X0306 4 2023-02-13 false 0001597553 Sage Therapeutics, Inc. SAGE 0001291963 Greene Barry E C/O SAGE THERAPEUTICS, INC. 215 FIRST STREET CAMBRIDGE MA 02142 true true false false President and CEO Stock Option (Right to Buy) 45.28 2023-02-13 4 A false 66500.00 0.00 A 2033-02-13 Common Stock 66500.00 66500.00 D The securities awarded on February 13, 2023 were in the form of stock options issued pursuant to the Sage Therapeutics, Inc. 2014 Stock Option and Incentive Plan. Options to purchase 16,625 shares of common stock shall vest on the one year anniversary of February 13, 2023, with 49,875 shares vesting in 36 equal monthly installments thereafter. /s/ Jennifer Fitzpatrick, as Attorney-in-Fact for Barry Greene 2023-02-15