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Stock-Based Compensation - Summary of Activity Relating to Stock Options (Detail) - USD ($)
$ / shares in Units, $ in Thousands
12 Months Ended
Dec. 31, 2016
Dec. 31, 2015
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]    
Ending balance, Outstanding Shares-Stock options 4,891,922  
Stock Options [Member]    
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]    
Beginning balance, Outstanding Shares-Stock options 3,002,809  
Granted, Stock options 1,454,568  
Exercised, Stock options (124,903)  
Forfeited, Stock options (100,667)  
Ending balance, Outstanding Shares-Stock options 4,231,807 3,002,809
Vested and expected to vest as of December 31, 2016-Stock options 3,727,837  
Vested and exercisable as of December 31, 2016-Stock options 1,702,819  
Beginning balance, Outstanding Weighted Average Exercise Price-Stock options $ 26.67  
Granted, Weighted Average Exercise Price-Stock options 35.98  
Exercised, Weighted Average Exercise Price-Stock options 8.09  
Forfeited, Weighted Average Exercise Price-Stock options 44.76  
Ending balance, Outstanding Weighted Average Exercise Price-Stock options 29.99 $ 26.67
Vested and expected to vest, Weighted Average Exercise Price-Stock options 29.36  
Vested and exercisable, Weighted Average Exercise Price-Stock options $ 24.11  
Outstanding, Weighted Average Remaining Life-Stock options 8 years 2 months 27 days 8 years 8 months 1 day
Vested and expected to vest as of December 31, 2016-Stock options 8 years 2 months 16 days  
Vested and exercisable as of December 31, 2016-Stock options 7 years 7 months 2 days  
Outstanding, Aggregate Intrinsic Value-Stock options $ 92,843 $ 96,479
Vested and expected to vest as of December 31, 2016-Stock options 84,395  
Vested and exercisable as of December 31, 2016-Stock options $ 48,096