Consolidated Statements of Changes in Stockholders' Equity - USD ($) $ in Thousands	Total	Common Stock [Member]	Treasury Stock [Member]	Additional Paid-in Capital [Member]	Accumulated Other Comprehensive Income (Loss) [Member]	Accumulated Deficit [Member]
Balances at Dec. 31, 2021	$ 1,729,031	$ 6	$ (400)	$ 3,227,471	$ (2,660)	$ (1,495,386)
Balances, Shares at Dec. 31, 2021		58,937,050	3,033
Issuance of common stock from exercises of stock options, Amount	1,037			1,037
Issuance of common stock from exercises of stock options, Shares		150,045
Issuance of common stock under the employee stock purchase plan	2,346			2,346
Issuance of common stock under the employee stock purchase plan, Shares		57,239
Vesting of restricted stock units, net of employee tax obligations	(43)			(43)
Vesting of restricted stock units, net of employee tax obligations, Shares		364,791
Stock-based compensation expense	60,558			60,558
Change in unrealized gain (loss) on available-for-sale securities	(7,546)				(7,546)
Net Income (Loss)	(532,784)					(532,784)
Balances at Dec. 31, 2022	1,252,599	$ 6	$ (400)	3,291,369	(10,206)	(2,028,170)
Balances, Shares at Dec. 31, 2022		59,509,125	3,033
Issuance of common stock from exercises of stock options, Amount	1,293			1,293
Issuance of common stock from exercises of stock options, Shares		72,090
Issuance of common stock under the employee stock purchase plan	6,519			6,519
Issuance of common stock under the employee stock purchase plan, Shares		164,043
Vesting of restricted stock units, net of employee tax obligations	(903)			(903)
Vesting of restricted stock units, net of employee tax obligations, Shares		298,385
Stock-based compensation expense	72,119			72,119
Change in unrealized gain (loss) on available-for-sale securities	9,392				9,392
Net Income (Loss)	(541,489)					(541,489)
Balances at Dec. 31, 2023	799,530	$ 6	$ (400)	3,370,397	(814)	(2,569,659)
Balances, Shares at Dec. 31, 2023		60,043,643	3,033
Issuance of common stock from exercises of stock options, Amount	78			78
Issuance of common stock from exercises of stock options, Shares		10,062
Issuance of common stock under the employee stock purchase plan	2,941			2,941
Issuance of common stock under the employee stock purchase plan, Shares		216,886
Vesting of restricted stock units, net of employee tax obligations	(403)			(403)
Vesting of restricted stock units, net of employee tax obligations, Shares		385,618
Stock-based compensation expense	54,504			54,504
Issuance of common stock upon public offering, net of issuance costs	8,047			8,047
Issuance of common stock upon public offering, net of issuance costs, Shares		700,000
Change in unrealized gain (loss) on available-for-sale securities	1,058				1,058
Net Income (Loss)	(400,666)					(400,666)
Balances at Dec. 31, 2024	$ 465,089	$ 6	$ (400)	$ 3,435,564	$ 244	$ (2,970,325)
Balances, Shares at Dec. 31, 2024		61,356,209	3,033