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Subsequent Events (Details) - Collaboration - USD ($)
$ / shares in Units, $ in Millions
1 Months Ended
Jul. 13, 2020
Oct. 15, 2019
Jul. 31, 2020
Oct. 31, 2019
Mar. 31, 2016
Sep. 30, 2020
Clementia            
Subsequent Events            
Non-refundable upfront payment received   $ 25.0        
Milestone payment received       $ 20.0    
Roche            
Subsequent Events            
Non-refundable upfront payment received         $ 45.0  
Eligible contingent option and milestone payments         $ 940.0  
Subsequent Event | Clementia            
Subsequent Events            
Milestone payment received     $ 20.0      
Subsequent Event | Roche            
Subsequent Events            
Upfront cash payment receivable           $ 675.0
Non-refundable upfront payment received $ 675.0          
Eligible contingent option and milestone payments $ 927.0          
Percentage of global development costs, Company (as a percent) 45.00%          
Percentage of global development costs, Roche (as a percent) 55.00%          
Subsequent Event | Private Placement | Roche            
Subsequent Events            
Purchase price $ 96.57          
Stock purchase agreement issued and sold 973,386          
Private placement purchase price $ 96.57          
Gross proceeds from issuance of private placement $ 94.0          
Number of shares agreed to be issued or sold under the share purchase agreement 62,133          
Additional gross proceeds to expiration or termination $ 6.0