X0306 4 2018-06-06 false 0001597553 Sage Therapeutics, Inc. SAGE 0001235598 FRATES JAMES M C/O SAGE THERAPEUTICS, INC. 215 FIRST STREET CAMBRIDGE MA 02142 true false false false Stock Option (Right to Buy) 154.06 2018-06-06 4 A false 10000.00 0.00 A 2028-06-06 Common Stock 10000.00 10000.00 D The stock option award was issued pursuant to the Sage Therapeutics, Inc., 2014 Stock Option and Incentive Plan. The option will vest in full upon the earlier to occur of June 6, 2019 or the day immediately prior to the 2019 Annual Meeting of Sage's stockholders, subject to continued service as a director on such date. /s/ Anne Marie Cook, as Attorney-in-Fact for James M. Frates 2018-06-08