0001185185-17-002555.txt : 20171205 0001185185-17-002555.hdr.sgml : 20171205 20171205165336 ACCESSION NUMBER: 0001185185-17-002555 CONFORMED SUBMISSION TYPE: 10-Q/A PUBLIC DOCUMENT COUNT: 37 CONFORMED PERIOD OF REPORT: 20170930 FILED AS OF DATE: 20171205 DATE AS OF CHANGE: 20171205 FILER: COMPANY DATA: COMPANY CONFORMED NAME: Genprex, Inc. CENTRAL INDEX KEY: 0001595248 STANDARD INDUSTRIAL CLASSIFICATION: PHARMACEUTICAL PREPARATIONS [2834] IRS NUMBER: 900772347 FISCAL YEAR END: 1213 FILING VALUES: FORM TYPE: 10-Q/A SEC ACT: 1934 Act SEC FILE NUMBER: 001-38244 FILM NUMBER: 171240306 BUSINESS ADDRESS: STREET 1: 100 CONGRESS AVENUE STREET 2: SUITE 2000 CITY: AUSTIN STATE: TX ZIP: 78701 BUSINESS PHONE: 512-708-0155 MAIL ADDRESS: STREET 1: 100 CONGRESS AVENUE STREET 2: SUITE 2000 CITY: AUSTIN STATE: TX ZIP: 78701 10-Q/A 1 genprex10qa093017.htm 10-Q/A


UNITED STATES
SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549  
 


FORM 10-Q/A
 

 
(Mark One)
 
 
QUARTERLY REPORT UNDER SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934
 
 
For the quarterly period ended September 30, 2017
 
 
r
TRANSITION REPORT UNDER SECTION 13 OR 15(d) OF THE EXCHANGE ACT
 
 
For the transition period from __________________ to ______________
 
Commission file number: 001-38244

GENPREX, INC.
(Exact name of registrant as specified in its charter)
 
Delaware
90 - 0772347
(State or other jurisdiction of
incorporation or organization)
(I.R.S. Employer
Identification Number)
 
 
100 Congress Avenue, Suite 2000, Austin, TX
78701
(Address of principal executive offices)
(Zip Code)
 
Registrant’s telephone number, including area code: (512) 370-4081
 
 
Indicate by check mark whether the registrant (1) has filed all reports required to be filed by Section 13 or 15(d) of the Securities Exchange Act of 1934 during the preceding 12 months (or for such shorter period that the registrant was required to file such reports), and (2) has been subject to such filing requirements for the past 90 days.  Yes ☐   No ☒

Indicate by check mark whether the registrant has submitted electronically and posted on its corporate Web site, if any, every Interactive Data File required to be submitted and posted pursuant to Rule 405 of Regulation S-T during the preceding 12 months (or for such shorter period that the registrant was required to submit and post such files). Yes ☐  No ☒
 
Indicate by check mark whether the registrant is a large accelerated filer, an accelerated filer, a non-accelerated filer, smaller reporting company, or an emerging growth company. See definition of “large accelerated filer,” accelerated filer” “smaller reporting company,” and “emerging growth company” in Rule 12b-2 of the Exchange Act: 

Large accelerated filer ☐
 
Accelerated filer ☐
 
 
 
Non-accelerated filer ☐  (Do not check if a smaller reporting company)
 
Smaller Reporting Company 
 
 
 
Emerging growth company  ☒
 
 
 
If an emerging growth company, indicate by check mark if the registrant has elected not to use the extended transition period for complying with any new or revised financial accounting standards provided pursuant to Section 13(a) of the Exchange Act. ☒
 
Indicate by check mark whether the registrant is a shell company (as defined in Rule 12b-2 of the Exchange Act). Yes ☐  No     
 
As of November 27, 2017, the registrant had 333,065 shares of voting common stock, par value $0.001 per share, outstanding and 25,611 shares of non-voting common stock, par value $0.001 per share, outstanding.
 

EXPLANATORY NOTE

The sole purpose of this Amendment No. 1 to the Quarterly Report on Form 10-Q for the quarterly period ended September 30, 2017 of Genprex, Inc. (the “Company”) filed with the Securities and Exchange Commission on November 27, 2017 (the “Form 10-Q”) is to include Exhibit 101 to the Form 10-Q, which contains the XBRL (eXtensible Business Reporting Language) Interactive Data File for the financial statements and notes.

No other changes have been made to the Form 10-Q. This Amendment No. 1 to the Form 10-Q speaks as of the original filing date of the Form 10-Q, does not reflect events that may have occurred subsequent to the original filing date, and does not modify or update in any way disclosures made in the original Form 10-Q.
 
 


ITEM 6. EXHIBITS
 
Exhibit
Number
 
Description of Exhibit
 
 
 
 
 
 
 
1.1(1)
 
 
 
4.7(1)
 
 
 
31.1(2)
 
 
 
31.2(2)
 
 
 
32.1(2)
 
 
 
101.INS
 
XBRL Instance Document
 
 
101.SCH
 
XBRL Taxonomy Extension Schema Document
 
 
101.CAL
 
XBRL Taxonomy Extension Calculation Linkbase Document
 
 
101.DEF
 
XBRL Taxonomy Extension Definition Linkbase Document
 
 
101.LAB
 
XBRL Taxonomy Extension Label Linkbase Document
 
 
101.PRE
 
XBRL Taxonomy Extension Presentation Linkbase Document
   
 
(1)
Incorporated by reference to Amendment no. 6 to the Registrant’s Registration Statement on Form S-1 (File No. 333-219386), filed with the Securities and Exchange Commission on October 10, 2017.
(2)
These exhibits were previously included in the Company’s Quarterly Report on Form 10-Q for the quarterly period ended September 30, 2017, filed with the Securities and Exchange Commission on November 27, 2017.
 

