3.20.1 html 165 345 1 false 53 0 false 7 false false R1.htm 00090 - Document - Document and Entity Information Sheet http://www.blueprintmedicines.com/role/DocumentDocumentAndEntityInformation Document and Entity Information Cover 1 false false R2.htm 00100 - Statement - Condensed Consolidated Balance Sheets Sheet http://www.blueprintmedicines.com/role/StatementCondensedConsolidatedBalanceSheets Condensed Consolidated Balance Sheets Statements 2 false false R3.htm 00105 - Statement - Condensed Consolidated Balance Sheets (Parenthetical) Sheet http://www.blueprintmedicines.com/role/StatementCondensedConsolidatedBalanceSheetsParenthetical Condensed Consolidated Balance Sheets (Parenthetical) Statements 3 false false R4.htm 00200 - Statement - Condensed Consolidated Statements of Operations and Comprehensive Loss Sheet http://www.blueprintmedicines.com/role/StatementCondensedConsolidatedStatementsOfOperationsAndComprehensiveLoss Condensed Consolidated Statements of Operations and Comprehensive Loss Statements 4 false false R5.htm 00300 - Statement - Condensed Consolidated Statements of Stockholders' Equity Sheet http://www.blueprintmedicines.com/role/StatementCondensedConsolidatedStatementsOfStockholdersEquity Condensed Consolidated Statements of Stockholders' Equity Statements 5 false false R6.htm 00400 - Statement - Condensed Consolidated Statements of Cash Flows Sheet http://www.blueprintmedicines.com/role/StatementCondensedConsolidatedStatementsOfCashFlows Condensed Consolidated Statements of Cash Flows Statements 6 false false R7.htm 00405 - Statement - Condensed Consolidated Statements of Cash Flows (Parenthetical) Sheet http://www.blueprintmedicines.com/role/StatementCondensedConsolidatedStatementsOfCashFlowsParenthetical Condensed Consolidated Statements of Cash Flows (Parenthetical) Statements 7 false false R8.htm 10101 - Disclosure - Nature of Business Sheet http://www.blueprintmedicines.com/role/DisclosureNatureOfBusiness Nature of Business Notes 8 false false R9.htm 10201 - Disclosure - Summary of Significant Accounting Policies and Recent Accounting Pronouncements Sheet http://www.blueprintmedicines.com/role/DisclosureSummaryOfSignificantAccountingPoliciesAndRecentAccountingPronouncements Summary of Significant Accounting Policies and Recent Accounting Pronouncements Notes 9 false false R10.htm 10301 - Disclosure - Cash Equivalents and Investments Sheet http://www.blueprintmedicines.com/role/DisclosureCashEquivalentsAndInvestments Cash Equivalents and Investments Notes 10 false false R11.htm 10401 - Disclosure - Fair Value of Financial Instruments Sheet http://www.blueprintmedicines.com/role/DisclosureFairValueOfFinancialInstruments Fair Value of Financial Instruments Notes 11 false false R12.htm 10501 - Disclosure - Product Revenue Reserves and Allowances Sheet http://www.blueprintmedicines.com/role/DisclosureProductRevenueReservesAndAllowances Product Revenue Reserves and Allowances Notes 12 false false R13.htm 10601 - Disclosure - Inventory Sheet http://www.blueprintmedicines.com/role/DisclosureInventory Inventory Notes 13 false false R14.htm 10701 - Disclosure - Restricted Cash Sheet http://www.blueprintmedicines.com/role/DisclosureRestrictedCash Restricted Cash Notes 14 false false R15.htm 10801 - Disclosure - Property and Equipment, Net Sheet http://www.blueprintmedicines.com/role/DisclosurePropertyAndEquipmentNet Property and Equipment, Net Notes 15 false false R16.htm 10901 - Disclosure - Accrued Expenses Sheet http://www.blueprintmedicines.com/role/DisclosureAccruedExpenses Accrued Expenses Notes 16 false false R17.htm 11001 - Disclosure - Collaboration and License Agreements Sheet http://www.blueprintmedicines.com/role/DisclosureCollaborationAndLicenseAgreements Collaboration and License Agreements Notes 17 false false R18.htm 11101 - Disclosure - Stock-based Compensation Sheet http://www.blueprintmedicines.com/role/DisclosureStockBasedCompensation