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Stock-Based Compensation - Schedule of Weighted-Average Assumptions Used in Black-Scholes Option-Pricing Model to Estimate Fair Value of Employee Stock Options/Purchases at Grant Date (Details)
12 Months Ended
Dec. 31, 2021
Dec. 31, 2020
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]    
Expected term (in years) 6 years 6 years
Expected volatility (%) 68.80% 60.70%
Risk-free interest rate (%) 0.70% 2.40%
Expected dividend yield (%) 0.00% 0.00%
2015 Employee Stock Purchase Plan    
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]    
Expected term (in years) 6 months  
Expected volatility (%)   83.00%
Expected dividend yield (%) 0.00% 0.00%
Risk-free interest rate (%), Minimum 0.05% 0.09%
Risk-free interest rate (%), Maximum 0.09% 0.17%
2015 Employee Stock Purchase Plan | Minimum    
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]    
Expected term (in years) 3 months  
Expected volatility (%) 84.20%  
2015 Employee Stock Purchase Plan | Maximum    
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]    
Expected term (in years) 6 months  
Expected volatility (%) 86.00%