABBVIE INC COM 00287Y109 1,671 18,800 SH Call SOLE   18,800 0 0
ACADIA HEALTHCARE COMPANY IN COM 00404A109 1,934 40,484 SH   DFND 1 40,484 0 0
ACADIA HEALTHCARE COMPANY IN COM 00404A109 884 18,516 SH   SOLE   18,516 0 0
ACTIVISION BLIZZARD INC COM 00507V109 3,497 54,208 SH   DFND 1 54,208 0 0
ACTIVISION BLIZZARD INC COM 00507V109 1,599 24,792 SH   SOLE   24,792 0 0
AERIE PHARMACEUTICALS INC COM 00771V108 1,901 39,106 SH   DFND 1 39,106 0 0
AERIE PHARMACEUTICALS INC COM 00771V108 870 17,894 SH   SOLE   17,894 0 0
AKCEA THERAPEUTICS INC COM 00972L107 782 28,246 SH   SOLE   28,246 0 0
AKCEA THERAPEUTICS INC COM 00972L107 1,709 61,754 SH   DFND 1 61,754 0 0
ALBEMARLE CORP COM 012653101 2,712 19,899 SH   DFND 1 19,899 0 0
ALBEMARLE CORP COM 012653101 1,241 9,101 SH   SOLE   9,101 0 0
ALIGN TECHNOLOGY INC COM 016255101 8,947 48,031 SH   DFND 1 48,031 0 0
ALIGN TECHNOLOGY INC COM 016255101 4,092 21,969 SH   SOLE   21,969 0 0
ALKERMES PLC SHS G01767105 732 14,406 SH   DFND 1 14,406 0 0
ALKERMES PLC SHS G01767105 335 6,594 SH   SOLE   6,594 0 0
ALNYLAM PHARMACEUTICALS INC COM 02043Q107 2,015 17,154 SH   DFND 1 17,154 0 0
ALNYLAM PHARMACEUTICALS INC COM 02043Q107 922 7,846 SH   SOLE   7,846 0 0
AMAZON COM INC COM 023135106 2,375 2,470 SH   DFND 1 2,470 0 0
AMAZON COM INC COM 023135106 1,086 1,130 SH   SOLE   1,130 0 0
AMERICAN AIRLS GROUP INC COM 02376R102 2,933 61,754 SH   DFND 1 61,754 0 0
AMERICAN AIRLS GROUP INC COM 02376R102 1,341 28,246 SH   SOLE   28,246 0 0
AMERICAN AIRLS GROUP INC COM 02376R102 2,674 56,300 SH Call DFND 1 56,300 0 0
AMERICAN AIRLS GROUP INC COM 02376R102 1,221 25,700 SH Call SOLE   25,700 0 0
ARENA PHARMACEUTICALS INC COM NEW 040047607 2,135 83,709 SH   DFND 1 83,709 0 0
ARENA PHARMACEUTICALS INC COM NEW 040047607 976 38,291 SH   SOLE   38,291 0 0
ARISTA NETWORKS INC COM 040413106 2,602 13,723 SH   DFND 1 13,723 0 0
ARISTA NETWORKS INC COM 040413106 1,190 6,277 SH   SOLE   6,277 0 0
ATLASSIAN CORP PLC CL A G06242104 1,357 38,602 SH   SOLE   38,602 0 0
ATLASSIAN CORP PLC CL A G06242104 2,967 84,398 SH   DFND 1 84,398 0 0
AUTODESK INC COM 052769106 5,546 49,402 SH   DFND 1 49,402 0 0
AUTODESK INC COM 052769106 2,537 22,598 SH   SOLE   22,598 0 0
AVEXIS INC COM 05366U100 2,721 28,129 SH   DFND 1 28,129 0 0
AVEXIS INC COM 05366U100 1,245 12,871 SH   SOLE   12,871 0 0
AXOVANT SCIENCES LTD COM G0750W104 120 17,500 SH Call DFND 1 17,500 0 0
AXOVANT SCIENCES LTD COM G0750W104 54 7,900 SH Call SOLE   7,900 0 0
BAIDU INC SPON ADR REP A 056752108 2,549 10,292 SH   DFND 1 10,292 0 0
BAIDU INC SPON ADR REP A 056752108 1,166 4,708 SH   SOLE   4,708 0 0
BLUEBIRD BIO INC COM 09609G100 754 5,489 SH   DFND 1 5,489 0 0
BLUEBIRD BIO INC COM 09609G100 345 2,511 SH   SOLE   2,511 0 0
