The Securities and Exchange Commission has not necessarily reviewed the information in this filing and has not determined if it is accurate and complete.
The reader should not assume that the information is accurate and complete.

UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
FORM 13F

FORM 13F INFORMATION TABLE
OMB APPROVAL
OMB Number: 3235-0006
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COLUMN 1 COLUMN 2 COLUMN 3 COLUMN 4 COLUMN 5 COLUMN 6 COLUMN 7 COLUMN 8
VALUE SHRS OR SH/ PUT/ INVESTMENT OTHER VOTING AUTHORITY
NAME OF ISSUER TITLE OF CLASS CUSIP FIGI (to the nearest dollar) PRN AMT PRN CALL DISCRETION MANAGER SOLE SHARED NONE
ACADIA PHARMACEUTICALS INC COM 004225108   3,656,250 225,000 SH   SOLE   225,000 0 0
ALNYLAM PHARMACEUTICALS INC COM 02043Q107   5,467,500 22,500 SH   SOLE   22,500 0 0
ALNYLAM PHARMACEUTICALS INC COM 02043Q107   16,621,200 68,400 SH Put SOLE   68,400 0 0
AN2 THERAPEUTICS INC COM 037326105   471,562 219,331 SH   SOLE   219,331 0 0
ANNEXON INC COM 03589W102   1,519,000 310,000 SH   SOLE   310,000 0 0
ANNEXON INC COM 03589W102   1,051,050 214,500 SH Call SOLE   214,500 0 0
APELLIS PHARMACEUTICALS INC COM 03753U106   5,178,600 135,000 SH   SOLE   135,000 0 0
ARROWHEAD PHARMACEUTICALS IN COM 04280A100   909,650 35,000 SH   SOLE   35,000 0 0
ARVINAS INC COM 04335A105   1,996,500 75,000 SH   SOLE   75,000 0 0
ASCENDIS PHARMA A/S SPONSORED ADR 04351P101   11,827,010 86,721 SH   SOLE   86,721 0 0
ATYR PHARMA INC COM NEW 002120202   1,248,000 800,000 SH   SOLE   800,000 0 0
AXSOME THERAPEUTICS INC COM 05464T104   12,075,000 150,000 SH   SOLE   150,000 0 0
BIOHAVEN LTD COM G1110E107   17,007,900 490,000 SH   SOLE   490,000 0 0
BLUEPRINT MEDICINES CORP COM 09627Y109   4,311,200 40,000 SH   SOLE   40,000 0 0
BRIDGEBIO PHARMA INC COM 10806X102   3,546,200 140,000 SH   SOLE   140,000 0 0
CABALETTA BIO INC COM 12674W109   2,774,325 370,899 SH   SOLE   370,899 0 0
CG ONCOLOGY INC COM 156944100   8,208,200 260,000 SH   SOLE   260,000 0 0
CORBUS PHARMACEUTICALS HLDGS COM NEW 21833P301   7,918,750 175,000 SH   SOLE   175,000 0 0
CRINETICS PHARMACEUTICALS IN COM 22663K107   10,749,600 240,000 SH   SOLE   240,000 0 0
CYTOKINETICS INC COM NEW 23282W605   1,798,776 33,200 SH   SOLE   33,200 0 0
CYTOMX THERAPEUTICS INC COM 23284F105   366,000 300,000 SH   SOLE   300,000 0 0
ELEVATION ONCOLOGY INC COM 28623U101   1,620,000 600,000 SH   SOLE   600,000 0 0
ENGENE HOLDINGS INC COM 29286M105   3,963,721 420,331 SH   SOLE   420,331 0 0
HELIX ACQUISITION CORP II CL A ORD SHS G4444H101   3,066,000 300,000 SH   SOLE   300,000 0 0
IMMUNOVANT INC COM 45258J102   6,864,000 260,000 SH   SOLE   260,000 0 0
INSMED INC COM PAR $.01 457669307   4,355,000 65,000 SH   SOLE   65,000 0 0
INSMED INC COM PAR $.01 457669307   13,400,000 200,000 SH Call SOLE   200,000 0 0
INTELLIA THERAPEUTICS INC COM 45826J105   559,500 25,000 SH   SOLE   25,000 0 0