Stock-based Compensation Notes 18 false false R19.htm 11201 - Disclosure - Net Loss per Share Sheet http://www.blueprintmedicines.com/role/DisclosureNetLossPerShare Net Loss per Share Notes 19 false false R20.htm 11301 - Disclosure - Income Taxes Sheet http://www.blueprintmedicines.com/role/DisclosureIncomeTaxes Income Taxes Notes 20 false false R21.htm 11401 - Disclosure - Leases Sheet http://www.blueprintmedicines.com/role/DisclosureLeases Leases Notes 21 false false R22.htm 11501 - Disclosure - Commitments Sheet http://www.blueprintmedicines.com/role/DisclosureCommitments Commitments Notes 22 false false R23.htm 11601 - Disclosure - Subsequent Events Sheet http://www.blueprintmedicines.com/role/DisclosureSubsequentEvents Subsequent Events Notes 23 false false R24.htm 20202 - Disclosure - Summary of Significant Accounting Policies and Recent Accounting Pronouncements (Policies) Sheet http://www.blueprintmedicines.com/role/DisclosureSummaryOfSignificantAccountingPoliciesAndRecentAccountingPronouncementsPolicies Summary of Significant Accounting Policies and Recent Accounting Pronouncements (Policies) Policies http://www.blueprintmedicines.com/role/DisclosureSummaryOfSignificantAccountingPoliciesAndRecentAccountingPronouncements 24 false false R25.htm 30303 - Disclosure - Cash Equivalents and Investments (Tables) Sheet http://www.blueprintmedicines.com/role/DisclosureCashEquivalentsAndInvestmentsTables Cash Equivalents and Investments (Tables) Tables http://www.blueprintmedicines.com/role/DisclosureCashEquivalentsAndInvestments 25 false false R26.htm 30403 - Disclosure - Fair Value of Financial Instruments (Tables) Sheet http://www.blueprintmedicines.com/role/DisclosureFairValueOfFinancialInstrumentsTables Fair Value of Financial Instruments (Tables) Tables http://www.blueprintmedicines.com/role/DisclosureFairValueOfFinancialInstruments 26 false false R27.htm 30503 - Disclosure - Product Revenue Reserves and Allowances (Tables) Sheet http://www.blueprintmedicines.com/role/DisclosureProductRevenueReservesAndAllowancesTables Product Revenue Reserves and Allowances (Tables) Tables http://www.blueprintmedicines.com/role/DisclosureProductRevenueReservesAndAllowances 27 false false R28.htm 30603 - Disclosure - Inventory (Tables) Sheet http://www.blueprintmedicines.com/role/DisclosureInventoryTables Inventory (Tables) Tables http://www.blueprintmedicines.com/role/DisclosureInventory 28 false false R29.htm 30803 - Disclosure - Property and Equipment, Net (Tables) Sheet http://www.blueprintmedicines.com/role/DisclosurePropertyAndEquipmentNetTables Property and Equipment, Net (Tables) Tables http://www.blueprintmedicines.com/role/DisclosurePropertyAndEquipmentNet 29 false false R30.htm 30903 - Disclosure - Accrued Expenses (Tables) Sheet http://www.blueprintmedicines.com/role/DisclosureAccruedExpensesTables Accrued Expenses (Tables) Tables http://www.blueprintmedicines.com/role/DisclosureAccruedExpenses 30 false false R31.htm 31003 - Disclosure - Collaboration and License Agreements (Tables) Sheet http://www.blueprintmedicines.com/role/DisclosureCollaborationAndLicenseAgreementsTables Collaboration and License Agreements (Tables) Tables http://www.blueprintmedicines.com/role/DisclosureCollaborationAndLicenseAgreements 31 false false R32.htm 31103 - Disclosure - Stock-based Compensation (Tables) Sheet http://www.blueprintmedicines.com/role/DisclosureStockBasedCompensationTables Stock-based Compensation (Tables) Tables http://www.blueprintmedicines.com/role/DisclosureStockBasedCompensation 32 false false R33.htm 31203 - Disclosure - Net Loss per Share (Tables) Sheet http://www.blueprintmedicines.com/role/DisclosureNetLossPerShareTables Net Loss per Share (Tables) Tables http://www.blueprintmedicines.com/role/DisclosureNetLossPerShare 33 false false R34.htm 31403 - Disclosure - Leases (Tables) Sheet