Condensed Consolidated Statements of Changes in Stockholders' Equity (Unaudited) - USD ($) $ in Thousands	Total	Common Stock [Member]	Treasury Stock [Member]	Additional Paid-in Capital [Member]	Accumulated Other Comprehensive Income (Loss) [Member]	Accumulated Deficit [Member]
Balances at Dec. 31, 2022	$ 1,252,599	$ 6	$ (400)	$ 3,291,369	$ (10,206)	$ (2,028,170)
Balances, Shares at Dec. 31, 2022		59,509,125	3,033
Issuance of common stock from exercises of stock options, Amount	438			438
Issuance of common stock from exercises of stock options, Shares		52,058
Issuance of common stock under the employee stock purchase plan	2,863			2,863
Issuance of common stock under the employee stock purchase plan, Shares		76,105
Stock-based compensation expense	19,568			19,568
Change in unrealized gain (loss) on available-for-sale securities	5,118				5,118
Vesting of restricted stock units, net of employee tax obligations	(629)			(629)
Vesting of restricted stock units, net of employee tax obligations, Shares		124,713
Net loss	(146,828)					(146,828)
Balances at Mar. 31, 2023	1,133,129	$ 6	$ (400)	3,313,609	(5,088)	(2,174,998)
Balance, Shares at Mar. 31, 2023		59,762,001	3,033
Balances at Dec. 31, 2022	1,252,599	$ 6	$ (400)	3,291,369	(10,206)	(2,028,170)
Balances, Shares at Dec. 31, 2022		59,509,125	3,033
Net loss	(508,783)
Balances at Sep. 30, 2023	816,659	$ 6	$ (400)	3,357,741	(3,735)	(2,536,953)
Balance, Shares at Sep. 30, 2023		59,967,516	3,033
Balances at Mar. 31, 2023	1,133,129	$ 6	$ (400)	3,313,609	(5,088)	(2,174,998)
Balances, Shares at Mar. 31, 2023		59,762,001	3,033
Issuance of common stock from exercises of stock options, Amount	855			855
Issuance of common stock from exercises of stock options, Shares		20,032
Stock-based compensation expense	11,281			11,281
Change in unrealized gain (loss) on available-for-sale securities	(556)				(556)
Vesting of restricted stock units, net of employee tax obligations	(8)			(8)
Vesting of restricted stock units, net of employee tax obligations, Shares		13,972
Net loss	(160,325)					(160,325)
Balances at Jun. 30, 2023	984,376	$ 6	$ (400)	3,325,737	(5,644)	(2,335,323)
Balance, Shares at Jun. 30, 2023		59,796,005	3,033
Issuance of common stock under the employee stock purchase plan	3,656			3,656
Issuance of common stock under the employee stock purchase plan, Shares		87,938
Stock-based compensation expense	28,352			28,352
Change in unrealized gain (loss) on available-for-sale securities	1,909				1,909
Vesting of restricted stock units, net of employee tax obligations	(4)			(4)
Vesting of restricted stock units, net of employee tax obligations, Shares		83,573
Net loss	(201,630)					(201,630)
Balances at Sep. 30, 2023	816,659	$ 6	$ (400)	3,357,741	(3,735)	(2,536,953)
Balance, Shares at Sep. 30, 2023		59,967,516	3,033
Balances at Dec. 31, 2023	799,530	$ 6	$ (400)	3,370,397	(814)	(2,569,659)
Balances, Shares at Dec. 31, 2023		60,043,643	3,033
Issuance of common stock from exercises of stock options, Amount	52			52
Issuance of common stock from exercises of stock options, Shares		7,142
Issuance of common stock under the employee stock purchase plan	1,507			1,507
Issuance of common stock under the employee stock purchase plan, Shares		61,402
Stock-based compensation expense	13,170			13,170
Change in unrealized gain (loss) on available-for-sale securities	27				27
Vesting of restricted stock units, net of employee tax obligations	(2)			(2)
Vesting of restricted stock units, net of employee tax obligations, Shares		69,844
Net loss	(108,483)					(108,483)
Balances at Mar. 31, 2024	705,801	$ 6	$ (400)	3,385,124	(787)	(2,678,142)
Balance, Shares at Mar. 31, 2024		60,182,031	3,033
Balances at Dec. 31, 2023	799,530	$ 6	$ (400)	3,370,397	(814)	(2,569,659)
Balances, Shares at Dec. 31, 2023		60,043,643	3,033
Net loss	(304,888)
Balances at Sep. 30, 2024	551,835	$ 6	$ (400)	3,425,875	901	(2,874,547)
Balance, Shares at Sep. 30, 2024		61,173,263	3,033
Balances at Mar. 31, 2024	705,801	$ 6	$ (400)	3,385,124	(787)	(2,678,142)
Balances, Shares at Mar. 31, 2024		60,182,031	3,033
Issuance of common stock from exercises of stock options, Amount	26			26
Issuance of common stock from exercises of stock options, Shares		2,920
Stock-based compensation expense	16,947			16,947
Issuance of common stock upon public offering, net of issuance costs	8,047			8,047
Issuance of common stock upon public offering, net of issuance costs, Shares		700,000
Change in unrealized gain (loss) on available-for-sale securities	96				96
Vesting of restricted stock units, net of employee tax obligations	(1)			(1)
Vesting of restricted stock units, net of employee tax obligations, Shares		9,983
Net loss	(102,854)					(102,854)
Balances at Jun. 30, 2024	628,062	$ 6	$ (400)	3,410,143	(691)	(2,780,996)
Balance, Shares at Jun. 30, 2024		60,894,934	3,033
Issuance of common stock under the employee stock purchase plan	2,182			2,182
Issuance of common stock under the employee stock purchase plan, Shares		155,484
Stock-based compensation expense	13,949			13,949
Change in unrealized gain (loss) on available-for-sale securities	1,592				1,592
Vesting of restricted stock units, net of employee tax obligations	(399)			(399)
Vesting of restricted stock units, net of employee tax obligations, Shares		122,845
Net loss	(93,551)					(93,551)
Balances at Sep. 30, 2024	$ 551,835	$ 6	$ (400)	$ 3,425,875	$ 901	$ (2,874,547)
Balance, Shares at Sep. 30, 2024		61,173,263	3,033