Condensed Consolidated Statements of Operations and Comprehensive Loss - USD ($) $ in Thousands	3 Months Ended		9 Months Ended
	Sep. 30, 2024	Sep. 30, 2023	Sep. 30, 2024	Sep. 30, 2023
Total revenue	$ 11,871	$ 2,716	$ 28,427	$ 8,483
Operating costs and expenses:
Cost of revenues	5,278	905	7,955	1,339
Research and development	54,576	101,919	188,873	291,905
Selling, general and administrative	53,219	78,142	161,775	219,415
Restructuring		33,599	597	33,599
Total operating costs and expenses	113,073	214,565	358,603	546,258
Loss from operations	(101,202)	(211,849)	(330,176)	(537,775)
Interest income, net	7,642	10,274	25,277	29,276
Other income (expense), net	9	(55)	11	(284)
Net loss	$ (93,551)	$ (201,630)	$ (304,888)	$ (508,783)
Net loss per share - basic	$ (1.53)	$ (3.37)	$ (5.03)	$ (8.51)
Net loss per share - diluted	$ (1.53)	$ (3.37)	$ (5.03)	$ (8.51)
Weighted average number of common shares outstanding— basic	61,116,524	59,912,378	60,598,909	59,786,254
Weighted average number of common shares outstanding— diluted	61,116,524	59,912,378	60,598,909	59,786,254
Comprehensive loss:
Net loss	$ (93,551)	$ (201,630)	$ (304,888)	$ (508,783)
Other comprehensive items:
Unrealized gain on marketable securities	1,592	1,909	1,715	6,471
Total comprehensive loss	(91,959)	(199,721)	(303,173)	(502,312)
Product Revenue [Member]
Total revenue	843	$ 2,716	3,132	8,469
Collaboration Revenue - Related Party [Member]
Total revenue	$ 11,028		24,661
Other Collaboration Revenue [Member]
Total revenue			$ 634	$ 14