X0306 4 2021-04-30 0 0001596946 Quotient Ltd QTNT 0001605065 McDonough Brian 28 ESPLANADE ST HELIER Y9 JE2 3QA JERSEY 1 0 0 0 Ordinary Shares 2021-04-30 4 M 0 3846 A 55413 D Ordinary Shares 53040 I By the McDonough-McGuire Joint Revocable Trust Ordinary Shares Option (Right to buy) 8.00 2024-04-29 Ordinary Shares 10000 10000 D Options to purchase ordinary shares 2014-11-14 2022-08-30 Ordinary Shares 40029 40029 D Ordinary Shares Option (Right to buy) 9.95 2024-10-31 Ordinary Shares 5025 5025 D Ordinary Shares Option (Right to buy) 11.62 2025-10-31 Ordinary Shares 4303 4303 D Ordinary Shares Option (Right to buy) 5.73 2026-10-31 Ordinary Shares 8726 8726 D Ordinary Shares Option (Right to buy) 5.21 2027-10-31 Ordinary Shares 9597 9597 D Ordinary Shares Option (Right to buy) 6.41 2028-10-31 Ordinary Shares 6240 6240 D Ordinary Shares Option (Right to buy) 7.78 2029-10-31 Ordinary Shares 8158 8158 D Restricted Stock Units 2021-04-30 4 M 0 3846 0.00 D Ordinary Shares 3846 7693 D Ordinary Share Option (Right to Buy) 4.55 2030-10-31 Ordinary Shares 13611 13611 D All 10,000 options have vested and remain exercisable. The exercise price will be paid in pounds sterling, at GBP 0.91 per share. All 5,025 options have vested and remain exercisable. All 4,303 options have vested and remain exercisable. All 8,726 options have vested and remain exercisable. Restricted Stock Units convert into ordinary shares on a one-for-one basis. All 9,597 options have vested and remain exercisable. 4,160 options have vested and remain exercisable, and 2,080 options will vest on October 31, 2021. The Reporting Person and his spouse are Co-Trustees of their successors in trust, of the McDonough-McGuire Joint Revocable Trust, dated May 14, 2013. The Reporting Person disclaims beneficial ownership of these securities except to the extent of his pecuniary interest therein, and the inclusion of these ordinary shares in this report shall not be deemed an admission of beneficial ownership of all of the reported ordinary shares for purposes of Section 16 or for any other purpose. 2,719 options vested on October 31, 2020 and remain exercisable, and the remaining 5,439 options will vest in two equal annual installments on October 31, 2021 and October 31, 2022. On October 31, 2020, the Reporting Person was granted 15,385 restricted stock units, of which 7,692 have vested and have been exercised. The remaining 7,693 restricted stock units will vest in two equal installments on July 31, 2021 and October 31, 2021. The options vest and become exercisable on October 31, 2021. /s/ Brian McDonough 2021-05-03