X0206 3 2015-09-16 0 0001597553 Sage Therapeutics, Inc. SAGE 0001320559 Cook Anne Marie C/O SAGE THERAPEUTICS, INC. 215 FIRST STREET CAMBRIDGE MA 02142 false true false false General Counsel Common Stock 0.00 D No securities are beneficially owned. /s/ Erin Lanciani, Attorney-in-Fact for Anne Marie Cook 2015-09-17