 


SIGNATURES

Pursuant to the requirements of the Securities Exchange Act of 1934, as amended, the Registrant has duly caused this report to be signed on its behalf by the undersigned thereunto duly authorized.
 
 
GENPREX, INC.
 
 
 
 
 
Date: December 5, 2017
By:
/s/ Rodney Varner
 
 
 
Rodney Varner
 
 
 
Chief Executive Officer
(Principal Executive Officer)
 
 
 
 
 
 
 
 
 
 
By:
/s/ Ryan Confer
 
 
 
Ryan Confer
 
 
 
Chief Financial Officer
(Principal Financial Officer)
 
 
 
 
 

 
 
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(&#x201c;we&#x201d; or &#x201c;the Company&#x201d;), is a privately held, clinical-stage biopharmaceutical company developing immunogene therapies for cancer. Our first product candidate, branded as Oncoprex&#x2122;, is in phase II clinical trials for lung cancer patients in the United States.</div><br/><div style="TEXT-ALIGN: left; FONT-FAMILY: 'Times New Roman', Times, serif; FONT-SIZE: 10pt">We are subject to all the risks inherent in a start-up company in the biopharmaceutical industry. The biopharmaceutical industry is subject to rapid and technological change. We have numerous competitors, including major pharmaceutical and chemical companies, specialized biotechnology firms, universities and other research institutions. These competitors may succeed in developing technologies and products that are more effective than any that are being developed by us or that would render our technology and products obsolete and noncompetitive. Many of these competitors have substantially greater financial and technical resources than us. In addition, many of our competitors have significantly greater experience than us in pre-clinical testing and human clinical trials of new or improved pharmaceutical products and in obtaining FDA and other regulatory approvals on products for use in health care.</div><br/><div style="TEXT-ALIGN: left; FONT-STYLE: italic; FONT-FAMILY: 'Times New Roman', Times, serif; FONT-SIZE: 10pt"><font style="text-decoration:underline">Initial Public Offering</font></div><br/><div style="TEXT-ALIGN: left; FONT-FAMILY: 'Times New Roman', Times, serif; FONT-SIZE: 10pt">On July 21, 2017, we filed a registration statement on Form S-1 (File No. 333-219386) relating to the initial public offering (IPO) of our common stock.&#160; The Registration Statement, as amended, was declared effective by the Securities and Exchange Commission (SEC) on October 13, 2017.&#160; On November 14, 2017, we filed our updated final prospectus with the SEC, relating to the sale of up to 4,500,000 shares of our common stock at a price of $5.00 per share.&#160; The IPO is ongoing.</div><br/><div style="TEXT-ALIGN: left; FONT-FAMILY: 'Times New Roman', Times, serif; FONT-SIZE: 10pt">In connection with the completion of the IPO, all of our outstanding shares of convertible preferred stock will be converted into an aggregate of 1,394,953 shares of voting common stock (before giving effect to the forward split described below), all of our outstanding shares of non-voting common stock will be converted into an aggregate of 25,611 shares of voting common stock (before giving effect to the forward split described below), and each of our outstanding shares of voting common stock will be split and converted into 6.6841954 shares of voting common stock.&#160; The accompanying financial statements and note to the financial statements do not give effect to these changes.</div><br/><div style="TEXT-ALIGN: left; FONT-STYLE: italic; FONT-FAMILY: 'Times New Roman', Times, serif; FONT-SIZE: 10pt"><font style="text-decoration:underline">Capital Requirements, Liquidity and Going Concern Considerations</font></div><br/><div style="TEXT-ALIGN: left; FONT-FAMILY: 'Times New Roman', Times, serif; FONT-SIZE: 10pt">Our financial statements are prepared using the generally accepted accounting principles applicable to a going concern, which contemplates the realization of assets and liquidation of liabilities in the normal course of business. However, as shown in the accompanying financial statements, we have sustained substantial losses from operations since inception and have no current source of revenue. In addition, we have used, rather than provided, cash in our operations. We expect to continue to incur significant expenditures to further clinical trials for the commercial development of our patents.</div><br/><div style="TEXT-ALIGN: left; FONT-FAMILY: 'Times New Roman', Times, serif; FONT-SIZE: 10pt">Management recognizes that we must obtain additional resources to successfully commercialize our intellectual property. To date, we have received funding in the form of equity and debt, and plan to either continue obtaining funding through 2017 or until we have secured a capital market transaction. However, no assurances can be given that we will be successful in raising additional capital. If we are not able to timely and successfully raise additional capital, the timing of our clinical trials, financial condition and results of operations will continue to be materially affected. These financial statements do not include any adjustments relating to the recoverability and classification of recorded asset amounts and classification of liabilities that might be necessary should we be unable to continue as a going concern.