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Collaboration and License Agreements - General Information (Details)
$ in Thousands
1 Months Ended 3 Months Ended 12 Months Ended
Oct. 15, 2019
USD ($)
item
Jun. 01, 2018
USD ($)
item
Oct. 31, 2019
USD ($)
Jun. 30, 2018
USD ($)
Mar. 31, 2018
USD ($)
Mar. 31, 2016
USD ($)
item
Mar. 31, 2020
USD ($)
item
Dec. 31, 2019
USD ($)
item
Mar. 31, 2019
USD ($)
Mar. 31, 2016
USD ($)
item
Dec. 31, 2019
USD ($)
Collaboration Agreements                      
Collaboration revenue             $ 6,167   $ 730    
Current portion of deferred revenue             $ 8,690 $ 6,160     $ 6,160
Roche | Revenue, Remaining Performance Obligation, Expected Timing of Satisfaction, Start Date [Axis]: 2019-07-01                      
Collaboration Agreements                      
Research and development services, performance period             5 years        
Collaboration | Clementia                      
Collaboration Agreements                      
Non-refundable upfront payment received $ 25,000                    
Eligible milestone payments 510,000                    
Cash milestone payment 20,000                    
Milestone other payment 490,000                    
Purchase specified manufacturing inventory $ 1,500                    
Number of performance obligations | item 3                    
Purchase of existing manufacturing inventory $ 1,200                    
Purchase of in-process manufacturing inventory $ 300                    
Number of material promises | item 4                    
Initial cash payment $ 46,500                    
Collaboration revenue             $ 0   0   46,200
Deferred revenue             0   0    
Collaboration | C Stone                      
Collaboration Agreements                      
Non-refundable upfront payment received   $ 40,000                  
Eligible milestone payments   $ 346,000                  
Number of performance obligations | item   3                  
Licensed product term from first commercial sale   12 years                  
Number of materials components | item   2                  
Number of option rights to obtain exclusive license | item   3                  
Number of potential collaboration programs | item   3                  
Number of material promises | item   6                  
Number of collaboration programs with exclusive commercialization rights for licensed products | item   3                  
Initial cash payment   $ 40,000                  
Collaboration revenue             2,134        
Deferred revenue             $ 0 $ 0     $ 0
Revenue recognized, change in contract liability                 40,000    
Collaboration | C Stone | Development and regulatory milestones                      
Collaboration Agreements                      
Eligible milestone payments   118,500                  
Number of potential collaboration programs | item             1        
Collaboration revenue             $ 2,000        
Collaboration | C Stone | Sales-based milestones                      
Collaboration Agreements                      
Eligible milestone payments   $ 227,500                  
Collaboration | Roche                      
Collaboration Agreements                      
Non-refundable upfront payment received           $ 45,000          
Number of small molecule therapeutics targeting kinases | item           5       5  
Number of option rights to obtain exclusive license | item           5       5  
Number of potential collaboration programs | item           4   4      
Initial cash payment         $ 45,000 $ 45,000          
Collaboration revenue             575   730    
Deferred revenue             45,500        
Total eligible contingent option fees and milestone payments           940,000       $ 940,000  
Eligible option fees and milestones prior to licensing for all potential collaboration programs           $ 190,000          
Current portion of deferred revenue             8,700        
Achieved research milestone payment received which will be recognized over period of performance     $ 8,000 $ 10,000              
Revenue recognized, change in contract liability             $ 989   $ 987    
Collaboration | Roche | Prior To Exercise License Right Option                      
Collaboration Agreements                      
Written termination notice period           120 days          
Collaboration | Roche | Exercise Of License Right Option                      
Collaboration Agreements                      
Number of collaboration programs with exclusive commercialization rights for licensed products | item           2          
Number of collaboration programs with specified commercial rights for each party | item           2          
Collaboration | Roche | Exercise Of License Option Product Not Commercially Sold                      
Collaboration Agreements                      
Written termination notice period           120 days          
Collaboration | Roche | Exercise Of License Option Product Commercially Sold                      
Collaboration Agreements                      
Written termination notice period           180 days