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Net Loss Per Share - Summary of Basic and Diluted Net Loss Per Share (Detail) - USD ($)
$ / shares in Units, $ in Thousands
3 Months Ended 12 Months Ended
Dec. 31, 2016
Sep. 30, 2016
Jun. 30, 2016
Mar. 31, 2016
Dec. 31, 2015
Sep. 30, 2015
Jun. 30, 2015
Mar. 31, 2015
Dec. 31, 2016
Dec. 31, 2015
Dec. 31, 2014
Numerator:                      
Net loss attributable to common stockholders                 $ (158,987) $ (94,495) $ (36,105)
Denominator:                      
Weighted average common stock outstanding—basic                 33,492,795 27,778,288 21,574,347
Dilutive effect of shares of common stock equivalents resulting from common stock options and preferred common stock (as converted)                 0 0 0
Weighted average common stock outstanding—diluted                 33,492,795 27,778,288 21,574,347
Net loss per share attributable to common stockholders—basic and diluted $ (1.50) $ (1.15) $ (1.08) $ (0.97) $ (0.99) $ (0.84) $ (0.90) $ (0.66) $ (4.75) $ (3.40) $ (1.67)