The Securities and Exchange Commission has not necessarily reviewed the information in this filing and has not determined if it is accurate and complete.
The reader should not assume that the information is accurate and complete.

UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
FORM 13F

FORM 13F INFORMATION TABLE
OMB APPROVAL
OMB Number: 3235-0006
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COLUMN 1 COLUMN 2 COLUMN 3 COLUMN 4 COLUMN 5 COLUMN 6 COLUMN 7 COLUMN 8
VALUE SHRS OR SH/ PUT/ INVESTMENT OTHER VOTING AUTHORITY
NAME OF ISSUER TITLE OF CLASS CUSIP (x$1000) PRN AMT PRN CALL DISCRETION MANAGER SOLE SHARED NONE
9 METERS BIOPHARMA INC COM 654405109 1,948 3,250,000 SH   SOLE   3,250,000 0 0
AADI BIOSCIENCE INC COM 00032Q104 2,546 150,000 SH   SOLE   150,000 0 0
ACLARIS THERAPEUTICS INC COM 00461U105 2,155 125,000 SH   SOLE   125,000 0 0
AEGLEA BIOTHERAPEUTICS INC COM 00773J103 1,579 686,599 SH   SOLE   686,599 0 0
AMICUS THERAPEUTICS INC COM 03152W109 10,417 1,100,000 SH   SOLE   1,100,000 0 0
APELLIS PHARMACEUTICALS INC COM 03753U106 12,703 250,000 SH   SOLE   250,000 0 0
ARVINAS INC COM 04335A105 7,403 110,000 SH   SOLE   110,000 0 0
ASCENDIS PHARMA A/S SPONSORED ADR 04351P101 16,430 140,000 SH   SOLE   140,000 0 0
AXSOME THERAPEUTICS INC COM 05464T104 3,911 94,500 SH   SOLE   94,500 0 0
AXSOME THERAPEUTICS INC COM 05464T104 6,209 150,000 SH Put SOLE   150,000 0 0
BICYCLE THERAPEUTICS PLC SPONSORED ADS 088786108 4,388 100,000 SH   SOLE   100,000 0 0
BIOCRYST PHARMACEUTICALS INC COM 09058V103 5,691 350,000 SH   SOLE   350,000 0 0
CELLDEX THERAPEUTICS INC NEW COM NEW 15117B202 10,218 300,000 SH   SOLE   300,000 0 0
COGENT BIOSCIENCES INC COM 19240Q201 12,733 1,700,000 SH   SOLE   1,700,000 0 0
CRINETICS PHARMACEUTICALS IN COM 22663K107 1,866 85,000 SH   SOLE   85,000 0 0
CTI BIOPHARMA CORP COM 12648L601 6,071 1,300,000 SH   SOLE   1,300,000 0 0
DESIGN THERAPEUTICS INC COM 25056L103 3,230 200,000 SH   SOLE   200,000 0 0
IVERIC BIO INC COM 46583P102 7,574 450,000 SH   SOLE   450,000 0 0
KARUNA THERAPEUTICS INC COM 48576A100 7,607 60,000 SH   SOLE   60,000 0 0
KEZAR LIFE SCIENCES INC COM 49372L100 6,648 400,000 SH   SOLE   400,000 0 0
LARIMAR THERAPEUTICS INC COM 517125100 405 100,000 SH   SOLE   100,000 0 0
LEAP THERAPEUTICS INC COM 52187K101 1,739 993,714 SH   SOLE   993,714 0 0
MERUS N V COM N5749R100 10,576 400,000 SH   SOLE   400,000 0 0
MIRATI THERAPEUTICS INC COM 60468T105 1,644 20,000 SH   SOLE   20,000 0 0
PARDES BIOSCIENCES INC COM 69945Q105 614 85,000 SH   SOLE   85,000 0 0
PYXIS ONCOLOGY INC COMMON STOCK 747324101 303 75,000 SH   SOLE   75,000 0 0
RAPT THERAPEUTICS INC COM 75382E109 5,498 250,000 SH   SOLE   250,000 0 0
RELMADA THERAPEUTICS INC COM 75955J402 2,699 100,000 SH   SOLE   100,000 0 0
ROCKET PHARMACEUTICALS INC COM 77313F106 3,172 200,000 SH   SOLE   200,000 0 0
SAREPTA THERAPEUTICS INC COM 803607100 3,906 50,000 SH   SOLE   50,000 0 0
SATSUMA PHARMACEUTICALS INC COM 80405P107 1,800 473,562 SH   SOLE   473,562 0 0
SIERRA ONCOLOGY INC COM NEW 82640U404 10,416 325,000 SH   SOLE   325,000 0 0
SPDR S&P 500 ETF TR TR UNIT 78462F103 225,820 500,000 SH Put SOLE   500,000 0 0
SPDR SER TR S&P BIOTECH 78464A870 26,964 300,000 SH Call SOLE   300,000 0 0
SYNDAX PHARMACEUTICALS INC COM 87164F105 3,911 225,000 SH   SOLE   225,000 0 0
TARSUS PHARMACEUTICALS INC COM 87650L103 2,018 120,000 SH   SOLE   120,000 0 0
VAXCYTE INC COM 92243G108 7,245 300,000 SH   SOLE   300,000 0 0
VERONA PHARMA PLC SPONSORED ADS 925050106 3,743 750,000 SH   SOLE   750,000 0 0
VIRIDIAN THERAPEUTICS INC COM 92790C104 8,624 466,403 SH   SOLE   466,403 0 0
VISTAGEN THERAPEUTICS INC COM NEW 92840H202 1,631 1,315,154 SH   SOLE   1,315,154 0 0
XENON PHARMACEUTICALS INC COM 98420N105 3,057 100,000 SH   SOLE   100,000 0 0
ZENTALIS PHARMACEUTICALS INC COM 98943L107 3,691 80,000 SH   SOLE   80,000 0 0