BRISTOL MYERS SQUIBB CO COM 110122108 2,186 34,300 SH Call DFND 1 34,300 0 0
BRISTOL MYERS SQUIBB CO COM 110122108 1,001 15,700 SH Call SOLE   15,700 0 0
CALITHERA BIOSCIENCES INC COM 13089P101 2,535 160,979 SH   DFND 1 160,979 0 0
CALITHERA BIOSCIENCES INC COM 13089P101 1,160 73,624 SH   SOLE   73,624 0 0
CATALENT INC COM 148806102 3,670 91,946 SH   DFND 1 91,946 0 0
CATALENT INC COM 148806102 1,679 42,054 SH   SOLE   42,054 0 0
CENTENE CORP DEL COM 15135B101 1,492 15,413 SH   DFND 1 15,413 0 0
CENTENE CORP DEL COM 15135B101 682 7,050 SH   SOLE   7,050 0 0
COGNEX CORP COM 192422103 1,211 10,984 SH   SOLE   10,984 0 0
COGNEX CORP COM 192422103 2,648 24,016 SH   DFND 1 24,016 0 0
DBV TECHNOLOGIES S A SPONSORED ADR 23306J101 582 13,723 SH   DFND 1 13,723 0 0
DBV TECHNOLOGIES S A SPONSORED ADR 23306J101 266 6,277 SH   SOLE   6,277 0 0
ESPERION THERAPEUTICS INC NE COM 29664W105 471 9,401 SH   DFND 1 9,401 0 0
ESPERION THERAPEUTICS INC NE COM 29664W105 215 4,299 SH   SOLE   4,299 0 0
EXACT SCIENCES CORP COM 30063P105 2,910 61,747 SH   DFND 1 61,747 0 0
EXACT SCIENCES CORP COM 30063P105 1,331 28,253 SH   SOLE   28,253 0 0
EXELIXIS INC COM 30161Q104 831 34,307 SH   DFND 1 34,307 0 0
EXELIXIS INC COM 30161Q104 380 15,693 SH   SOLE   15,693 0 0
FACEBOOK INC CL A 30303M102 5,864 34,317 SH   DFND 1 34,317 0 0
FACEBOOK INC CL A 30303M102 2,680 15,683 SH   SOLE   15,683 0 0
FLOOR & DECOR HLDGS INC CL A 339750101 2,137 54,892 SH   DFND 1 54,892 0 0
FLOOR & DECOR HLDGS INC CL A 339750101 977 25,108 SH   SOLE   25,108 0 0
GALAPAGOS NV SPON ADR 36315X101 3,214 31,569 SH   DFND 1 31,569 0 0
GALAPAGOS NV SPON ADR 36315X101 1,469 14,431 SH   SOLE   14,431 0 0
GIGAMON INC COM 37518B102 2,111 50,089 SH   DFND 1 50,089 0 0
GIGAMON INC COM 37518B102 966 22,911 SH   SOLE   22,911 0 0
GW PHARMACEUTICALS PLC ADS 36197T103 2,263 22,298 SH   DFND 1 22,298 0 0
GW PHARMACEUTICALS PLC ADS 36197T103 1,035 10,202 SH   SOLE   10,202 0 0
HCA HEALTHCARE INC COM 40412C101 1,496 18,800 SH Put SOLE   18,800 0 0
HCA HEALTHCARE INC COM 40412C101 3,279 41,200 SH Put DFND 1 41,200 0 0
HDFC BANK LTD ADR REPS 3 SHS 40415F101 2,116 21,957 SH   DFND 1 21,957 0 0
HDFC BANK LTD ADR REPS 3 SHS 40415F101 968 10,043 SH   SOLE   10,043 0 0
HERON THERAPEUTICS INC COM 427746102 997 61,747 SH   DFND 1 61,747 0 0
HERON THERAPEUTICS INC COM 427746102 456 28,253 SH   SOLE   28,253 0 0
ICU MED INC COM 44930G107 2,040 10,979 SH   DFND 1 10,979 0 0
ICU MED INC COM 44930G107 933 5,021 SH   SOLE   5,021 0 0
IMMUNOMEDICS INC COM 452907108 592 42,367 SH   SOLE   42,367 0 0
IMMUNOMEDICS INC COM 452907108 1,295 92,633 SH   DFND 1 92,633 0 0
INOGEN INC COM 45780L104 3,197 33,615 SH   DFND 1 33,615 0 0
