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Note 5 - Equity (Details Textual)
12 Months Ended
Jan. 25, 2020
shares
Jan. 01, 2020
shares
Nov. 22, 2019
USD ($)
$ / shares
shares
Jan. 01, 2019
shares
Sep. 20, 2018
shares
Aug. 01, 2018
$ / shares
shares
May 09, 2018
USD ($)
$ / shares
shares
Apr. 03, 2018
USD ($)
$ / shares
shares
Dec. 31, 2019
USD ($)
$ / shares
shares
Dec. 31, 2018
USD ($)
$ / shares
shares
Mar. 31, 2018
$ / shares
shares
Jan. 29, 2018
USD ($)
$ / shares
shares
Dec. 31, 2017
$ / shares
shares
Class of Warrant or Right, Exercise Price of Warrants or Rights | $ / shares                 $ 1.45 $ 2.36     $ 5.17
Proceeds from Issuance of Common Stock | $                 $ 1,267,194 $ 15,389,518      
Stock Issued During Period, Shares, Issued for Services                 506,707 200,009      
Stock Issued During Period, Value, Issued for Services | $                 $ 469,588 $ 553,303      
Preferred Stock, Shares Authorized               10,000,000     10,000,000    
Preferred Stock, Par or Stated Value Per Share | $ / shares                 $ 0.001   $ 0.001    
Preferred Stock, Shares Outstanding, Ending Balance                 0        
Non-voting To Voting Common Stock, Conversion Ratio               1          
Common Stock, Shares Authorized               200,000,000 200,000,000 200,000,000 200,000,000    
Common Stock, Par or Stated Value Per Share | $ / shares               $ 0.001 $ 0.001 $ 0.001 $ 0.001    
Common Stock, Shares, Outstanding, Ending Balance                 19,263,841 15,239,148      
Class of Warrant or Right, Issued in Period                 3,611,504 3,166,492      
Class of Warrant or Right, Issued During Period, Exercise Price | $ / shares                 $ 0.47 $ 1.74      
Class of Warrant or Right, Exercised During Period                 34,615      
Class of Warrant or Right, Cancelled During Period                 15,385      
Share-based Compensation Arrangement by Share-based Payment Award, Options, Outstanding, Number, Ending Balance                 5,982,923 4,535,681     2,628,749
Share-based Compensation Arrangement by Share-based Payment Award, Expiration Period                 10 years        
Share-based Compensation Arrangement by Share-based Payment Award, Options, Outstanding, Weighted Average Exercise Price, Ending Balance | $ / shares                 $ 2.66 $ 3.31     $ 1.31
Share-based Compensation Arrangement by Share-based Payment Award, Options, Grants in Period, Gross                 1,744,300 2,034,525      
Share-based Compensation Arrangements by Share-based Payment Award, Options, Grants in Period, Weighted Average Exercise Price | $ / shares                 $ 1.48 $ 6.21      
Share-based Compensation Arrangement by Share-based Payment Award, Options, Forfeitures and Expirations in Period, Total                 297,058 127,593      
Share-based Compensation Arrangement by Share-based Payment Award, Options, Outstanding, Weighted Average Remaining Contractual Term                 7 years 164 days 7 years 270 days      
Share-based Payment Arrangement, Nonvested Award, Option, Cost Not yet Recognized, Amount | $                 $ 4.50        
Share-based Payment Arrangement, Expense | $                 3,500,000        
Graded Vesting Method [Member]                          
Share-based Payment Arrangement, Nonvested Award, Option, Cost Not yet Recognized, Amount | $                 4,300,000        
Cliff Vesting Method [Member]                          
Share-based Payment Arrangement, Nonvested Award, Option, Cost Not yet Recognized, Amount | $                 $ 200,000        
Share-based Payment Arrangement, Option [Member]                          
Share-based Payment Arrangement, Nonvested Award, Cost Not yet Recognized, Period for Recognition                 2 years        
Share-based Payment Arrangement, Expense | $                 $ 3,000,000        
Performance Shares [Member]                          
Share-based Payment Arrangement, Nonvested Award, Cost Not yet Recognized, Period for Recognition                 1 year 127 days        
Share-based Payment Arrangement, Nonvested Award, Cost Not yet Recognized, Amount, Total | $                 $ 1.30        
Subsequent Event [Member]                          
Share-based Compensation Arrangement by Share-based Payment Award, Options, Grants in Period, Gross 40,000                        
The 2018 Equity Incentive Plan [Member]                          
