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Stock-Based Compensation - Summary of Activity Relating to Time Based and Performance Based Stock Options (Detail)
$ / shares in Units, $ in Thousands
9 Months Ended 12 Months Ended
Sep. 30, 2022
USD ($)
$ / shares
shares
Dec. 31, 2021
USD ($)
$ / shares
shares
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]    
Ending balance, Outstanding Shares 9,088,581  
Stock Options [Member]    
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]    
Beginning balance, Outstanding Shares 7,283,439  
Granted, Shares 1,008,027  
Exercised, Shares (149,083)  
Forfeited, Shares (443,059)  
Ending balance, Outstanding Shares 7,699,324 7,283,439
Exercisable, Shares 4,953,687  
Beginning balance, Outstanding Weighted Average Exercise Price | $ / shares $ 84.17  
Granted, Weighted Average Exercise Price | $ / shares 39.59  
Exercised, Weighted Average Exercise Price | $ / shares 6.73  
Forfeited, Weighted Average Exercise Price | $ / shares 94.18  
Ending balance, Outstanding Weighted Average Exercise Price | $ / shares 79.26 $ 84.17
Exercisable, Weighted Average Exercise Price | $ / shares $ 85.77  
Outstanding, Weighted Average Remaining Life 6 years 6 months 10 days 6 years 8 months 26 days
Exercisable, Weighted Average Remaining Life 5 years 4 months 20 days  
Outstanding, Aggregate Intrinsic Value | $ $ 8,606 $ 16,590
Exercisable, Aggregate Intrinsic Value | $ $ 6,584