Condensed Consolidated Statements of Operations and Comprehensive Loss - USD ($) $ in Thousands	3 Months Ended		6 Months Ended
	Jun. 30, 2024	Jun. 30, 2023	Jun. 30, 2024	Jun. 30, 2023
Total revenue	$ 8,654	$ 2,474	$ 16,556	$ 5,768
Operating costs and expenses:
Cost of revenues	1,407	205	2,676	435
Research and development	62,564	97,161	134,297	189,987
Selling, general and administrative	55,983	75,565	108,556	141,273
Total operating costs and expenses	119,954	172,931	245,529	331,695
Loss from operations	(111,300)	(170,457)	(228,973)	(325,927)
Interest income, net	8,431	10,173	17,634	19,003
Other income (expense), net	15	(41)	2	(229)
Net loss	$ (102,854)	$ (160,325)	$ (211,337)	$ (307,153)
Net loss per share - basic	$ (1.7)	$ (2.68)	$ (3.5)	$ (5.14)
Net loss per share - diluted	$ (1.7)	$ (2.68)	$ (3.5)	$ (5.14)
Weighted average number of common shares outstanding— basic	60,538,319	59,769,640	60,337,258	59,722,147
Weighted average number of common shares outstanding— diluted	60,538,319	59,769,640	60,337,258	59,722,147
Comprehensive loss:
Net loss	$ (102,854)	$ (160,325)	$ (211,337)	$ (307,153)
Other comprehensive items:
Unrealized gain (loss) on marketable securities	96	(556)	123	4,562
Total comprehensive loss	(102,758)	(160,881)	(211,214)	(302,591)
Product Revenue [Member]
Total revenue	600	2,460	2,289	5,754
Collaboration Revenue - Related Party [Member]
Total revenue	7,420		13,633
Other Collaboration Revenue [Member]
Total revenue	$ 634	$ 14	$ 634	$ 14