X0206 3 2023-06-27 0 0001598646 Minerva Neurosciences, Inc. NERV 0000938017 BOEHRINGER INGELHEIM INTERNATIONAL GMBH BINGER STRASSE 173 55216 INGELHEIM AM RHEIN 2M GERMANY 0 0 1 0 0001984047 Boehringer AG BINGER STRASSE 173 55216 INGELHEIM AM RHEIN 2M GERMANY 0 0 1 0 Common Stock 1275000 D Pre-Funded Warrant (right to buy) 0.01 2023-06-27 Common Stock 225225 D The securities are held directly by Boehringer Ingelheim International GmbH ("International GmbH"), a wholly owned indirect subsidiary of C. H. Boehringer Sohn AG & Co. KG ("Parent"). Boehringer AG (the "GP") is the General Partner of Parent. Under Securities and Exchange Commission rules and regulations, the GP may be deemed to have indirect beneficial ownership of the shares held by International GmbH. The Pre-Funded Warrant will not expire until exercised in full. /s/ Christoph Gauger, Registered Manager (Prokurist), the GP, /s/ Martin Bergmann, Registered Manager (Prokurist), the GP 2023-07-07 /s/ Frank Huebler, Registered Manager (Prokurist), International GmbH, /s/ Dr. Martin Schwarz, Registered Manager (Prokurist), International GmbH 2023-07-07