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Stock-Based Compensation - Schedule of Weighted-Average Assumptions Used in Black-Scholes Option-Pricing Model to Estimate Fair Value of Employee Stock Options/Purchases at Grant Date (Details)
12 Months Ended
Dec. 31, 2022
Dec. 31, 2021
Dec. 31, 2020
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]      
Expected term (in years) 6 years    
Expected volatility (%) 68.80%    
Risk-free interest rate (%) 0.70%    
Expected dividend yield (%) 0.00%    
Risk-free interest rate (%), Minimum     0.09%
Risk-free interest rate (%), Maximum     0.17%
2015 Employee Stock Purchase Plan      
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]      
Expected term (in years) 6 months 6 months  
Expected volatility (%)     83.00%
Expected dividend yield (%) 0.00% 0.00% 0.00%
Risk-free interest rate (%), Minimum 0.22% 0.05%  
Risk-free interest rate (%), Maximum 2.52% 0.09%  
2015 Employee Stock Purchase Plan | Minimum      
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]      
Expected term (in years)     3 months 18 days
Expected volatility (%) 83.20% 84.20%  
2015 Employee Stock Purchase Plan | Maximum      
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]      
Expected term (in years)     6 months
Expected volatility (%) 83.80% 86.00%