Organization and Summary of Significant Accounting Policies - Additional Information (Detail)					1 Months Ended	12 Months Ended
	May 26, 2021 USD ($)	Mar. 12, 2021 USD ($) Investment	Jun. 29, 2018 USD ($)	Oct. 14, 2016 USD ($)	Apr. 30, 2021 USD ($)	Mar. 31, 2021 USD ($) Investment Customer	Mar. 31, 2020 USD ($) Customer	Mar. 31, 2019 USD ($) Customer	Dec. 31, 2018 USD ($)	Jan. 31, 2015 USD ($)
Significant Accounting Policies [Line Items]
Accumulated deficit						$ (591,905,000)	$ (483,435,000)
Cash holdings and short-term investments						111,700,000
Aggregate principal amount of notes							25,000,000	$ 36,000,000
Restricted cash						9,024,000	9,017,000	$ 7,507,000
Allowance for doubtful accounts						$ 48,000	$ 111,000
Number of customer represent 10% or more of accounts receivable | Customer						1	1
Number of customer represent 10% or more of product sales | Customer						1	1	1
Stock-based compensation cost included in inventory						$ 0	$ 0
Property and equipment impairment losses						0	0	$ 0
Impairment losses						$ 0	$ 0	$ 0
Class of warrants description						As of March 31, 2021, the Company had one class of warrants to purchase ordinary shares outstanding which comprised warrants that were issued in December 2013 and August 2015 in connection with the establishment and subsequent increase of the Company’s then existing secured term loan facility.
Accounting Standards Update 2016-13 [Member]
Significant Accounting Policies [Line Items]
Change in accounting principle, adopted						true
Change in accounting principle, adoption date						Apr. 01, 2020
Change in accounting principle, immaterial effect						true
Accounting Standards Update 2018-14 [Member]
Significant Accounting Policies [Line Items]
Change in accounting principle, adopted						true
Change in accounting principle, adoption date						Apr. 01, 2020
Change in accounting principle, immaterial effect						true
Customer Relationships [Member]
Significant Accounting Policies [Line Items]
Intangible assets amortization over estimated useful life						5 years
Brands Associated with Acquired Cell Lines [Member]
Significant Accounting Policies [Line Items]
Intangible assets amortization over estimated useful life						40 years
Product Licenses [Member]
Significant Accounting Policies [Line Items]
Intangible assets amortization over estimated useful life						10 years
Other Intangibles [Member]
Significant Accounting Policies [Line Items]
Intangible assets amortization over estimated useful life						7 years
Distribution and Supply Agreement [Member]
Significant Accounting Policies [Line Items]
Milestone amount receivable upon fulfillment of achievement										$ 59,000,000.0
Minimum [Member]
Significant Accounting Policies [Line Items]
Plant, machinery and equipment useful life						4 years
Maximum [Member]
Significant Accounting Policies [Line Items]
Plant, machinery and equipment useful life						6 years
Plant, Machinery and Equipment [Member] | Minimum [Member]
Significant Accounting Policies [Line Items]
Plant, machinery and equipment useful life						4 years
Plant, Machinery and Equipment [Member] | Maximum [Member]
Significant Accounting Policies [Line Items]
Plant, machinery and equipment useful life						25 years
Credit Concentration Risk [Member] | Accounts Receivable [Member]
Significant Accounting Policies [Line Items]
Concentration risk percentage						74.00%	70.00%
Security For Property Rental Obligations of Subsidiary [Member]
Significant Accounting Policies [Line Items]
Restricted cash						$ 324,000	$ 317,000
Senior Secured Notes Due 2023 [Member] | Cash Reserve Account Held by Collateral Agent [Member]
Significant Accounting Policies [Line Items]
Restricted cash						$ 8,700,000	$ 8,700,000
4.75% Convertible Notes due 2026 [Member] | Subsequent Event [Member]
Significant Accounting Policies [Line Items]
Aggregate principal amount of notes	$ 95,000,000
Debt instrument, interest rate	4.75%
Secured Notes [Member]
Significant Accounting Policies [Line Items]
Aggregate principal amount of notes			$ 36,000,000	$ 84,000,000
Debt instrument, interest rate						12.00%	12.00%
Debt instrument one-time consent payment									$ 3,900,000
CSAM [Member]
Significant Accounting Policies [Line Items]
Number of short-term funds invested | Investment		2				2
Short-term investment held-to-maturity, current						$ 53,200,000
Impairment recognized, related to one of the short term funds invested						$ 2,300,000
Payments for (proceeds from) short-term investments		$ 75,600,000
Aggregate investment in suspend redemptions		$ 110,350,000
CSAM [Member] | Subsequent Event [Member]
Significant Accounting Policies [Line Items]
Payments for (proceeds from) short-term investments					$ (18,500,000)
Product [Member] | Customer Concentration Risk [Member] | Sales [Member]
Significant Accounting Policies [Line Items]
Concentration risk percentage						60.00%	61.00%	60.00%
Ortho's [Member]
Significant Accounting Policies [Line Items]
Milestone revenue recognized							$ 1,050,000
Non-refundable milestone payment						$ 7,500,000
Ortho's [Member] | Letter Agreement [Member]
Significant Accounting Policies [Line Items]
Non-refundable milestone payment						$ 7,500,000
Commencing on receipt of specified regulatory approvals period						10 years
Ortho's [Member] | Maximum [Member]
Significant Accounting Policies [Line Items]
Additional milestone payments receivable upon achievement of regulatory milestones and commercial sales benchmarks						$ 60,000,000
Milestone payments receivable upon achievement of cumulative gross revenue hurdles						25,000,000
MosaiQ [Member]
Significant Accounting Policies [Line Items]
Revenue recognized for milestone represents payment in respect of development work						7,500,000
Revenue remaining performance obligation						$ 0
MosaiQ [Member] | Secured Notes [Member]
Significant Accounting Policies [Line Items]
Debt instrument subscribers rights to receive payment as percentage of net MosaiQ sales						3.40%