INTRA-CELLULAR THERAPIES INC COM 46116X101   684,900 10,000 SH   SOLE   10,000 0 0
JANUX THERAPEUTICS INC COM 47103J105   2,094,500 50,000 SH   SOLE   50,000 0 0
KORRO BIO INC COM 500946108   3,387,000 100,000 SH   SOLE   100,000 0 0
KRYSTAL BIOTECH INC COM 501147102   1,560,940 8,500 SH   SOLE   8,500 0 0
MACROGENICS INC COM 556099109   637,500 150,000 SH   SOLE   150,000 0 0
MOONLAKE IMMUNOTHERAPEUTICS CLASS A ORD 61559X104   13,191,000 300,000 SH   SOLE   300,000 0 0
NEUROGENE INC COM 64135M105   2,547,300 70,000 SH   SOLE   70,000 0 0
NUVATION BIO INC COM CL A 67080N101   3,358,000 1,150,000 SH   SOLE   1,150,000 0 0
OLEMA PHARMACEUTICALS INC COM 68062P106   5,951,000 550,000 SH   SOLE   550,000 0 0
PERSPECTIVE THERAPEUTICS INC COM NEW 46489V302   9,222,250 925,000 SH   SOLE   925,000 0 0
PHATHOM PHARMACEUTICALS INC COM 71722W107   6,180,000 600,000 SH   SOLE   600,000 0 0
PMV PHARMACEUTICALS INC COM 69353Y103   607,500 375,000 SH   SOLE   375,000 0 0
PROQR THRAPEUTICS N V SHS EURO N71542109   1,494,000 900,000 SH   SOLE   900,000 0 0
PTC THERAPEUTICS INC COM 69366J200   581,020 19,000 SH   SOLE   19,000 0 0
RAPT THERAPEUTICS INC COM 75382E109   915,000 300,000 SH Call SOLE   300,000 0 0
REGENXBIO INC COM 75901B107   1,989,000 170,000 SH   SOLE   170,000 0 0
REPLIMUNE GROUP INC COM 76029N106   4,050,000 450,000 SH   SOLE   450,000 0 0
REVANCE THERAPEUTICS INC COM 761330109   578,250 225,000 SH   SOLE   225,000 0 0
REZOLUTE INC COM NEW 76200L309   6,112,454 1,421,501 SH   SOLE   1,421,501 0 0
RHYTHM PHARMACEUTICALS INC COM 76243J105   4,819,951 117,388 SH   SOLE   117,388 0 0
ROIVANT SCIENCES LTD SHS G76279101   10,570,000 1,000,000 SH   SOLE   1,000,000 0 0
SAGIMET BIOSCIENCES INC COM SER A 786700104   769,500 225,000 SH   SOLE   225,000 0 0
SAREPTA THERAPEUTICS INC COM 803607100   8,690,000 55,000 SH   SOLE   55,000 0 0
SAVARA INC COM 805111101   4,235,030 1,050,876 SH   SOLE   1,050,876 0 0
SOLENO THERAPEUTICS INC COM 834203309   12,240,000 300,000 SH   SOLE   300,000 0 0
SPYRE THERAPEUTICS INC COM NEW 00773J202   5,883,072 250,237 SH   SOLE   250,237 0 0
SYNDAX PHARMACEUTICALS INC COM 87164F105   7,185,500 350,000 SH   SOLE   350,000 0 0
TARSUS PHARMACEUTICALS INC COM 87650L103   6,387,300 235,000 SH   SOLE   235,000 0 0
TAYSHA GENE THERAPIES INC COM SHS 877619106   2,800,000 1,250,000 SH   SOLE   1,250,000 0 0
TENAYA THERAPEUTICS INC COM 87990A106   4,185,000 1,350,000 SH   SOLE   1,350,000 0 0
TG THERAPEUTICS INC COM 88322Q108   8,895,000 500,000 SH   SOLE   500,000 0 0
VAXCYTE INC COM 92243G108   11,326,500 150,000 SH   SOLE   150,000 0 0
VIKING THERAPEUTICS INC COM 92686J106   5,035,950 95,000 SH   SOLE   95,000 0 0
VIRIDIAN THERAPEUTICS INC COM 92790C104   7,646,081 587,708 SH   SOLE   587,708 0 0
WAVE LIFE SCIENCES LTD SHS Y95308105   998,000 200,000 SH   SOLE   200,000 0 0