</div><br/></div> 4500000 5.00 1394953 25611 6.6841954 <div style="font-family: 'Times New Roman', Times, serif; font-size: 10pt; "> <div style="TEXT-ALIGN: left; FONT-FAMILY: 'Times New Roman', Times, serif; FONT-SIZE: 10pt"><font style="text-decoration:underline">Note 2&#x2014;Summary of Significant Accounting Policies</font></div><br/><div style="TEXT-ALIGN: left; FONT-FAMILY: 'Times New Roman', Times, serif; FONT-SIZE: 10pt">The financial statements have been prepared in accordance with U.S. generally accepted accounting principles (&#x201c;U.S. GAAP&#x201d;) and reflect all adjustments, which are of a normal and recurring nature, that are, in the opinion of management, necessary for a fair presentation of our financial position and results of operations for the related periods. The results of operations for any interim periods are not necessarily indicative of results to be expected for the full year. A summary of our significant accounting policies consistently applied in the preparation of the accompanying financial statements follows.</div><br/><div style="TEXT-ALIGN: left; FONT-STYLE: italic; FONT-FAMILY: 'Times New Roman', Times, serif; FONT-SIZE: 10pt"><font style="text-decoration:underline">Restatement of Balance Sheet at December 31, 2016</font></div><br/><div style="TEXT-ALIGN: left; FONT-FAMILY: 'Times New Roman', Times, serif; FONT-SIZE: 10pt">Subsequent to the auditors&#x2019; issuance of their report on our December 31, 2016 financial statements, management became aware of a scrivener&#x2019;s error in the terms of certain options granted, resulting in a $136,810 increase in share based compensation (accumulated deficit) and additional paid-in capital during the fourth quarter of 2016.</div><br/><div style="TEXT-ALIGN: left; FONT-STYLE: italic; FONT-FAMILY: 'Times New Roman', Times, serif; FONT-SIZE: 10pt"><font style="text-decoration:underline">Use of Estimates</font></div><br/><div style="TEXT-ALIGN: left; FONT-FAMILY: 'Times New Roman', Times, serif; FONT-SIZE: 10pt">The preparation of our financial statements in conformity with GAAP requires us to make estimates and assumptions that affect the reported amounts of assets and liabilities and disclosure of contingent assets and liabilities at the date of the financial statements and the reported amounts of expenses during the reporting period. Actual results could differ from those estimates.</div><br/><div style="TEXT-ALIGN: left; FONT-STYLE: italic; FONT-FAMILY: 'Times New Roman', Times, serif; FONT-SIZE: 10pt"><font style="text-decoration:underline">Cash and Cash Equivalents</font></div><br/><div style="TEXT-ALIGN: left; FONT-FAMILY: 'Times New Roman', Times, serif; FONT-SIZE: 10pt">We consider all highly liquid short-term investments with an initial maturity of three months or less to be cash equivalents. Any amounts of cash in financial institutions which exceed FDIC insured limits expose us to cash concentration risk. We have no cash equivalents, and had $118,950 and $1,351,868 in excess of FDIC insured limits of $250,000 at September 30, 2017 and December 31, 2016, respectively.</div><br/><div style="TEXT-ALIGN: left; FONT-STYLE: italic; FONT-FAMILY: 'Times New Roman', Times, serif; FONT-SIZE: 10pt"><font style="text-decoration:underline">Fair Value of Financial Instruments</font></div><br/><div style="TEXT-ALIGN: left; FONT-FAMILY: 'Times New Roman', Times, serif; FONT-SIZE: 10pt">The carrying amounts reported in the balance sheet for cash, accounts payable and accrued expenses approximate fair value because of the immediate or short-term maturity of these financial instruments.</div><br/><div style="TEXT-ALIGN: left; FONT-FAMILY: 'Times New Roman', Times, serif; FONT-SIZE: 10pt">ASC 820 defines fair value, provides a consistent framework for measuring fair value under GAAP and expands fair value financial statement disclosure requirements. ASC 820&#x2019;s valuation techniques are based on observable and unobservable inputs. Observable inputs reflect readily obtainable data from independent sources, while unobservable inputs reflect our market assumptions. ASC 820 classifies these inputs into the following hierarchy:</div><br/><div style="TEXT-ALIGN: left; FONT-FAMILY: 'Times New Roman', Times, serif; MARGIN-LEFT: 36pt; FONT-SIZE: 10pt">Level 1:<font style="FONT-FAMILY: 'Times New Roman', serif; FONT-SIZE: 1pt">&#160;</font>Quoted prices for identical instruments in active markets</div><br/><div style="TEXT-ALIGN: left; FONT-FAMILY: 'Times New Roman', Times, serif; MARGIN-LEFT: 36pt; FONT-SIZE: 10pt">Level 2: Quoted prices for similar instruments in active markets; quoted prices for identical or similar instruments in markets that are not active; and model-derived valuations whose inputs are observable or whose significant value drivers are observable</div><br/><div style="TEXT-ALIGN: left; FONT-FAMILY: 'Times New Roman', Times, serif; MARGIN-LEFT: 36pt; FONT-SIZE: 10pt">Level 3:<font style="FONT-FAMILY: 'Times New Roman', serif; FONT-SIZE: 1pt">&#160;</font>Instruments with primarily unobservable value drivers.</div><br/><div style="TEXT-ALIGN: left; FONT-STYLE: italic; FONT-FAMILY: 'Times New Roman', Times, serif; FONT-SIZE: 10pt"><font style="text-decoration:underline">Property and Equipment</font></div><br/><div style="TEXT-ALIGN: left; FONT-FAMILY: 'Times New Roman', Times, serif; FONT-SIZE: 10pt">Furniture and equipment are stated at cost. Depreciation is calculated using the straight line method over the estimated useful lives of the assets, which range from three to five years. Routine maintenance and repairs are charged to expense as incurred and major renovations or improvements are capitalized.</div><br/><div style="TEXT-ALIGN: left; FONT-STYLE: italic; FONT-FAMILY: 'Times New Roman', Times, serif; FONT-SIZE: 10pt"><font style="text-decoration:underline">Research and Development Materials Costs</font></div><br/><div style="TEXT-ALIGN: left; FONT-FAMILY: 'Times New Roman', Times, serif; FONT-SIZE: 10pt">Research and development expenditures are comprised of costs incurred to conduct research and development activities. These include payments to collaborative research partners, including wages and associated employee benefits, facilities and overhead costs. These expenditures relate to Phase 1 and 2 clinical trials and are expensed as incurred. Purchased materials to be used in future research are capitalized and included in prepaid expenses.