http://www.blueprintmedicines.com/role/DisclosureLeasesTables Leases (Tables) Tables http://www.blueprintmedicines.com/role/DisclosureLeases 34 false false R35.htm 40101 - Disclosure - Nature of Business - Sale of Stock (Details) Sheet http://www.blueprintmedicines.com/role/DisclosureNatureOfBusinessSaleOfStockDetails Nature of Business - Sale of Stock (Details) Details 35 false false R36.htm 40102 - Disclosure - Nature of Business - Cash, Cash Equivalents and Investments (Details) Sheet http://www.blueprintmedicines.com/role/DisclosureNatureOfBusinessCashCashEquivalentsAndInvestmentsDetails Nature of Business - Cash, Cash Equivalents and Investments (Details) Details 36 false false R37.htm 40202 - Disclosure - Summary of Significant Accounting Policies and Recent Accounting Pronouncements - New Accounting Pronouncements (Details) Sheet http://www.blueprintmedicines.com/role/DisclosureSummaryOfSignificantAccountingPoliciesAndRecentAccountingPronouncementsNewAccountingPronouncementsDetails Summary of Significant Accounting Policies and Recent Accounting Pronouncements - New Accounting Pronouncements (Details) Details 37 false false R38.htm 40301 - Disclosure - Cash Equivalents and Investments - Tabular Disclosure - Cash Equivalents (Details) Sheet http://www.blueprintmedicines.com/role/DisclosureCashEquivalentsAndInvestmentsTabularDisclosureCashEquivalentsDetails Cash Equivalents and Investments - Tabular Disclosure - Cash Equivalents (Details) Details 38 false false R39.htm 40302 - Disclosure - Cash Equivalents and Investments - Tabular Disclosure - Investments, Available-for-sale (Details) Sheet http://www.blueprintmedicines.com/role/DisclosureCashEquivalentsAndInvestmentsTabularDisclosureInvestmentsAvailableForSaleDetails Cash Equivalents and Investments - Tabular Disclosure - Investments, Available-for-sale (Details) Details 39 false false R40.htm 40303 - Disclosure - Cash Equivalents and Investments - Tabular Disclosure - Total (Details) Sheet http://www.blueprintmedicines.com/role/DisclosureCashEquivalentsAndInvestmentsTabularDisclosureTotalDetails Cash Equivalents and Investments - Tabular Disclosure - Total (Details) Details 40 false false R41.htm 40304 - Disclosure - Cash Equivalents and Investments - Unrealized Loss Position (Details) Sheet http://www.blueprintmedicines.com/role/DisclosureCashEquivalentsAndInvestmentsUnrealizedLossPositionDetails Cash Equivalents and Investments - Unrealized Loss Position (Details) Details 41 false false R42.htm 40305 - Disclosure - Cash Equivalents and Investments - Remaining Maturities (Details) Sheet http://www.blueprintmedicines.com/role/DisclosureCashEquivalentsAndInvestmentsRemainingMaturitiesDetails Cash Equivalents and Investments - Remaining Maturities (Details) Details 42 false false R43.htm 40401 - Disclosure - Fair Value of Financial Instruments (Details) Sheet http://www.blueprintmedicines.com/role/DisclosureFairValueOfFinancialInstrumentsDetails Fair Value of Financial Instruments (Details) Details http://www.blueprintmedicines.com/role/DisclosureFairValueOfFinancialInstrumentsTables 43 false false R44.htm 40501 - Disclosure - Product Revenue Reserves and Allowances - Product Revenue (Details) Sheet http://www.blueprintmedicines.com/role/DisclosureProductRevenueReservesAndAllowancesProductRevenueDetails Product Revenue Reserves and Allowances - Product Revenue (Details) Details 44 false false R45.htm 40502 - Disclosure - Product Revenue Reserves and Allowances - Product Revenue Allowance - Roll Forward (Details) Sheet http://www.blueprintmedicines.com/role/DisclosureProductRevenueReservesAndAllowancesProductRevenueAllowanceRollForwardDetails Product Revenue Reserves and Allowances - Product Revenue Allowance - Roll Forward (Details) Details 45 false false R46.htm 40503 - Disclosure - Product Revenue Reserves and Allowances - Product Revenue Allowance - Location (Details) Sheet