The Securities and Exchange Commission has not necessarily reviewed the information in this filing and has not determined if it is accurate and complete.
The reader should not assume that the information is accurate and complete.

UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
FORM 13F

FORM 13F INFORMATION TABLE
OMB APPROVAL
OMB Number: 3235-0006
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COLUMN 1 COLUMN 2 COLUMN 3 COLUMN 4 COLUMN 5 COLUMN 6 COLUMN 7 COLUMN 8
VALUE SHRS OR SH/ PUT/ INVESTMENT OTHER VOTING AUTHORITY
NAME OF ISSUER TITLE OF CLASS CUSIP FIGI (to the nearest dollar) PRN AMT PRN CALL DISCRETION MANAGER SOLE SHARED NONE
89BIO INC COM 282559103   1,523,000 100,000 SH Call SOLE   100,000 0 0
89BIO INC COM 282559103   3,046,000 200,000 SH   SOLE   200,000 0 0
AADI BIOSCIENCE INC COM 00032Q104   1,086,000 150,000 SH   SOLE   150,000 0 0
ACLARIS THERAPEUTICS INC COM 00461U105   3,438,000 425,000 SH   SOLE   425,000 0 0
AEROVATE THERAPEUTICS INC COM 008064107   4,034,000 200,000 SH   SOLE   200,000 0 0
AKERO THERAPEUTICS INC COM 00973Y108   10,522,000 275,000 SH   SOLE   275,000 0 0
ALPINE IMMUNE SCIENCES INC COM 02083G100   1,544,000 200,000 SH   SOLE   200,000 0 0
ALTIMMUNE INC COM NEW 02155H200   1,688,000 400,000 SH Call SOLE   400,000 0 0
AMBRX BIOPHARMA INC SPONSORED ADS 02290A102   2,230,000 250,000 SH   SOLE   250,000 0 0
AMICUS THERAPEUTICS INC COM 03152W109   5,268,000 475,000 SH   SOLE   475,000 0 0
AMYLYX PHARMACEUTICALS INC COM 03237H101   13,937,000 475,000 SH   SOLE   475,000 0 0
APELLIS PHARMACEUTICALS INC COM 03753U106   10,858,000 164,620 SH   SOLE   164,620 0 0
APELLIS PHARMACEUTICALS INC COM 03753U106   3,423,000 51,900 SH Call SOLE   51,900 0 0
ARCUS BIOSCIENCES INC COM 03969F109   1,368,000 75,000 SH   SOLE   75,000 0 0
ASCENDIS PHARMA A/S SPONSORED ADR 04351P101   11,794,000 110,000 SH   SOLE   110,000 0 0
ASTRIA THERAPEUTICS INC COM 04635X102   5,985,000 450,000 SH   SOLE   450,000 0 0
AVIDITY BIOSCIENCES INC COM 05370A108   1,919,000 125,000 SH   SOLE   125,000 0 0
AXSOME THERAPEUTICS INC COM 05464T104   13,878,000 225,000 SH   SOLE   225,000 0 0
BIOCRYST PHARMACEUTICALS INC COM 09058V103   2,294,000 275,000 SH   SOLE   275,000 0 0
BIOMEA FUSION INC COM 09077A106   3,721,000 120,000 SH   SOLE   120,000 0 0
BRIDGEBIO PHARMA INC COM 10806X102   415,000 25,000 SH   SOLE   25,000 0 0
COGENT BIOSCIENCES INC COM 19240Q201   5,935,000 550,000 SH   SOLE   550,000 0 0
CTI BIOPHARMA CORP COM 12648L601   8,400,000 2,000,000 SH   SOLE   2,000,000 0 0
DISC MEDICINE INC COM 254604101   2,119,000 100,000 SH   SOLE   100,000 0 0
FIBROGEN INC COM 31572Q808   494,000 26,500 SH   SOLE   26,500 0 0