</div><br/><div style="TEXT-ALIGN: left; FONT-STYLE: italic; FONT-FAMILY: 'Times New Roman', Times, serif; FONT-SIZE: 10pt"><font style="text-decoration:underline">Awards</font></div><br/><div style="TEXT-ALIGN: left; FONT-FAMILY: 'Times New Roman', Times, serif; FONT-SIZE: 10pt">In 2010, we were awarded $4.5 million from the State of Texas Emerging Technology Fund (&#x201c;TETF&#x201d;). The award was received in two tranches of $2.25 million during 2010 and 2011. The award proceeds were used for the development and future commercialization of our nanomolecular therapy product for the treatment of cancer. In consideration for the award, we provided the TETF with an &#x201c;Investment Unit&#x201d;, consisting of (i) a Promissory Note (&#x201c;Note&#x201d;) and (ii) a right to purchase our equity shares (&#x201c;Warrant&#x201d;). The funds received for this award were assigned to the Investment Unit, and classified separately from equity as &#x201c;mezzanine&#x201d; in the balance sheet.</div><br/><div style="TEXT-ALIGN: left; FONT-FAMILY: 'Times New Roman', Times, serif; FONT-SIZE: 10pt">In 2010, we also were awarded approximately $244,500 from the U.S. Treasury Department for our QTDP Program Nanoparticle Therapy for Lung Cancer. The award was received during 2011 for our historical activities, and required no prospective expenditures. We accounted for these funds received as revenue at that time.</div><br/><div style="TEXT-ALIGN: left; FONT-STYLE: italic; FONT-FAMILY: 'Times New Roman', Times, serif; FONT-SIZE: 10pt"><font style="text-decoration:underline">Intellectual Property</font></div><br/><div style="TEXT-ALIGN: left; FONT-FAMILY: 'Times New Roman', Times, serif; FONT-SIZE: 10pt">Intellectual property consists of external legal and related costs associated with patents and other proprietary technology acquired, licensed, or maintained by us that we believe contribute to a probable economic benefit toward such patents and activities. These legal costs incurred in connection with the patent applications and patent maintenance are capitalized. Intellectual property is stated at cost, to be amortized on a straight-line basis over the estimated useful lives of the assets.</div><br/><div style="TEXT-ALIGN: left; FONT-STYLE: italic; FONT-FAMILY: 'Times New Roman', Times, serif; FONT-SIZE: 10pt"><font style="text-decoration:underline">Accounting for Stock-Based Compensation</font></div><br/><div style="TEXT-ALIGN: left; FONT-FAMILY: 'Times New Roman', Times, serif; FONT-SIZE: 10pt">We use the fair value-based method of accounting for stock-based compensation for options granted to employees, independent consultants and contractors. We measure options granted at fair value determined as of the grant date, and recognize the expense over the periods in which the related services are rendered based on the terms and conditions of the award. Generally, where the award only has a service condition, the requisite service period is the same as the vesting period.</div><br/><div style="TEXT-ALIGN: left; FONT-STYLE: italic; FONT-FAMILY: 'Times New Roman', Times, serif; FONT-SIZE: 10pt"><font style="text-decoration:underline">Financial Instruments</font></div><br/><div style="TEXT-ALIGN: left; FONT-FAMILY: 'Times New Roman', Times, serif; FONT-SIZE: 10pt">We have elected the Fair Value Option to account for the Investment Unit at fair value as a combined hybrid financial instrument containing a Warrant and a Note (see Note 4). Prior to its exercise, the Warrant component was not classified within equity, as the exercise price of the warrants was affected by the market price of our stock in a future qualifying financing transaction and was not considered to be indexed to our own stock. The Note is not classified within liabilities, as our management can determine the timing of the repayment obligation, if any. As a result, the Warrant and Note that comprised the Investment Unit were aggregated and classified within the mezzanine section of the balance sheet.</div><br/><div style="TEXT-ALIGN: left; FONT-FAMILY: 'Times New Roman', Times, serif; FONT-SIZE: 10pt">Due to the contingent terms of the financial instruments, changes in the fair value of the Investment Unit were calculated and realized in earnings. There were no changes in the fair value of the Investment Unit at September 30, 2017.</div><br/><div style="TEXT-ALIGN: left; FONT-STYLE: italic; FONT-FAMILY: 'Times New Roman', Times, serif; FONT-SIZE: 10pt"><font style="text-decoration:underline">Long-Lived Assets</font></div><br/><div style="TEXT-ALIGN: left; FONT-FAMILY: 'Times New Roman', Times, serif; FONT-SIZE: 10pt">We review long-lived assets and certain identifiable intangibles held and used for possible impairment whenever events or changes in circumstances indicate that the carrying amount of an asset may not be recoverable. In evaluating the fair value and future benefits of its intangible assets, management performs an analysis of the anticipated undiscounted future net cash flow of the individual assets over the remaining amortization period. We recognize an impairment loss if the carrying value of the asset exceeds the expected future cash flows. During the nine months ended September 30, 2017 and the year ended December 31, 2016, there were no deemed impairments of our long-lived assets.