X0306 4 2015-06-15 false 0001597553 Sage Therapeutics, Inc. SAGE 0001042021 JONAS JEFFREY M C/O SAGE THERAPEUTICS, INC. 215 FIRST STREET CAMBRIDGE MA 02142 true true false false See Remarks Common Stock 2015-06-15 4 M false 83374.00 0.45 A 89374.00 D Common Stock 2015-06-15 4 S false 1554.00 83.8877 D 87820.00 D Common Stock 2015-06-15 4 S false 2420.00 81.5066 D 85400.00 D Common Stock 2015-06-15 4 S false 5707.00 79.9696 D 79693.00 D Common Stock 2015-06-15 4 S false 62364.00 78.8775 D 17329.00 D Common Stock 2015-06-15 4 S false 11329.00 78.2216 D 6000.00 D Common Stock 2015-06-16 4 M false 115226.00 0.45 A 121226.00 D Common Stock 2015-06-16 4 S false 6804.00 78.1261 D 114422.00 D Common Stock 2015-06-16 4 S false 14146.00 76.8483 D 100276.00 D Common Stock 2015-06-16 4 S false 64973.00 76.0886 D 35303.00 D Common Stock 2015-06-16 4 S false 29303.00 75.5133 D 6000.00 D Common Stock 2015-06-15 4 M false 32745.00 0.45 A 38745.00 D Common Stock 2015-06-16 4 M false 45255.00 0.45 A 84000.00 D Stock Option (Right to Buy) 0.45 2015-06-15 4 M false 128629.00 0.00 D 2023-08-12 Common Stock 128629.00 0.00 D Stock Option (Right to Buy) 0.45 2015-06-16 4 M false 147971.00 0.00 D 2023-08-12 Common Stock 147971.00 0.00 D The sales reported on this Form 4 were effected pursuant to a trading plan adopted pursuant to Rule 10b5-1 under the Securities Exchange Act of 1934, as amended. This transaction was executed in multiple trades at prices ranging from $75.50 USD to $75.55 USD. The price reported above reflects the weighted average sale price. The stock option award was issued pursuant to the Sage Therapeutics, Inc., 2011 Stock Option and Incentive Plan. The option shall vest in full on August 12, 2017, subject to continued service through such date. This transaction was executed in multiple trades at prices ranging from $83.79 USD to $84.01 USD. The price reported above reflects the weighted average sale price. This transaction was executed in multiple trades at prices ranging from $80.64 USD to $81.63 USD. The price reported above reflects the weighted average sale price. This transaction was executed in multiple trades at prices ranging from $79.625 USD to $80.61 USD. The price reported above reflects the weighted average sale price. This transaction was executed in multiple trades at prices ranging from $78.58 USD to $79.58 USD. The price reported above reflects the weighted average sale price. This transaction was executed in multiple trades at prices ranging from $77.86 USD to $78.44 USD. The price reported above reflects the weighted average sale price. This transaction was executed in multiple trades at prices ranging from $77.60 USD to $78.595 USD. The price reported above reflects the weighted average sale price. This transaction was executed in multiple trades at prices ranging from $76.56 USD to $77.56 USD. The price reported above reflects the weighted average sale price. This transaction was executed in multiple trades at prices ranging from $75.555 USD to $76.555 USD. The price reported above reflects the weighted average sale price. /s/ Laurie Burlingame, as Attorney-in-Fact for Jeffrey M. Jonas 2015-06-17