X0508 4 2023-09-27 0 0001598646 Minerva Neurosciences, Inc. NERV 0001226286 HASLER HANS PETER C/O MINERVA NEUROSCIENCES, INC. 1500 DISTRICT AVENUE BURLINGTON MA 01803 1 0 0 0 0 Stock Option (right to buy) 7.30 2023-09-27 4 A 0 12500 0.00 A 2033-09-26 Common Stock 12500 12500 D This option is granted to non-employee directors in accordance with the Company's compensation program for non-employee directors, which provides that each non-employee director is eligible to receive an annual option grant to purchase 12,500 shares of common stock per year. The shares subject to this option vest in four equal quarterly installments at a rate of 1/4 of the total number of shares every three months, with the first 1/4 vesting on the date that is three months following September 27, 2023 and an additional 1/4 every three months thereafter, subject in each case to the continued service of the Reporting Person as a non-employee director as of such vesting date. /s/ Marc Recht, Attorney-in-Fact 2023-09-29