X0306 4 2016-01-25 false 0001597553 Sage Therapeutics, Inc. SAGE 0001612861 Robichaud Albert C/O SAGE THERAPEUTICS, INC. 215 FIRST STREET CAMBRIDGE MA 02142 false true false false Chief Scientific Officer Common Stock 2016-01-25 4 S false 20000.00 40.02 D 162222.00 D The sales reported on this Form 4 were effected pursuant to a trading plan adopted pursuant to Rule 10b5-1 under the Securities Exchange Act of 1934, as amended. This transaction was executed in multiple trades at prices ranging from $40.00 USD to $40.13 USD. The price reported above reflects the weighted average sale price. /s/ Kimi Iguchi, as Attorney-in-Fact for Albert Robichaud 2016-01-26