Consolidated Statements of Changes in Stockholders' Equity - USD ($) $ in Thousands	Total	Common Stock [Member]	Treasury Stock [Member]	Additional Paid-in Capital [Member]	Accumulated Other Comprehensive Gain (Loss) [Member]	Accumulated Deficit [Member]
Balances at Dec. 31, 2019	$ 944,655	$ 5	$ (400)	$ 2,587,322	$ 1,295	$ (1,643,567)
Balances, Shares at Dec. 31, 2019		51,877,194	3,033
Issuance of common stock from exercise of stock options, Amount	5,082			5,082
Issuance of common stock from exercise of stock options, Shares		117,025
Issuance of common stock under the employee stock purchase plan	4,936			4,936
Issuance of common stock under the employee stock purchase plan, Shares		72,719
Issuance of common stock under the Stock Purchase Agreement - related party	417,500	$ 1		417,499
Issuance of common stock under the Stock Purchase Agreement - related party, Shares		6,241,473
Stock-based compensation expense	94,968			94,968
Change in unrealized loss on available-for-sale securities	(880)				(880)
Net income (loss)	606,073					606,073
Balances at Dec. 31, 2020	2,072,334	$ 6	$ (400)	3,109,807	415	(1,037,494)
Balances, Shares at Dec. 31, 2020		58,308,411	3,033
Issuance of common stock from exercise of stock options, Amount	12,397			12,397
Issuance of common stock from exercise of stock options, Shares		307,378
Issuance of common stock under the employee stock purchase plan	2,761			2,761
Issuance of common stock under the employee stock purchase plan, Shares		46,759
Stock-based compensation expense	103,891			103,891
Vesting of restricted stock units, net of employee tax obligations	(1,385)			(1,385)
Vesting of restricted stock units, net of employee tax obligations, Shares		274,502
Change in unrealized loss on available-for-sale securities	(3,075)				(3,075)
Net income (loss)	(457,892)					(457,892)
Balances at Dec. 31, 2021	1,729,031	$ 6	$ (400)	3,227,471	(2,660)	(1,495,386)
Balances, Shares at Dec. 31, 2021		58,937,050	3,033
Issuance of common stock from exercise of stock options, Amount	1,037			1,037
Issuance of common stock from exercise of stock options, Shares		150,045
Issuance of common stock under the employee stock purchase plan	2,346			2,346
Issuance of common stock under the employee stock purchase plan, Shares		57,239
Stock-based compensation expense	60,558			60,558
Vesting of restricted stock units, net of employee tax obligations	(43)			(43)
Vesting of restricted stock units, net of employee tax obligations, Shares		364,791
Change in unrealized loss on available-for-sale securities	(7,546)				(7,546)
Net income (loss)	(532,784)					(532,784)
Balances at Dec. 31, 2022	$ 1,252,599	$ 6	$ (400)	$ 3,291,369	$ (10,206)	$ (2,028,170)
Balances, Shares at Dec. 31, 2022		59,509,125	3,033