Share-based Compensation Arrangement by Share-based Payment Award, Number of Shares Available for Grant               4,160,000          
Share Based Compensation Arrangement By Share Based Payment Award, Percentage Applied on Outstanding Shares of Common Stock For Automatically Increase on Each Year               5.00%          
Share-based Compensation Arrangement by Share-based Payment Award, Number of Additional Shares Authorized       761,957                  
The 2018 Equity Incentive Plan [Member] | Subsequent Event [Member]                          
Share-based Compensation Arrangement by Share-based Payment Award, Number of Additional Shares Authorized   963,192                      
The 2009 Plan [Member]                          
Common Stock, Capital Shares Reserved for Future Issuance               554,963          
The 2018 Employee Stock Purchase Plan [Member]                          
Share Based Compensation Arrangement By Share Based Payment Award, Percentage Applied on Outstanding Shares of Common Stock For Automatically Increase on Each Year               2.00%          
Share-based Compensation Arrangement by Share-based Payment Award, Number of Shares Authorized               208,500          
Conversion of Preferred Stock to Common Stock [Member]                          
Conversion of Stock, Shares Converted                   1,394,953      
Conversion of Stock, Shares Issued               1,235,219   9,324,177      
World Wide Holdings, LLC [Member]                          
Class of Warrant or Right, Number of Securities Called by Warrants or Rights         50,000                
Class of Warrant or Right, Exercised During Period         34,615                
Class of Warrant or Right, Cancelled During Period         15,385                
Warrants Issued with Registered Direct Offering [Member]                          
Class of Warrant or Right, Number of Securities Called by Warrants or Rights     3,167,986                    
Class of Warrant or Right, Exercise Price of Warrants or Rights | $ / shares     $ 0.46                    
Warrants Issued to Underwriter [Member]                          
Class of Warrant or Right, Number of Securities Called by Warrants or Rights     443,518           3,167,986        
Class of Warrant or Right, Exercise Price of Warrants or Rights | $ / shares     $ 0.58           $ 0.46        
Warrants, Exercise Price, Percentage of RDO Price Per Share | $ / shares     $ 125                    
Class of Warrant or Right, Issued in Period                   38,400      
Class of Warrant or Right, Issued During Period, Exercise Price | $ / shares                   $ 6.25      
Warrants Issued to Investors to Purchase Common Stock [Member]                          
Class of Warrant or Right, Issued in Period                   2,283,740      
Class of Warrant or Right, Issued During Period, Exercise Price | $ / shares                   $ 4.25      
Warrants Issued for Services [Member]                          
Class of Warrant or Right, Issued in Period                   844,352      
Warrants and Rights Outstanding | $                   $ 2,203,506      
Warrants Issued for Services [Member] | Cancer Revolution, LLC [Member]                          
Class of Warrant or Right, Issued in Period                   425,000      
Warrants Issued for Services [Member] | Cancer Biotech, LLC [Member]                          
Class of Warrant or Right, Issued in Period                   225,000      
Warrants Issued for Services [Member] | Inception Capital Management, LLC [Member]                          
Class of Warrant or Right, Issued in Period                   144,352      
Warrants Issued for Services [Member] | World Wide Holdings, LLC [Member]                          
Class of Warrant or Right, Issued in Period                   50,000      
Class of Warrant or Right, Issued During Period, Exercise Price | $ / shares                   $ 5      
Warrants Issued for Services [Member] | FundAthena, Inc [Member]                          
Class of Warrant or Right, Number of Securities Called by Warrants or Rights                       6,000  
Class of Warrant or Right, Exercise Price of Warrants or Rights | $ / shares                       $ 5  
Class of Warrant or Right, Issued in Period                   0      
Accounts Payable, Total | $                       $ 30,000  
Maximum [Member]                          