INOGEN INC COM 45780L104 1,458 15,331 SH   SOLE   15,331 0 0
INTUITIVE SURGICAL INC COM NEW 46120E602 5,382 15,438 SH   DFND 1 15,438 0 0
INTUITIVE SURGICAL INC COM NEW 46120E602 2,462 7,062 SH   SOLE   7,062 0 0
IRHYTHM TECHNOLOGIES INC COM 450056106 2,189 42,199 SH   DFND 1 42,199 0 0
IRHYTHM TECHNOLOGIES INC COM 450056106 1,001 19,301 SH   SOLE   19,301 0 0
JAZZ PHARMACEUTICALS PLC SHS USD G50871105 666 4,551 SH   SOLE   4,551 0 0
JAZZ PHARMACEUTICALS PLC SHS USD G50871105 1,455 9,949 SH   DFND 1 9,949 0 0
LIBERTY MEDIA CORP DELAWARE COM C BRAVES GRP 531229888 3,925 155,340 SH   SOLE   155,340 0 0
LIBERTY MEDIA CORP DELAWARE COM C BRAVES GRP 531229888 8,583 339,660 SH   DFND 1 339,660 0 0
LIBERTY MEDIA CORP DELAWARE COM SER C FRMLA 531229854 1,307 34,309 SH   DFND 1 34,309 0 0
LIBERTY MEDIA CORP DELAWARE COM SER C FRMLA 531229854 598 15,691 SH   SOLE   15,691 0 0
LOXO ONCOLOGY INC COM 548862101 2,844 30,877 SH   DFND 1 30,877 0 0
LOXO ONCOLOGY INC COM 548862101 1,301 14,123 SH   SOLE   14,123 0 0
MARINUS PHARMACEUTICALS INC COM 56854Q101 520 88,516 SH   DFND 1 88,516 0 0
MARINUS PHARMACEUTICALS INC COM 56854Q101 238 40,484 SH   SOLE   40,484 0 0
MARTIN MARIETTA MATLS INC COM 573284106 874 4,237 SH   SOLE   4,237 0 0
MARTIN MARIETTA MATLS INC COM 573284106 1,910 9,263 SH   DFND 1 9,263 0 0
MAZOR ROBOTICS LTD SPONSORED ADS 57886P103 1,348 27,304 SH   SOLE   27,304 0 0
MAZOR ROBOTICS LTD SPONSORED ADS 57886P103 2,947 59,696 SH   DFND 1 59,696 0 0
MCDONALDS CORP COM 580135101 2,150 13,723 SH   DFND 1 13,723 0 0
MCDONALDS CORP COM 580135101 983 6,277 SH   SOLE   6,277 0 0
MEDICINES CO COM 584688105 1,278 34,500 SH Put SOLE   34,500 0 0
MEDICINES CO COM 584688105 1,982 53,520 SH   DFND 1 53,520 0 0
MEDICINES CO COM 584688105 907 24,480 SH   SOLE   24,480 0 0
MEDICINES CO COM 584688105 507 13,700 SH Call DFND 1 13,700 0 0
MEDICINES CO COM 584688105 233 6,300 SH Call SOLE   6,300 0 0
MEDICINES CO COM 584688105 2,797 75,500 SH Put DFND 1 75,500 0 0
MICROSOFT CORP COM 594918104 1,789 24,015 SH   DFND 1 24,015 0 0
MICROSOFT CORP COM 594918104 818 10,985 SH   SOLE   10,985 0 0
MYOKARDIA INC COM 62857M105 1,646 38,424 SH   DFND 1 38,424 0 0
MYOKARDIA INC COM 62857M105 753 17,576 SH   SOLE   17,576 0 0
NETFLIX INC COM 64110L106 5,972 32,932 SH   DFND 1 32,932 0 0
NETFLIX INC COM 64110L106 2,733 15,068 SH   SOLE   15,068 0 0
PORTOLA PHARMACEUTICALS INC COM 737010108 2,150 39,792 SH   DFND 1 39,792 0 0
PORTOLA PHARMACEUTICALS INC COM 737010108 984 18,208 SH   SOLE   18,208 0 0
POWERSHARES QQQ TRUST UNIT SER 1 73935A104 18,254 125,500 SH Put SOLE   125,500 0 0
POWERSHARES QQQ TRUST UNIT SER 1 73935A104 39,926 274,500 SH Put DFND 1 274,500 0 0
