Condensed Balance Sheets - USD ($) $ in Thousands	Mar. 31, 2022	Dec. 31, 2021
Current assets:
Cash and cash equivalents	$ 309,532	$ 427,879
Marketable securities	608,655	553,703
Prepaid and other current assets	9,244	10,880
Total current assets	927,431	992,462
Property and equipment, net	3,875	3,822
Right-of-use lease assets	5,439	5,158
Other assets	2,041	2,021
Total assets	938,786	1,003,463
Current liabilities:
Accounts payable	7,610	5,656
Accrued expenses and other current liabilities	27,632	25,300
Accrued compensation	6,363	12,503
Current portion of operating lease liabilities	3,961	3,630
Total current liabilities	45,566	47,089
Operating lease liabilities, long-term	1,873	1,949
Commitments and contingencies (Note 8)
Stockholders' equity:
Preferred stock, $0.0001 par value; 10,000,000 shares authorized at September 30, 2021 and December 31, 2020, zero shares outstanding at September 30, 2021 and December 31, 2020
Common stock, $0.0001 par value; 200,000,000 shares authorized at September 30, 2021 and December 31, 2020; 49,464,156 and 48,678,540 shares issued and outstanding at September 30, 2021 and December 31, 2020, respectively	5	5
Additional paid-in capital	1,487,906	1,472,421
Accumulated other comprehensive (loss)/income	(5,392)	(1,274)
Accumulated deficit	(591,172)	(516,727)
Total stockholders' equity	891,347	954,425
Total liabilities and stockholders’ equity	$ 938,786	$ 1,003,463