</div><br/><div style="TEXT-ALIGN: left; FONT-STYLE: italic; FONT-FAMILY: 'Times New Roman', Times, serif; FONT-SIZE: 10pt"><font style="text-decoration:underline">Recent Accounting Developments</font></div><br/><div style="TEXT-ALIGN: left; FONT-FAMILY: 'Times New Roman', Times, serif; FONT-SIZE: 10pt">Accounting pronouncements issued but not effective until after September 30, 2017 are not expected to have a significant effect on our financial condition, results of operations, or cash flows.</div><br/></div> 136810 <div style="font-family: 'Times New Roman', Times, serif; font-size: 10pt; "> <div style="TEXT-ALIGN: left; FONT-STYLE: italic; FONT-FAMILY: 'Times New Roman', Times, serif; FONT-SIZE: 10pt"><font style="text-decoration:underline">Use of Estimates</font></div><br/><div style="TEXT-ALIGN: left; FONT-FAMILY: 'Times New Roman', Times, serif; FONT-SIZE: 10pt">The preparation of our financial statements in conformity with GAAP requires us to make estimates and assumptions that affect the reported amounts of assets and liabilities and disclosure of contingent assets and liabilities at the date of the financial statements and the reported amounts of expenses during the reporting period. Actual results could differ from those estimates.</div></div> <div style="font-family: 'Times New Roman', Times, serif; font-size: 10pt; "> <div style="TEXT-ALIGN: left; FONT-STYLE: italic; FONT-FAMILY: 'Times New Roman', Times, serif; FONT-SIZE: 10pt"><font style="text-decoration:underline">Cash and Cash Equivalents</font></div><br/><div style="TEXT-ALIGN: left; FONT-FAMILY: 'Times New Roman', Times, serif; FONT-SIZE: 10pt">We consider all highly liquid short-term investments with an initial maturity of three months or less to be cash equivalents. Any amounts of cash in financial institutions which exceed FDIC insured limits expose us to cash concentration risk. We have no cash equivalents, and had $118,950 and $1,351,868 in excess of FDIC insured limits of $250,000 at September 30, 2017 and December 31, 2016, respectively.</div></div> 118950 1351868 250000 <div style="font-family: 'Times New Roman', Times, serif; font-size: 10pt; "> <div style="TEXT-ALIGN: left; FONT-STYLE: italic; FONT-FAMILY: 'Times New Roman', Times, serif; FONT-SIZE: 10pt"><font style="text-decoration:underline">Fair Value of Financial Instruments</font></div><br/><div style="TEXT-ALIGN: left; FONT-FAMILY: 'Times New Roman', Times, serif; FONT-SIZE: 10pt">The carrying amounts reported in the balance sheet for cash, accounts payable and accrued expenses approximate fair value because of the immediate or short-term maturity of these financial instruments.</div><br/><div style="TEXT-ALIGN: left; FONT-FAMILY: 'Times New Roman', Times, serif; FONT-SIZE: 10pt">ASC 820 defines fair value, provides a consistent framework for measuring fair value under GAAP and expands fair value financial statement disclosure requirements. ASC 820&#x2019;s valuation techniques are based on observable and unobservable inputs. Observable inputs reflect readily obtainable data from independent sources, while unobservable inputs reflect our market assumptions. ASC 820 classifies these inputs into the following hierarchy:</div><br/><div style="TEXT-ALIGN: left; FONT-FAMILY: 'Times New Roman', Times, serif; MARGIN-LEFT: 36pt; FONT-SIZE: 10pt">Level 1:<font style="FONT-FAMILY: 'Times New Roman', serif; FONT-SIZE: 1pt">&#160;</font>Quoted prices for identical instruments in active markets</div><br/><div style="TEXT-ALIGN: left; FONT-FAMILY: 'Times New Roman', Times, serif; MARGIN-LEFT: 36pt; FONT-SIZE: 10pt">Level 2: Quoted prices for similar instruments in active markets; quoted prices for identical or similar instruments in markets that are not active; and model-derived valuations whose inputs are observable or whose significant value drivers are observable</div><br/><div style="TEXT-ALIGN: left; FONT-FAMILY: 'Times New Roman', Times, serif; MARGIN-LEFT: 36pt; FONT-SIZE: 10pt">Level 3:<font style="FONT-FAMILY: 'Times New Roman', serif; FONT-SIZE: 1pt">&#160;</font>Instruments with primarily unobservable value drivers.</div></div> <div style="font-family: 'Times New Roman', Times, serif; font-size: 10pt; "> <div style="TEXT-ALIGN: left; FONT-STYLE: italic; FONT-FAMILY: 'Times New Roman', Times, serif; FONT-SIZE: 10pt"><font style="text-decoration:underline">Property and Equipment</font></div><br/><div style="TEXT-ALIGN: left; FONT-FAMILY: 'Times New Roman', Times, serif; FONT-SIZE: 10pt">Furniture and equipment are stated at cost. Depreciation is calculated using the straight line method over the estimated useful lives of the assets, which range from three to five years. Routine maintenance and repairs are charged to expense as incurred and major renovations or improvements are capitalized.</div></div> P3Y P5Y <div style="font-family: 'Times New Roman', Times, serif; font-size: 10pt; "> <div style="TEXT-ALIGN: left; FONT-STYLE: italic; FONT-FAMILY: 'Times New Roman', Times, serif; FONT-SIZE: 10pt"><font style="text-decoration:underline">Research and Development Materials Costs</font></div><br/><div style="TEXT-ALIGN: left; FONT-FAMILY: 'Times New Roman', Times, serif; FONT-SIZE: 10pt">Research and development expenditures are comprised of costs incurred to conduct research and development activities. These include payments to collaborative research partners, including wages and associated employee benefits, facilities and overhead costs. These expenditures relate to Phase 1 and 2 clinical trials and are expensed as incurred. Purchased materials to be used in future research are capitalized and included in prepaid expenses.