http://www.blueprintmedicines.com/role/DisclosureProductRevenueReservesAndAllowancesProductRevenueAllowanceLocationDetails Product Revenue Reserves and Allowances - Product Revenue Allowance - Location (Details) Details 46 false false R47.htm 40601 - Disclosure - Inventory - Capitalized (Details) Sheet http://www.blueprintmedicines.com/role/DisclosureInventoryCapitalizedDetails Inventory - Capitalized (Details) Details 47 false false R48.htm 40602 - Disclosure - Inventory - Write-down (Details) Sheet http://www.blueprintmedicines.com/role/DisclosureInventoryWriteDownDetails Inventory - Write-down (Details) Details 48 false false R49.htm 40701 - Disclosure - Restricted Cash (Details) Sheet http://www.blueprintmedicines.com/role/DisclosureRestrictedCashDetails Restricted Cash (Details) Details http://www.blueprintmedicines.com/role/DisclosureRestrictedCash 49 false false R50.htm 40801 - Disclosure - Property and Equipment, Net - Estimated Useful Lives (Details) Sheet http://www.blueprintmedicines.com/role/DisclosurePropertyAndEquipmentNetEstimatedUsefulLivesDetails Property and Equipment, Net - Estimated Useful Lives (Details) Details 50 false false R51.htm 40802 - Disclosure - Property and Equipment, Net - Property and Equipment and Related Accumulated Depreciation (Details) Sheet http://www.blueprintmedicines.com/role/DisclosurePropertyAndEquipmentNetPropertyAndEquipmentAndRelatedAccumulatedDepreciationDetails Property and Equipment, Net - Property and Equipment and Related Accumulated Depreciation (Details) Details 51 false false R52.htm 40803 - Disclosure - Property and Equipment, Net - Depreciation Expense (Details) Sheet http://www.blueprintmedicines.com/role/DisclosurePropertyAndEquipmentNetDepreciationExpenseDetails Property and Equipment, Net - Depreciation Expense (Details) Details 52 false false R53.htm 40901 - Disclosure - Accrued Expenses (Details) Sheet http://www.blueprintmedicines.com/role/DisclosureAccruedExpensesDetails Accrued Expenses (Details) Details http://www.blueprintmedicines.com/role/DisclosureAccruedExpensesTables 53 false false R54.htm 41001 - Disclosure - Collaboration and License Agreements - General Information (Details) Sheet http://www.blueprintmedicines.com/role/DisclosureCollaborationAndLicenseAgreementsGeneralInformationDetails Collaboration and License Agreements - General Information (Details) Details 54 false false R55.htm 41002 - Disclosure - Collaboration and License Agreements - Manufacturing Services (Details) Sheet http://www.blueprintmedicines.com/role/DisclosureCollaborationAndLicenseAgreementsManufacturingServicesDetails Collaboration and License Agreements - Manufacturing Services (Details) Details 55 false false R56.htm 41003 - Disclosure - Collaboration and License Agreements - Revenue Recognized - CStone (Details) Sheet http://www.blueprintmedicines.com/role/DisclosureCollaborationAndLicenseAgreementsRevenueRecognizedCstoneDetails Collaboration and License Agreements - Revenue Recognized - CStone (Details) Details 56 false false R57.htm 41004 - Disclosure - Collaboration and License Agreements - Contract Assets - CStone (Details) Sheet http://www.blueprintmedicines.com/role/DisclosureCollaborationAndLicenseAgreementsContractAssetsCstoneDetails Collaboration and License Agreements - Contract Assets - CStone (Details) Details 57 false false R58.htm 41005 - Disclosure - Collaboration and License Agreements - Revenue Recognized - Roche (Details) Sheet http://www.blueprintmedicines.com/role/DisclosureCollaborationAndLicenseAgreementsRevenueRecognizedRocheDetails Collaboration and License Agreements - Revenue Recognized - Roche (Details) Details 58 false false R59.htm 41101 - Disclosure - Stock-based Compensation - 2015 Stock Option and Incentive Plan (Details) Sheet http://www.blueprintmedicines.com/role/DisclosureStockBasedCompensation2015StockOptionAndIncentivePlanDetails Stock-based Compensation - 2015 Stock Option and