Condensed Consolidated Balance Sheets - USD ($) $ in Thousands	Jun. 30, 2022	Dec. 31, 2021
Current assets:
Cash and cash equivalents	$ 173,399	$ 209,948
Marketable securities	679,712	267,166
Accounts receivable	27,123	25,155
Unbilled accounts receivable	2,287	11,875
Inventory	35,454	21,817
Prepaid expenses and other current assets	34,204	18,064
Total current assets	952,179	554,025
Marketable securities	94,048	557,529
Property and equipment, net	32,987	30,700
Operating lease right-of-use assets, net	86,033	90,162
Restricted cash	5,171	5,171
Other assets	22,028	14,638
Total assets	1,192,446	1,252,225
Current liabilities:
Accounts payable	15,053	8,333
Accrued expenses	119,282	121,829
Current portion of operating lease liabilities	9,435	8,093
Current portion of deferred revenue	9,478	11,510
Liability related to the sale of future royalties	5,512
Total current liabilities	158,760	149,765
Operating lease liabilities, net of current portion	98,160	103,315
Deferred revenue, net of current portion	12,661	25,066
Liability related to the sale of future royalties, net of current portion	165,742
Other long-term liabilities	9,373	3,344
Total liabilities	444,696	281,490
Commitments and Contingencies (Note 15)
Stockholders' equity:
Preferred stock, $0.001 par value; 5,000,000 shares authorized; no shares issued and outstanding
Common stock, $0.001 par value; 120,000,000 shares authorized; 59,688,295 and 59,141,086 shares issued and outstanding at June 30, 2022 and December 31, 2021, respectively	60	59
Additional paid-in capital	2,303,087	2,250,250
Accumulated other comprehensive loss	(14,248)	(4,133)
Accumulated deficit	(1,541,149)	(1,275,441)
Total stockholders' equity	747,750	970,735
Total liabilities and stockholders' equity	$ 1,192,446	$ 1,252,225