Net Loss Per Share - Summary of Basic and Diluted Net Loss Per Share (Detail) - USD ($) $ / shares in Units, $ in Thousands	3 Months Ended						9 Months Ended
	Sep. 30, 2022	Jun. 30, 2022	Mar. 31, 2022	Sep. 30, 2021	Jun. 30, 2021	Mar. 31, 2021	Sep. 30, 2022	Sep. 30, 2021
Numerator:
Net loss	$ (137,323)	$ (126,260)	$ (122,055)	$ (130,171)	$ (107,245)	$ (95,764)	$ (385,638)	$ (333,180)
Denominator:
Weighted average number of common shares outstanding— basic	59,428,123			58,819,548			59,242,563	58,593,743
Dilutive effect of shares of common stock equivalents resulting from common stock options and restricted stock units	0			0			0	0
Weighted average common stock outstanding —diluted	59,428,123			58,819,548			59,242,563	58,593,743
Net loss per share—basic	$ (2.31)			$ (2.21)			$ (6.51)	$ (5.69)
Net loss per share—diluted	$ (2.31)			$ (2.21)			$ (6.51)	$ (5.69)