Incentive Plan (Details) Details 59 false false R60.htm 41102 - Disclosure - Stock-based Compensation - Stock Options (Details) Sheet http://www.blueprintmedicines.com/role/DisclosureStockBasedCompensationStockOptionsDetails Stock-based Compensation - Stock Options (Details) Details 60 false false R61.htm 41103 - Disclosure - Stock-based Compensation - Restricted Stock Units (Details) Sheet http://www.blueprintmedicines.com/role/DisclosureStockBasedCompensationRestrictedStockUnitsDetails Stock-based Compensation - Restricted Stock Units (Details) Details 61 false false R62.htm 41104 - Disclosure - Stock-based Compensation - Unrecognized Compensation Costs (Details) Sheet http://www.blueprintmedicines.com/role/DisclosureStockBasedCompensationUnrecognizedCompensationCostsDetails Stock-based Compensation - Unrecognized Compensation Costs (Details) Details 62 false false R63.htm 41105 - Disclosure - Stock-based Compensation - 2020 Inducement Plan (Details) Sheet http://www.blueprintmedicines.com/role/DisclosureStockBasedCompensation2020InducementPlanDetails Stock-based Compensation - 2020 Inducement Plan (Details) Details 63 false false R64.htm 41106 - Disclosure - Stock-based Compensation - Employee Stock Purchase Plan (Details) Sheet http://www.blueprintmedicines.com/role/DisclosureStockBasedCompensationEmployeeStockPurchasePlanDetails Stock-based Compensation - Employee Stock Purchase Plan (Details) Details 64 false false R65.htm 41107 - Disclosure - Stock-based Compensation - Stock-based Compensation Expense (Details) Sheet http://www.blueprintmedicines.com/role/DisclosureStockBasedCompensationStockBasedCompensationExpenseDetails Stock-based Compensation - Stock-based Compensation Expense (Details) Details 65 false false R66.htm 41201 - Disclosure - Net Loss per Share (Details) Sheet http://www.blueprintmedicines.com/role/DisclosureNetLossPerShareDetails Net Loss per Share (Details) Details http://www.blueprintmedicines.com/role/DisclosureNetLossPerShareTables 66 false false R67.htm 41301 - Disclosure - Income Taxes (Details) Sheet http://www.blueprintmedicines.com/role/DisclosureIncomeTaxesDetails Income Taxes (Details) Details http://www.blueprintmedicines.com/role/DisclosureIncomeTaxes 67 false false R68.htm 41401 - Disclosure - Leases - General Information (Details) Sheet http://www.blueprintmedicines.com/role/DisclosureLeasesGeneralInformationDetails Leases - General Information (Details) Details 68 false false R69.htm 41402 - Disclosure - Leases - Components of Lease Expense (Details) Sheet http://www.blueprintmedicines.com/role/DisclosureLeasesComponentsOfLeaseExpenseDetails Leases - Components of Lease Expense (Details) Details 69 false false R70.htm 41403 - Disclosure - Leases - Cash Flow Information (Details) Sheet http://www.blueprintmedicines.com/role/DisclosureLeasesCashFlowInformationDetails Leases - Cash Flow Information (Details) Details 70 false false R71.htm 41404 - Disclosure - Leases - Weighted Average Remaining Lease-term and Weighted Average Discount Rate (Details) Sheet http://www.blueprintmedicines.com/role/DisclosureLeasesWeightedAverageRemainingLeaseTermAndWeightedAverageDiscountRateDetails Leases - Weighted Average Remaining Lease-term and Weighted Average Discount Rate (Details) Details 71 false false R72.htm 41501 - Disclosure - Commitments (Details) Sheet http://www.blueprintmedicines.com/role/DisclosureCommitmentsDetails Commitments (Details) Details http://www.blueprintmedicines.com/role/DisclosureCommitments 72 false false All Reports Book All Reports bpmc-20200506x10q.htm bpmc-20200331xex10d1.htm bpmc-20200331xex31d1.htm bpmc-20200331xex31d2.htm bpmc-20200331xex32d1.htm bpmc-20200331xex3d1.htm bpmc-20200506.xsd bpmc-20200506_cal.xml bpmc-20200506_def.xml bpmc-20200506_lab.xml bpmc-20200506_pre.xml http://fasb.org/us-gaap/2019-01-31 http://xbrl.sec.gov/dei/2019-01-31 http://fasb.org/srt/2019-01-31 true true