Condensed Consolidated Statements of Operations and Comprehensive Loss - USD ($) $ in Thousands	3 Months Ended
	Mar. 31, 2023	Mar. 31, 2022
Operating costs and expenses:
Cost of goods sold	$ 230	$ 286
Research and development	92,826	78,018
Selling, general and administrative	65,708	46,477
Total operating costs and expenses	158,764	124,781
Loss from operations	(155,470)	(123,199)
Interest income, net	8,830	1,168
Other expense, net	(188)	(24)
Net loss	$ (146,828)	$ (122,055)
Net loss per share—basic	$ (2.46)	$ (2.07)
Net loss per share—diluted	$ (2.46)	$ (2.07)
Weighted average number of common shares outstanding— basic	59,674,127	59,028,858
Weighted average number of common shares outstanding— diluted	59,674,127	59,028,858
Comprehensive loss:
Net loss	$ (146,828)	$ (122,055)
Other comprehensive items:
Unrealized gain (loss) on marketable securities	5,118	(8,541)
Total other comprehensive gain (loss)	5,118	(8,541)
Total comprehensive loss	(141,710)	(130,596)
Product Revenue [Member]
Total revenue	$ 3,294	$ 1,582