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Debt - Additional Information (Detail) - USD ($)
1 Months Ended 3 Months Ended 12 Months Ended
Jun. 26, 2015
Nov. 30, 2014
Aug. 31, 2014
Mar. 26, 2016
Dec. 31, 2015
Dec. 31, 2014
Mar. 31, 2016
Mar. 21, 2016
Dec. 31, 2013
Dec. 31, 2008
Debt Instrument [Line Items]                    
Debt instrument, interest rate percentage                   6.00%
Convertible preferred stock warrant liability         $ 0 $ 138,000        
Debt maturity date         Dec. 31, 2009          
Proceeds from issuance of convertible notes, net           9,941,000        
Conversion of convertible notes into new Series C convertible preferred stock           10,129,000        
Series C Convertible Preferred Stock                    
Debt Instrument [Line Items]                    
Exercise price         $ 5.08          
Hercules Term Loan                    
Debt Instrument [Line Items]                    
Amount outstanding under the agreement           $ 15,000,000        
Stated Percentage Rate Range, Maximum           10.25%        
Maturity Date Range, End         Jun. 01, 2017          
Unamortized debt discount         $ 466,000          
Beginning period for interest payments         Jan. 01, 2015          
Frequency of Periodic Payment         Monthly principal and interest payments          
Beginning period for interest payments         Jan. 31, 2014          
Exercisable from Issuance         10 years          
Exercisable after an IPO         5 years          
Convertible preferred stock warrant liability         $ 158,000          
Fair value of warrant assumption, expected term         2 years          
Fair value of warrant assumption, expected volatility         30.00%          
Fair value of warrant assumption, risk-free interest rate         0.40%          
Fair value of warrant assumption, expected dividend yield         0.00%          
Hercules Term Loan | Series C Convertible Preferred Stock                    
Debt Instrument [Line Items]                    
Vested and exercisable warrant to purchase         128,231          
Exercise price         $ 5.84          
Hercules Term Loan | First 12 months                    
Debt Instrument [Line Items]                    
Prepayment penalty         5.00%          
Hercules Term Loan | Thereafter Until Maturity                    
Debt Instrument [Line Items]                    
Prepayment penalty         1.00%          
Hercules Term Loan | Prime Rate                    
Debt Instrument [Line Items]                    
Spread on interest rate         7.00%          
CRG Term Loan                    
Debt Instrument [Line Items]                    
Frequency of Periodic Payment         Quarterly          
Maximum borrowing capacity $ 50,000,000                  
Current borrowing capacity 30,000,000                  
Remaining borrowing capacity 20,000,000                  
Debt drawn $ 30,000,000                  
Debt maturity date         Jun. 26, 2020          
Line of credit facility, covenant terms         On March 24, 2016, the Company and CRG executed an amendment to the original terms of the CRG Term Loan such that, with regard to the conditions for borrowing the remaining $20.0 million available under the CRG Term Loan, the Company may, at its election, draw down (i) an amount of either $10.0 million or $15.0 million in up to two advances upon achievement of a minimum of $15.0 million of aggregate product and service revenue during any consecutive 12 month period ending on or before March 31, 2016 and (ii) an additional $5.0 million (or $10.0 million, if the previous draw made was only in an amount of $10.0 million) upon achievement of a minimum of $25.0 million of aggregate product and service revenue during any consecutive 12 month period ending on or before December 31, 2016 and upon execution of the first sales contract of the Company’s second generation product.          
Facility fee 7.00%                  
CRG Term Loan | Subsequent Event                    
Debt Instrument [Line Items]                    
Proceeds from term loan       $ 40,000,000            
Post Money Valuation Minimum Amount             $ 120,000,000      
CRG Term Loan | Subsequent Event | Milestone One                    
Debt Instrument [Line Items]                    
Remaining borrowing capacity             10,000,000      
Debt drawn               $ 10,000,000    
Required minimum gross revenue             15,000,000      
CRG Term Loan | Subsequent Event | Milestone Two                    
Debt Instrument [Line Items]                    
Remaining borrowing capacity             5,000,000      
Debt drawn               $ 15,000,000    
Required minimum gross revenue             $ 25,000,000      
CRG Term Loan | First 12 months                    
Debt Instrument [Line Items]                    
Debt instrument, interest rate percentage 12.50%                  
Prepayment penalty 3.00%                  
Debt instrument cash interest rate percentage 8.00%                  
Deferred payment in-kind interest rate 4.50%                  
CRG Term Loan | After Year 1 but on or Before Year 2                    
Debt Instrument [Line Items]                    
Debt instrument, interest rate percentage 12.50%                  
Prepayment penalty 2.00%                  
Debt instrument cash interest rate percentage 8.00%                  
Deferred payment in-kind interest rate 4.50%                  
CRG Term Loan | After Year 2 but on or Before Year 3                    
Debt Instrument [Line Items]                    
Debt instrument, interest rate percentage 12.50%                  
Prepayment penalty 1.00%                  
CRG Term Loan | After Year 3 Thereafter Until Maturity                    
Debt Instrument [Line Items]                    
Prepayment penalty 0.00%                  
2014 Convertible Promissory Notes                    
Debt Instrument [Line Items]                    
Aggregate principal amount     $ 10,000,000              
Additional borrowing capacity     1,500,000              
Proceeds from issuance of convertible notes, net   $ 6,100,000 $ 3,900,000              
Interest rate         8.00%          
Maturity date         2015-11          
Conversion of convertible notes into new Series C convertible preferred stock         $ 10,200,000          
Longer outstanding         0          
Debt instrument available for issuance         0          
2014 Convertible Promissory Notes | Series C Convertible Preferred Stock                    
Debt Instrument [Line Items]                    
Unamortized debt discount         $ 0 $ 44,000     $ 0  
Exercise price         $ 5.84          
Stock issued convertible debt         1,739,405 1,739,405        
Deferred Payment In-Kind Interest | Hercules Term Loan                    
Debt Instrument [Line Items]                    
Debt instrument, interest rate percentage         1.50%