</div></div> <div style="font-family: 'Times New Roman', Times, serif; font-size: 10pt; "> <div style="TEXT-ALIGN: left; FONT-STYLE: italic; FONT-FAMILY: 'Times New Roman', Times, serif; FONT-SIZE: 10pt"><font style="text-decoration:underline">Awards</font></div><br/><div style="TEXT-ALIGN: left; FONT-FAMILY: 'Times New Roman', Times, serif; FONT-SIZE: 10pt">In 2010, we were awarded $4.5 million from the State of Texas Emerging Technology Fund (&#x201c;TETF&#x201d;). The award was received in two tranches of $2.25 million during 2010 and 2011. The award proceeds were used for the development and future commercialization of our nanomolecular therapy product for the treatment of cancer. In consideration for the award, we provided the TETF with an &#x201c;Investment Unit&#x201d;, consisting of (i) a Promissory Note (&#x201c;Note&#x201d;) and (ii) a right to purchase our equity shares (&#x201c;Warrant&#x201d;). The funds received for this award were assigned to the Investment Unit, and classified separately from equity as &#x201c;mezzanine&#x201d; in the balance sheet.</div><br/><div style="TEXT-ALIGN: left; FONT-FAMILY: 'Times New Roman', Times, serif; FONT-SIZE: 10pt">In 2010, we also were awarded approximately $244,500 from the U.S. Treasury Department for our QTDP Program Nanoparticle Therapy for Lung Cancer. The award was received during 2011 for our historical activities, and required no prospective expenditures. We accounted for these funds received as revenue at that time.</div></div> 4500000 2 2250000 2250000 244500 <div style="font-family: 'Times New Roman', Times, serif; font-size: 10pt; "> <div style="TEXT-ALIGN: left; FONT-STYLE: italic; FONT-FAMILY: 'Times New Roman', Times, serif; FONT-SIZE: 10pt"><font style="text-decoration:underline">Intellectual Property</font></div><br/><div style="TEXT-ALIGN: left; FONT-FAMILY: 'Times New Roman', Times, serif; FONT-SIZE: 10pt">Intellectual property consists of external legal and related costs associated with patents and other proprietary technology acquired, licensed, or maintained by us that we believe contribute to a probable economic benefit toward such patents and activities. These legal costs incurred in connection with the patent applications and patent maintenance are capitalized. Intellectual property is stated at cost, to be amortized on a straight-line basis over the estimated useful lives of the assets.</div></div> <div style="font-family: 'Times New Roman', Times, serif; font-size: 10pt; "> <div style="TEXT-ALIGN: left; FONT-STYLE: italic; FONT-FAMILY: 'Times New Roman', Times, serif; FONT-SIZE: 10pt"><font style="text-decoration:underline">Accounting for Stock-Based Compensation</font></div><br/><div style="TEXT-ALIGN: left; FONT-FAMILY: 'Times New Roman', Times, serif; FONT-SIZE: 10pt">We use the fair value-based method of accounting for stock-based compensation for options granted to employees, independent consultants and contractors. We measure options granted at fair value determined as of the grant date, and recognize the expense over the periods in which the related services are rendered based on the terms and conditions of the award. Generally, where the award only has a service condition, the requisite service period is the same as the vesting period.</div></div> <div style="font-family: 'Times New Roman', Times, serif; font-size: 10pt; "> <div style="TEXT-ALIGN: left; FONT-STYLE: italic; FONT-FAMILY: 'Times New Roman', Times, serif; FONT-SIZE: 10pt"><font style="text-decoration:underline">Financial Instruments</font></div><br/><div style="TEXT-ALIGN: left; FONT-FAMILY: 'Times New Roman', Times, serif; FONT-SIZE: 10pt">We have elected the Fair Value Option to account for the Investment Unit at fair value as a combined hybrid financial instrument containing a Warrant and a Note (see Note 4). Prior to its exercise, the Warrant component was not classified within equity, as the exercise price of the warrants was affected by the market price of our stock in a future qualifying financing transaction and was not considered to be indexed to our own stock. The Note is not classified within liabilities, as our management can determine the timing of the repayment obligation, if any. As a result, the Warrant and Note that comprised the Investment Unit were aggregated and classified within the mezzanine section of the balance sheet.</div><br/><div style="TEXT-ALIGN: left; FONT-FAMILY: 'Times New Roman', Times, serif; FONT-SIZE: 10pt">Due to the contingent terms of the financial instruments, changes in the fair value of the Investment Unit were calculated and realized in earnings. There were no changes in the fair value of the Investment Unit at September 30, 2017.</div></div> <div style="font-family: 'Times New Roman', Times, serif; font-size: 10pt; "> <div style="TEXT-ALIGN: left; FONT-STYLE: italic; FONT-FAMILY: 'Times New Roman', Times, serif; FONT-SIZE: 10pt"><font style="text-decoration:underline">Long-Lived Assets</font></div><br/><div style="TEXT-ALIGN: left; FONT-FAMILY: 'Times New Roman', Times, serif; FONT-SIZE: 10pt">We review long-lived assets and certain identifiable intangibles held and used for possible impairment whenever events or changes in circumstances indicate that the carrying amount of an asset may not be recoverable. In evaluating the fair value and future benefits of its intangible assets, management performs an analysis of the anticipated undiscounted future net cash flow of the individual assets over the remaining amortization period. We recognize an impairment loss if the carrying value of the asset exceeds the expected future cash flows. During the nine months ended September 30, 2017 and the year ended December 31, 2016, there were no deemed impairments of our long-lived assets.</div></div> <div style="font-family: 'Times New Roman', Times, serif; font-size: 10pt; "> <div style="TEXT-ALIGN: left; FONT-STYLE: italic; FONT-FAMILY: 'Times New Roman', Times, serif; FONT-SIZE: 10pt"><font style="text-decoration:underline">Recent Accounting Developments</font></div><br/><div style="TEXT-ALIGN: left; FONT-FAMILY: 'Times New Roman', Times, serif; FONT-SIZE: 10pt">Accounting pronouncements issued but not effective until after September 30, 2017 are not expected to have a significant effect on our financial condition, results of operations, or cash flows.