0001493152-24-019869.txt : 20240515
0001493152-24-019869.hdr.sgml : 20240515
20240515161530
ACCESSION NUMBER: 0001493152-24-019869
CONFORMED SUBMISSION TYPE: 13F-HR
PUBLIC DOCUMENT COUNT: 2
CONFORMED PERIOD OF REPORT: 20240331
FILED AS OF DATE: 20240515
DATE AS OF CHANGE: 20240515
EFFECTIVENESS DATE: 20240515
FILER:
COMPANY DATA:
COMPANY CONFORMED NAME: Opaleye Management Inc.
CENTRAL INDEX KEY: 0001595855
ORGANIZATION NAME:
IRS NUMBER: 205648796
STATE OF INCORPORATION: MA
FISCAL YEAR END: 1231
FILING VALUES:
FORM TYPE: 13F-HR
SEC ACT: 1934 Act
SEC FILE NUMBER: 028-15896
FILM NUMBER: 24950939
BUSINESS ADDRESS:
STREET 1: ONE BOSTON PLACE
STREET 2: SUITE 2600
CITY: BOSTON
STATE: MA
ZIP: 02108
BUSINESS PHONE: 617-904-9195
MAIL ADDRESS:
STREET 1: ONE BOSTON PLACE
STREET 2: SUITE 2600
CITY: BOSTON
STATE: MA
ZIP: 02108
13F-HR
1
primary_doc.xml
X0202
13F-HR
LIVE
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0001595855
XXXXXXXX
03-31-2024
03-31-2024
false
Opaleye Management Inc.
One Boston Place
Suite 2600
Boston
MA
02108
13F HOLDINGS REPORT
028-15896
000124513
801-78700
N
James Silverman
President
617-229-5085
/s/ James Silverman
Boston
MA
05-15-2024
0
51
436932852
INFORMATION TABLE
2
infotable.xml
4D MOLECULAR THERAPEUTICS INC
COM
35104E100
10963759
344123
SH
SOLE
344123
0
0
ACELYRIN INC
COM
00445A100
10665000
1580000
SH
SOLE
1580000
0
0
ALIGOS THERAPEUTICS INC
COM
01626L105
1597400
1630000
SH
SOLE
1630000
0
0
ALLAKOS INC
COM
01671P100
3068100
2435000
SH
SOLE
2435000
0
0
APPLIED THERAPEUTICS
COM
03828A101
3659875
1770000
SH
SOLE
1770000
0
0
ARVINAS INC
COM
04335A105
13622400
330000
SH
SOLE
330000
0
0
BIODESIX
COM
09075X108
764560
534657
SH
SOLE
534657
0
0
CATALYST PHARMACEUTICALS INC
COM
14888U101
16009419
1004355
SH
SOLE
1004355
0
0
CODEXIS INC
COM
192005106
10888800
3120000
SH
SOLE
3120000
0
0
COMPASS THERAPEUTICS INC
COM
20454B104
6276600
3170000
SH
SOLE
3170000
0
0
CONTEXT THERAPEUTICS INC
COM
21077P108
1529533
1108357
SH
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1108357
0
0
CRINETICS PHARMACEUTICALS INC
COM
22663K107
210000
210000
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DESIGN THERAPEUTICS INC
COM
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455543
113038
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0
0
EDGEWISE THERAPEUTICS INC
COM
28036F105
12129600
665000
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SOLE
665000
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0
ETON PHARMACEUTICALS INC
COM
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9171679
2445781
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FULCRUM THERAPEUTICS INC
COM
359616109
1227200
130000
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SOLE
130000
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GLAUKOS CORP
COM
377322102
808631
8576
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SOLE
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GOSSAMER BIO INC
COM
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2879329
2440109
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2440109
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0
GOSSAMER BIO INC
NOTE 5.000% 6/0
38341PAA0
3212928
8000000
PRN
SOLE
8000000
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HARROW HEALTH INC
COM
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51869538
3920600
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IBIO INC
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2760800
680000
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SOLE
680000
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0
INTELLIA THERAPEUTICS INC
COM
45826J105
7015050
255000
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SOLE
255000
0
0
IOVANCE BIOTHERAPEUTICS INC
COM
462260100
13293540
897000
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SOLE
897000
0
0
JASPER THERAPEUTICS INC
COM NEW
471871202
12788423
435573
SH
SOLE
435573
0
0
KEROS THERAPEUTICS INC
COM
492327101
24328500
367500
SH
SOLE
367500
0
0
LARIMAR THERAPEUTICS INC
COM
517125100
1323795
174413
SH
SOLE
174413
0
0
LIQUIDIA CORPORATION
COM NEW
53635D202
5826250
395000
SH
SOLE
395000
0
0
LYELL IMMUNOPHARMA INC
COM
55083R104
7481650
3355000
SH
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3355000
0
0
MORPHOSYS AG
SPONSORED ADS
617760202
1179100
65000
SH
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65000
0
0
NEWAMSTERDAM PHARMA COMPANY
ORDINARY SHARES
N62509109
7458926
315388
SH
SOLE
315388
0
0
NYXOAH S A
SHS
B6S7WD106
4316800
320000
SH
SOLE
320000
0
0
OCULAR THERAPEUTIX INC
COM
67576A100
60543556
6653138
SH
SOLE
6653138
0
0
PMV PHARMACEUTICALS INC
COM
69353Y103
802130
471481
SH
SOLE
471481
0
0
PRECIGEN INC
COM
74017N105
1373875
947500
SH
SOLE
947500
0
0
PROTAGONIST THERAPEUTICS INC
COM
74366E102
3260411
112700
SH
SOLE
112700
0
0
PROTARA THERAPEUTICS INC
COM STK
74365U107
10797302
2692594
SH
SOLE
2692594
0
0
REGULUS THERAPEUTICS INC
COM
75915K309
490487
170308
SH
SOLE
170308
0
0
RELMADA THERAPEUTICS INC
COM
75955J402
3529350
759000
SH
SOLE
759000
0
0
REPARE THERAPEUTICS iNC
COM
760273102
318212
67561
SH
SOLE
67561
0
0
REVANCE THERAPEUTICS INC
COM
761330109
3862200
785000
SH
SOLE
785000
0
0
RHYTHM PHARMACEUTICALS INC
COM
76243J105
22314950
515000
SH
SOLE
515000
0
0
SAVARA INC
COM
805111101
4257900
855000
SH
SOLE
855000
0
0
SYROS PHARMACEUTICALS INC
COM NEW
87184Q206
4212831
787545
SH
SOLE
787545
0
0
TG THERAPEUTICS INC
COM
88322Q108
34678800
2280000
SH
SOLE
2280000
0
0
TREVI THERAPEUTICS INC
COM
89532M101
9125250
2645000
SH
SOLE
2645000
0
0
UROGEN PHARMA LTD
COM
M96088105
4050000
270000
SH
SOLE
270000
0
0
VAXCYTE INC
COM
92243G108
5806350
85000
SH
SOLE
85000
0
0
VENTYX BIOSCIENCES INC
COM
92332V107
7067500
1285000
SH
SOLE
1285000
0
0
VERASTEM INC
COM NEW
92337C203
2494520
211400
SH
SOLE
211400
0
0
XOMA CORP DEL
COM NEW
98419J206
6012500
250000
SH
SOLE
250000
0
0
ZENTALIS PHARMACEUTICALS INC
COM
98943L107
3152000
200000
SH
SOLE
200000
0
0