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Equity Financing - Additional Information (Detail) - USD ($)
1 Months Ended 9 Months Ended
Dec. 06, 2019
Dec. 03, 2019
Aug. 17, 2018
Aug. 14, 2018
Feb. 28, 2018
Jan. 31, 2017
Sep. 30, 2016
Sep. 30, 2020
Jan. 31, 2019
2016 Placement Warrants                  
Subsidiary Sale Of Stock [Line Items]                  
Warrants to purchase common stock, shares             1,380,745    
Warrant exercise price             $ 2.95 $ 2.95  
Warrant expiration period             7 years 7 years  
2017 Placement Warrants                  
Subsidiary Sale Of Stock [Line Items]                  
Warrants to purchase common stock, shares           1,720,512      
Warrant exercise price           $ 3.17   $ 3.17  
Warrant expiration date           2024-01      
Warrant expiration period               7 years  
Warrant exercisable date           2017-07      
Underwriters | Common Stock                  
Subsidiary Sale Of Stock [Line Items]                  
Underwriting agreement date   Dec. 03, 2019   Aug. 14, 2018          
Number of shares issued in transaction   41,550,000   16,216,217          
Sale of stock, price   $ 3.13   $ 9.25          
Option to purchase additional shares   30 days   30 days          
Aggregate proceeds from issuance of common stock $ 138,600,000   $ 161,900,000            
Underwriters | Common Stock | Maximum                  
Subsidiary Sale Of Stock [Line Items]                  
Number of additional shares issued in transaction   6,232,500   2,432,432          
March 2018 Direct Registered Offering                  
Subsidiary Sale Of Stock [Line Items]                  
Proceed from private placement and equity issuances, gross         $ 59,100,000        
March 2018 Direct Registered Offering | Common Stock                  
Subsidiary Sale Of Stock [Line Items]                  
Stock issued during period         4,090,000        
March 2018 Direct Registered Offering | Series A Convertible Preferred Stock                  
Subsidiary Sale Of Stock [Line Items]                  
Stock issued during period         3,000,581        
March 2018 Direct Registered Offering Warrants                  
Subsidiary Sale Of Stock [Line Items]                  
Warrants to purchase common stock, shares         1,418,116        
Warrant exercise price         $ 8.31        
Warrant expiration date         2025-03        
2016 Private Placement | Common Stock                  
Subsidiary Sale Of Stock [Line Items]                  
Number of shares issued in transaction             4,602,506    
Proceed from private placement and equity issuances, gross             $ 13,800,000    
2017 Private Placement | Common Stock                  
Subsidiary Sale Of Stock [Line Items]                  
Number of shares issued in transaction           8,602,589      
Proceed from private placement and equity issuances, gross           $ 26,100,000      
At The Market Offering Program January 2019                  
Subsidiary Sale Of Stock [Line Items]                  
Aggregate proceeds from issuance of common stock               $ 0  
At The Market Offering Program January 2019 | Maximum                  
Subsidiary Sale Of Stock [Line Items]                  
Maximum aggregate offering price                 $ 250,000,000.0
Maximum common stock saleable shares, value                 $ 100,000,000.0