</div></div> <div style="font-family: 'Times New Roman', Times, serif; font-size: 10pt; "> <div style="TEXT-ALIGN: left; FONT-FAMILY: 'Times New Roman', Times, serif; FONT-SIZE: 10pt"><font style="text-decoration:underline">Note 3&#x2014;Intellectual Property</font></div><br/><div style="TEXT-ALIGN: left; FONT-FAMILY: 'Times New Roman', Times, serif; FONT-SIZE: 10pt">We have exclusive license agreements on thirty (30) issued and two (2) pending patents for technologies developed by researchers at the National Institutes of Health, The University of Texas MD Anderson Cancer Center, and The University of Texas Southwestern Medical Center. These patents comprise various therapeutic, diagnostic, technical and processing claims. See Note 9.</div><br/><div style="TEXT-ALIGN: left; FONT-FAMILY: 'Times New Roman', Times, serif; FONT-SIZE: 10pt">These license rights will be amortized on a straight-line basis over the estimated period of useful lives of the underlying patents or the license agreements.</div><br/></div> 30 2 <div style="font-family: 'Times New Roman', Times, serif; font-size: 10pt; "> <div style="TEXT-ALIGN: left; FONT-FAMILY: 'Times New Roman', Times, serif; FONT-SIZE: 10pt"><font style="text-decoration:underline">Note 4&#x2014;Investment Unit</font></div><br/><div style="TEXT-ALIGN: left; FONT-FAMILY: 'Times New Roman', Times, serif; FONT-SIZE: 10pt">The Texas Emerging Technology Fund (&#x201c;TETF&#x201d;) was created as an incentive for economic development to the Texas economy by providing financial support that leverages private investment for the creation of high-quality technology jobs in Texas. The award received required us to comply with certain performance conditions to ensure the monies the Company received were used for development activities in the state of Texas, and that we maintained our corporate nexus in Texas. Further, in connection with the award, the Company issued an Investment Unit to the TETF. As further described below, the Investment Unit consists of a Promissory Note and a Right to Purchase:</div><br/><div style="TEXT-ALIGN: left; FONT-STYLE: italic; FONT-FAMILY: 'Times New Roman', Times, serif; FONT-SIZE: 10pt"><font style="text-decoration:underline">Promissory Note</font></div><br/><div style="TEXT-ALIGN: left; FONT-FAMILY: 'Times New Roman', Times, serif; FONT-SIZE: 10pt">The Promissory Note is an obligation to repay the $4.5 million principal amount, with interest accrued at 8% per annum, but only if an event of default occurs prior to August 13, 2020. If no event of default occurs prior to August 13, 2020, the Promissory Note and all related interest will be cancelled.</div><br/><div style="TEXT-ALIGN: left; FONT-FAMILY: 'Times New Roman', Times, serif; FONT-SIZE: 10pt">Consistent with the stated objectives of the TETF, an event of default that would trigger the repayment obligation under the Promissory Note is our failure to maintain our principal place of business or our principal executive offices headquartered in the State of Texas (referred to as the &#x201c;Residency Requirement&#x201d;) until August 13, 2020.</div><br/><div style="TEXT-ALIGN: left; FONT-STYLE: italic; FONT-FAMILY: 'Times New Roman', Times, serif; FONT-SIZE: 10pt"><font style="text-decoration:underline">Warrant</font></div><br/><div style="TEXT-ALIGN: left; FONT-FAMILY: 'Times New Roman', Times, serif; FONT-SIZE: 10pt">The Warrant is an obligation to issue (a Right to purchase by the TETF) shares of the same class of stock to be issued in a &#x201c;First Qualifying Financing Transaction,&#x201d; at 80% of the per share transaction value (effectively a 20% discount). Alternatively, the TETF could exercise its right to purchase at any time prior to the occurrence of a First Qualifying Financial Transaction for $0.001 per share.</div><br/><div style="TEXT-ALIGN: left; FONT-FAMILY: 'Times New Roman', Times, serif; FONT-SIZE: 10pt">The Warrant included a provision that required changes in the strike price, driven by the pricing of the &#x201c;First Qualifying Financing Transaction.&#x201d; As a result, the Warrants embedded in the Investment Unit were accounted for as a derivative financial instrument and classified outside from equity under ASC 815-40-15 as the settlement adjustment from the future transaction did not permit for the strike price to be considered fixed.</div><br/><div style="TEXT-ALIGN: left; FONT-FAMILY: 'Times New Roman', Times, serif; FONT-SIZE: 10pt">On March 12, 2014, the TETF exercised its Right to Purchase for $0.001 per share, and we issued to the TETF an aggregate of 184,797 shares of our Series B preferred stock.</div><br/><div style="TEXT-ALIGN: left; FONT-STYLE: italic; FONT-FAMILY: 'Times New Roman', Times, serif; FONT-SIZE: 10pt"><font style="text-decoration:underline">Accounting for the Investment Unit</font></div><br/><div style="TEXT-ALIGN: left; FONT-FAMILY: 'Times New Roman', Times, serif; FONT-SIZE: 10pt">We accounted for the Investment Unit as a hybrid financial instrument under FASB Statement 155, and measured the Investment Unit at the amount of proceeds received from the TETF award. The First Qualifying Financial Transaction occurred during December 2013, resulting in an adjustment to the fair value of the Investment Unit in the amount of approximately $2.5 million. The TETF exercised the Warrant for $0.001 per share. We received notice of purchase from the TETF during March 2014, and issued 184,797 shares of series B Preferred Stock.