Condensed Consolidated Balance Sheets - USD ($) $ in Thousands	Jun. 30, 2023	Dec. 31, 2022
Current assets:
Cash and cash equivalents	$ 121,416	$ 162,700
Marketable securities	881,200	1,109,794
Prepaid expenses and other current assets	46,321	50,826
Total current assets	1,064,027	1,336,980
Property and equipment, net	2,480	2,898
Restricted cash	1,332	1,269
Right-of-use operating asset	7,560	10,532
Other long-term assets	6,889	4,770
Total assets	1,082,288	1,356,449
Current liabilities:
Accounts payable	9,283	18,950
Accrued expenses	79,799	72,666
Operating lease liability, current portion	7,725	7,643
Total current liabilities	96,807	99,259
Operating lease liability, net of current portion	1,003	4,491
Other liabilities	102	100
Total liabilities	97,912	103,850
Commitments and contingencies (Note 5)
Stockholders’ equity:
Preferred stock, $0.0001 par value per share; 5,000,000 shares authorized at June 30, 2023 and December 31, 2022; no shares issued or outstanding at June 30, 2023 and December 31, 2022
Common stock, $0.0001 par value per share; 120,000,000 shares authorized at June 30, 2023 and December 31, 2022; 59,799,038 and 59,512,158 shares issued at June 30, 2023 and December 31, 2022; 59,796,005 and 59,509,125 shares outstanding at June 30, 2023 and December 31, 2022	6	6
Treasury stock, at cost, 3,033 shares at June 30, 2023 and December 31, 2022	(400)	(400)
Additional paid-in capital	3,325,737	3,291,369
Accumulated deficit	(2,335,323)	(2,028,170)
Accumulated other comprehensive loss	(5,644)	(10,206)
Total stockholders’ equity	984,376	1,252,599
Total liabilities and stockholders’ equity	1,082,288	1,356,449
Related Party [Member]
Current assets:
Collaboration receivable - related party	$ 15,090	$ 13,660