X0306 4 2017-02-14 0 0000879169 INCYTE CORP INCY 0001596492 Hoppenot Herve 1801 AUGUSTINE CUT-OFF WILMINGTON DE 19803 1 1 0 1 Chairman / CEO President Common Stock 2017-02-14 4 A 0 17428 0.00 A 399234 D Common Stock 2017-02-24 4 F 0 8478 121.95 D 390756 D Common Stock 2017-02-24 4 F 0 32443 121.95 D 358313 D Represents shares acquired upon vesting of performance shares. Each performance share represented the right to receive one or more shares of common stock based on, and subject to, the achievement of certain clinical and revenue milestones as set forth in the Performance Share Award Agreement. The number of shares of common stock that the Reporting Person was entitled to receive ranged from 0% to 125% of the number of performance shares awarded. Performance share milestones were achieved at the 100% level. Includes an aggregate of 311,304 shares of common stock issuable pursuant to previously reported restricted stock units that have not vested. Represents shares withheld to satisfy tax withholding obligations with respect to vested performance shares. Represents shares withheld to satisfy tax withholding obligations due at settlement of restricted stock units previously reported in Table I as common stock. Includes an aggregate of 244,637 shares of common stock issuable pursuant to previously reported restricted stock units that have not vested. /s/ Herve Hoppenot 2017-02-28