X0306 4 2019-05-10 false 0001597553 Sage Therapeutics, Inc. SAGE 0001320559 Cook Anne Marie C/O SAGE THERAPEUTICS, INC. 215 FIRST STREET CAMBRIDGE MA 02142 false true false false SVP, GC & Secretary Common Stock 2019-05-10 4 M false 15000.00 28.63 A 15000.00 D Common Stock 2019-05-10 4 S false 15000.00 166.14 D 0.00 D Common Stock 2019-05-10 4 M false 700.00 56.27 A 700.00 D Stock Option (Right to Buy) 28.63 2019-05-10 4 M false 15000.00 0.00 D 2026-02-08 Common Stock 15000.00 15000.00 D Stock Option (Right to Buy) 56.27 2019-05-10 4 M false 700.00 0.00 D 2025-09-16 Common Stock 700.00 109300.00 D The exercises reported on this Form 4 were effected pursuant to a trading plan adopted pursuant to Rule 10b5-1 under the Securities Exchange Act of 1934, as amended. The securities awarded on February 8, 2016 were in the form of stock options issued pursuant to the Sage Therapeutics, Inc. 2014 Stock Option and Incentive Plan. Options to purchase 5,000 shares of common stock vested on February 8, 2017, with 15,000 shares vesting in 36 equal monthly installments thereafter. Options to purchase 10,000 shares of common stock shall vest periodically upon the Company reaching certain milestone. Reflects the balance after 10,000 options were forfeited due to unmet performance condition. The stock option award was issued pursuant to the Sage Therapeutics, Inc. 2014 Stock Option and Incentive Plan. 27,500 shares vested on September 16, 2016 with the remaining shares vesting in equal monthly installments over the 36 months following September 16, 2016. /s/ Anne Marie Cook 2019-05-10