FUSION PHARMACEUTICALS INC COM 36118A100   1,320,000 350,000 SH   SOLE   350,000 0 0
GERON CORP COM 374163103   977,000 450,000 SH   SOLE   450,000 0 0
IMMUNOGEN INC COM 45253H101   480,000 124,977 SH   SOLE   124,977 0 0
INCYTE CORP COM 45337C102   5,420,000 75,000 SH   SOLE   75,000 0 0
IOVANCE BIOTHERAPEUTICS INC COM 462260100   6,110,000 1,000,000 SH   SOLE   1,000,000 0 0
IVERIC BIO INC COM 46583P102   4,258,000 175,000 SH   SOLE   175,000 0 0
JOHNSON & JOHNSON COM 478160104   7,750,000 50,000 SH   SOLE   50,000 0 0
KARUNA THERAPEUTICS INC COM 48576A100   3,179,000 17,500 SH   SOLE   17,500 0 0
KEZAR LIFE SCIENCES INC COM 49372L100   548,000 175,000 SH   SOLE   175,000 0 0
MADRIGAL PHARMACEUTICALS INC COM 558868105   7,268,000 30,000 SH   SOLE   30,000 0 0
MIRATI THERAPEUTICS INC COM 60468T105   5,205,000 140,000 SH   SOLE   140,000 0 0
MOONLAKE IMMUNOTHERAPEUTICS CLASS A ORD 61559X104   4,171,000 195,000 SH   SOLE   195,000 0 0
PFIZER INC COM 717081103   8,160,000 200,000 SH   SOLE   200,000 0 0
PROMETHEUS BIOSCIENCES INC COM 74349U108   1,610,000 15,000 SH   SOLE   15,000 0 0
PROTAGONIST THERAPEUTICS INC COM 74366E102   5,175,000 225,000 SH   SOLE   225,000 0 0
RAIN ONCOLOGY INC COM 75082Q105   2,185,000 250,000 SH   SOLE   250,000 0 0
REATA PHARMACEUTICALS INC CL A 75615P103   6,364,000 70,000 SH   SOLE   70,000 0 0
REATA PHARMACEUTICALS INC CL A 75615P103   27,276,000 300,000 SH Call SOLE   300,000 0 0
REVANCE THERAPEUTICS INC COM 761330109   8,053,000 250,000 SH   SOLE   250,000 0 0
SAREPTA THERAPEUTICS INC COM 803607100   8,270,000 60,000 SH   SOLE   60,000 0 0
SAREPTA THERAPEUTICS INC COM 803607100   17,229,000 125,000 SH Call SOLE   125,000 0 0
SPDR SER TR S&P BIOTECH 78464A870   22,863,000 300,000 SH Call SOLE   300,000 0 0
SPRINGWORKS THERAPEUTICS INC COM 85205L107   710,000 27,578 SH   SOLE   27,578 0 0
SYNDAX PHARMACEUTICALS INC COM 87164F105   6,864,000 325,000 SH   SOLE   325,000 0 0
TARSUS PHARMACEUTICALS INC COM 87650L103   1,006,000 80,000 SH   SOLE   80,000 0 0
TG THERAPEUTICS INC COM 88322Q108   16,544,000 1,100,000 SH   SOLE   1,100,000 0 0
UNIQURE NV SHS N90064101   7,553,000 375,000 SH   SOLE   375,000 0 0
VANDA PHARMACEUTICALS INC COM 921659108   85,000 12,500 SH   SOLE   12,500 0 0
VAXCYTE INC COM 92243G108   8,433,000 225,000 SH   SOLE   225,000 0 0
VIKING THERAPEUTICS INC COM 92686J106   9,990,000 600,000 SH   SOLE   600,000 0 0
VIRIDIAN THERAPEUTICS INC COM 92790C104   4,452,000 175,000 SH   SOLE   175,000 0 0
X4 PHARMACEUTICALS INC COM 98420X103   740,000 850,000 SH   SOLE   850,000 0 0
XENON PHARMACEUTICALS INC COM 98420N105   7,158,000 200,000 SH   SOLE   200,000 0 0