Share-based Compensation Arrangement by Share-based Payment Award, Award Vesting Period                 4 years        
Share-based Compensation Arrangement by Share-based Payment Award, Options, Outstanding, Weighted Average Exercise Price, Ending Balance | $ / shares                 $ 9.80 $ 9.80      
Share-based Compensation Arrangement by Share-based Payment Award, Options, Vested, Weighted Average Grant Date Fair Value | $ / shares                 7.93        
Share-based Compensation Arrangements by Share-based Payment Award, Options, Grants in Period, Weighted Average Exercise Price | $ / shares                 $ 1.62        
Minimum [Member]                          
Share-based Compensation Arrangement by Share-based Payment Award, Award Vesting Period                 1 year        
Share-based Compensation Arrangement by Share-based Payment Award, Options, Outstanding, Weighted Average Exercise Price, Ending Balance | $ / shares                 $ 0.001 $ 2.15      
Share-based Compensation Arrangement by Share-based Payment Award, Options, Vested, Weighted Average Grant Date Fair Value | $ / shares                 0.001        
Share-based Compensation Arrangements by Share-based Payment Award, Options, Grants in Period, Weighted Average Exercise Price | $ / shares                 $ 0.30        
Weighted Average [Member] | Share-based Payment Arrangement, Option [Member] | Graded Vesting Method [Member]                          
Share-based Payment Arrangement, Nonvested Award, Cost Not yet Recognized, Period for Recognition                 1 year 313 days        
Weighted Average [Member] | Share-based Payment Arrangement, Option [Member] | Cliff Vesting Method [Member]                          
Share-based Payment Arrangement, Nonvested Award, Cost Not yet Recognized, Period for Recognition                 171 days        
IPO [Member]                          
Stock Issued During Period, Shares, New Issues               1,280,000          
Sale of Stock, Price Per Share | $ / shares               $ 5          
Proceeds from Issuance Initial Public Offering | $               $ 5,025,000          
Payments of Stock Issuance Costs | $               $ 895,000          
Percentage of Common Stock Issuance of Warrant or Right Issued               3.00%          
Class of Warrant or Right, Number of Securities Called by Warrants or Rights               38,400          
Private Placement [Member]                          
Stock Issued During Period, Shares, New Issues             828,500   350,000        
Sale of Stock, Price Per Share | $ / shares             $ 12.07            
Class of Warrant or Right, Exercise Price of Warrants or Rights | $ / shares             $ 15.62            
Proceeds from Issuance of Common Stock | $             $ 9,250,000            
Private Placement [Member] | Securities Purchase Agreement [Member]                          
Stock Issued During Period, Shares, New Issues           1,174,440              
Class of Warrant or Right, Number of Securities Called by Warrants or Rights           2,283,740     2,283,740        
Class of Warrant or Right, Exercise Price of Warrants or Rights | $ / shares           $ 4.25     $ 0.46        
Private Placement [Member] | Maximum [Member]                          
Class of Warrant or Right, Number of Securities Called by Each Warrant or Right             621,376            
Private Placement [Member] | Minimum [Member]                          
Class of Warrant or Right, Exercise Price of Warrants or Rights | $ / shares             $ 4.25            
Registered Direct Offering [Member]                          
Stock Issued During Period, Shares, New Issues     3,167,986           3,167,986        
Proceeds from Issuance of Common Stock | $     $ 1,093,000           $ 1,267,194        
Shares Issued, Price Per Share | $ / shares     $ 0.40                    
Registered Direct Offering [Member] | Underwriter [Member]                          
Stock Issued During Period, Shares, New Issues                 443,518        
Percentage of Common Stock Issuance of Warrant or Right Issued     7.00%                    
Shares Issued, Price Per Share | $ / shares                 $ 0.58        
IPO and Private Placement [Member]                          
Stock Issued During Period, Shares, New Issues                   3,282,940      
Proceeds from Issuance of Common Stock | $                   $ 16,400,000