Condensed Consolidated Balance Sheets - USD ($) $ in Thousands	Sep. 30, 2022	Dec. 31, 2021
Current assets:
Cash and cash equivalents	$ 291,430	$ 209,948
Marketable securities	845,535	267,166
Accounts receivable	19,320	25,155
Unbilled accounts receivable	2,595	11,875
Inventory	35,253	21,817
Prepaid expenses and other current assets	33,532	18,064
Total current assets	1,227,665	554,025
Marketable securities	55,675	557,529
Property and equipment, net	33,454	30,700
Operating lease right-of-use assets, net	83,917	90,162
Restricted cash	5,193	5,171
Equity investment	27,789
Other assets	24,699	14,638
Total assets	1,458,392	1,252,225
Current liabilities:
Accounts payable	4,233	8,333
Accrued expenses	120,763	121,829
Current portion of operating lease liabilities	10,116	8,093
Current portion of deferred revenue	4,629	11,510
Current portion of liabilities related to the sale of future royalties and revenues	20,479
Current portion of term loan	15,290
Total current liabilities	175,510	149,765
Operating lease liabilities, net of current portion	95,495	103,315
Deferred revenue, net of current portion	11,995	25,066
Liabilities related to the sale of future royalties and revenues, net of current portion	403,174
Term loan, net of current portion	123,060
Other long-term liabilities	8,851	3,344
Total liabilities	818,085	281,490
Commitments and Contingencies (Note 15)
Stockholders' equity:
Preferred stock, $0.001 par value; 5,000,000 shares authorized; no shares issued and outstanding
Common stock, $0.001 par value; 120,000,000 shares authorized; 59,808,492 and 59,141,086 shares issued and outstanding at September 30, 2022 and December 31, 2021, respectively	60	59
Additional paid-in capital	2,329,385	2,250,250
Accumulated other comprehensive loss	(14,826)	(4,133)
Accumulated deficit	(1,674,312)	(1,275,441)
Total stockholders' equity	640,307	970,735
Total liabilities and stockholders' equity	$ 1,458,392	$ 1,252,225