RED HAT INC COM 756577102 870 7,847 SH   SOLE   7,847 0 0
RED HAT INC COM 756577102 1,902 17,153 SH   DFND 1 17,153 0 0
REEDS INC COM 758338107 43 19,325 SH   DFND 1 19,325 0 0
REEDS INC COM 758338107 19 8,839 SH   SOLE   8,839 0 0
REGENXBIO INC COM 75901B107 678 20,585 SH   DFND 1 20,585 0 0
REGENXBIO INC COM 75901B107 310 9,415 SH   SOLE   9,415 0 0
RINGCENTRAL INC CL A 76680R206 4,125 98,810 SH   DFND 1 98,810 0 0
RINGCENTRAL INC CL A 76680R206 1,887 45,190 SH   SOLE   45,190 0 0
ROKU INC COM CL A 77543R102 600 22,603 SH   SOLE   22,603 0 0
ROKU INC COM CL A 77543R102 1,311 49,397 SH   DFND 1 49,397 0 0
SAGE THERAPEUTICS INC COM 78667J108 642 10,300 SH Call DFND 1 10,300 0 0
SAGE THERAPEUTICS INC COM 78667J108 293 4,700 SH Call SOLE   4,700 0 0
SAREPTA THERAPEUTICS INC COM 803607100 3,112 68,608 SH   DFND 1 68,608 0 0
SAREPTA THERAPEUTICS INC COM 803607100 1,424 31,392 SH   SOLE   31,392 0 0
SIENTRA INC COM 82621J105 2,324 150,909 SH   DFND 1 150,909 0 0
SIENTRA INC COM 82621J105 1,064 69,091 SH   SOLE   69,091 0 0
SPARK THERAPEUTICS INC COM 84652J103 1,407 15,781 SH   DFND 1 15,781 0 0
SPARK THERAPEUTICS INC COM 84652J103 644 7,219 SH   SOLE   7,219 0 0
SPDR SERIES TRUST S&P BIOTECH 78464A870 6,658 76,900 SH Put SOLE   76,900 0 0
SPDR SERIES TRUST S&P BIOTECH 78464A870 14,552 168,100 SH Put DFND 1 168,100 0 0
SUMMIT MATLS INC CL A 86614U100 749 23,380 SH   SOLE   23,380 0 0
SUMMIT MATLS INC CL A 86614U100 1,637 51,120 SH   DFND 1 51,120 0 0
TAKE-TWO INTERACTIVE SOFTWAR COM 874054109 3,976 38,897 SH   DFND 1 38,897 0 0
TAKE-TWO INTERACTIVE SOFTWAR COM 874054109 1,819 17,798 SH   SOLE   17,798 0 0
TALEND S A ADS 874224207 2,810 68,633 SH   DFND 1 68,633 0 0
TALEND S A ADS 874224207 1,284 31,367 SH   SOLE   31,367 0 0
TEMPUR SEALY INTL INC COM 88023U101 303 4,700 SH Call SOLE   4,700 0 0
TEMPUR SEALY INTL INC COM 88023U101 3,320 51,462 SH   DFND 1 51,462 0 0
TEMPUR SEALY INTL INC COM 88023U101 1,519 23,538 SH   SOLE   23,538 0 0
TEMPUR SEALY INTL INC COM 88023U101 665 10,300 SH Call DFND 1 10,300 0 0
TRIPADVISOR INC COM 896945201 539 13,300 SH Call DFND 1 13,300 0 0
TRIPADVISOR INC COM 896945201 272 6,700 SH Call SOLE   6,700 0 0
U S SILICA HLDGS INC COM 90346E103 746 24,015 SH   DFND 1 24,015 0 0
U S SILICA HLDGS INC COM 90346E103 341 10,985 SH   SOLE   10,985 0 0
UNITEDHEALTH GROUP INC COM 91324P102 2,419 12,351 SH   DFND 1 12,351 0 0
UNITEDHEALTH GROUP INC COM 91324P102 1,106 5,649 SH   SOLE   5,649 0 0
VAIL RESORTS INC COM 91879Q109 2,192 9,607 SH   DFND 1 9,607 0 0
VAIL RESORTS INC COM 91879Q109 1,002 4,393 SH   SOLE   4,393 0 0
ZOGENIX INC COM NEW 98978L204 440 12,557 SH   SOLE   12,557 0 0
ZOGENIX INC COM NEW 98978L204 962 27,443 SH   DFND 1 27,443 0 0