</div><br/><div style="TEXT-ALIGN: left; FONT-FAMILY: 'Times New Roman', Times, serif; FONT-SIZE: 10pt">Upon exercise by the TETF of the Warrant, the remaining component within the Investment Unit was the Promissory Note. The Investment Unit was valued at zero, because our obligation to repay the Promissory Note arises from an event of default (a failure to maintain the Texas Residency Requirement), which is an event which rests entirely within our control.</div><br/></div> 4500000 0.08 2020-08-13 If no event of default occurs prior to August 13, 2020, the Promissory Note and all related interest will be cancelled. 0.80 0.20 0.001 0.001 184797 2500000 <div style="font-family: 'Times New Roman', Times, serif; font-size: 10pt; "> <div style="TEXT-ALIGN: left; FONT-FAMILY: 'Times New Roman', Times, serif; FONT-SIZE: 10pt"><font style="text-decoration:underline">Note 5&#x2014;Equity</font></div><br/><div style="TEXT-ALIGN: left; FONT-STYLE: italic; FONT-FAMILY: 'Times New Roman', Times, serif; FONT-SIZE: 10pt"><font style="text-decoration:underline">Stock Issuances</font></div><br/><div style="TEXT-ALIGN: left; FONT-FAMILY: 'Times New Roman', Times, serif; FONT-SIZE: 10pt">During the nine months ended September 30, 2017, we issued (i) 26,000 shares of Common Stock for service provided to us, valued at $918,580, and we issued (ii) 22,473 shares of Series G Preferred Stock for cash of $793,971.</div><br/><div style="TEXT-ALIGN: left; FONT-STYLE: italic; FONT-FAMILY: 'Times New Roman', Times, serif; FONT-SIZE: 10pt"><font style="text-decoration:underline">Preferred Stock</font></div><br/><div style="TEXT-ALIGN: left; FONT-FAMILY: 'Times New Roman', Times, serif; FONT-SIZE: 10pt">We have 4,500,000 shares of preferred stock authorized with a par value of $0.001. The Board has the authority to issue the shares in one or more series and to set the designations, preferences, powers and other rights, as it deems appropriate.</div><br/><div style="TEXT-ALIGN: left; FONT-FAMILY: 'Times New Roman', Times, serif; FONT-SIZE: 10pt">The Series A Preferred Stock is convertible by the holder into Voting Common Stock on a 1:1 basis, and is converted automatically upon a public offering of securities resulting in a capital raise of at least $20 million at a share price of at least $2.00 per share. The Series B through Series G Preferred Stock is convertible by the holder into Non-Voting Common Stock on a 1:1 basis, and is converted automatically into Voting Common Stock upon a public offering of securities resulting in a capital raise of at least $20 million at a share price of at least</div><br/><div style="TEXT-ALIGN: left; FONT-FAMILY: 'Times New Roman', Times, serif; FONT-SIZE: 10pt">$2.00 per share.</div><br/><div style="TEXT-ALIGN: left; FONT-FAMILY: 'Times New Roman', Times, serif; FONT-SIZE: 10pt">The Series A Preferred is voting and carries a non-cumulative dividend of $0.05 per share, if, as and when declared by the Board of Directors and carries a liquidation preference of $1.00 per share upon a &#x201c;Liquidation Event&#x201d;, as defined in our certificate of incorporation.</div><br/><div style="TEXT-ALIGN: left; FONT-FAMILY: 'Times New Roman', Times, serif; FONT-SIZE: 10pt">The Series B Preferred is nonvoting and carries a non-cumulative dividend of $1.91 per share, if, as and when declared by the Board of Directors and carries a liquidation preference, subordinate to the rights of the holders of Series A and D Preferred Stock, of $38.11 per share upon a &#x201c;Liquidation Event&#x201d;, as defined in our certificate of incorporation.</div><br/><div style="TEXT-ALIGN: left; FONT-FAMILY: 'Times New Roman', Times, serif; FONT-SIZE: 10pt">The Series C Preferred is nonvoting and carries a non-cumulative dividend of $.19 per share, if, as and when declared by the Board of Directors and carries a liquidation preference, subordinate to the rights of the holders of Series A, B and D Preferred Stock and pari passu with the rights of the holders of the Series E and F Preferred Stock, of $19.06 per share upon a &#x201c;Liquidation Event&#x201d;, as defined in our certificate of incorporation.</div><br/><div style="TEXT-ALIGN: left; FONT-FAMILY: 'Times New Roman', Times, serif; FONT-SIZE: 10pt">The Series D Preferred is voting and carries a non-cumulative dividend of $3.46 per share, if, as and when declared by the Board of Directors and carries a liquidation preference, subordinate to the rights of the holders of Series A Preferred Stock, of $69.29 per share upon a &#x201c;Liquidation Event&#x201d;, as defined in our certificate of incorporation.</div><br/><div style="TEXT-ALIGN: left; FONT-FAMILY: 'Times New Roman', Times, serif; FONT-SIZE: 10pt">The Series E Preferred is nonvoting and carries a non-cumulative dividend of $2.08 per share, if, as and when declared by the Board of Directors and carries a liquidation preference, subordinate to the rights of the holders of Series A, B and D Preferred Stock and pari passu with the rights of the holders of the Series C and E Preferred Stock, of $34.65 per share upon a &#x201c;Liquidation Event&#x201d;, as defined in our certificate of incorporation.</div><br/><div style="TEXT-ALIGN: left; FONT-FAMILY: 'Times New Roman', Times, serif; FONT-SIZE: 10pt">The Series F Preferred is nonvoting and carries a non-cumulative dividend of $1.37 per share, if, as and when declared by the Board of Directors and carries a liquidation preference, subordinate to the rights of the holders of Series A, B and D Preferred Stock and pari passu with the rights of the holders of the Series C and E Preferred Stock, of $22.87 per share upon a &#x201c;Liquidation Event&#x201d;, as defined in our certificate of incorporation.</div><br/><div style="TEXT-ALIGN: left; FONT-FAMILY: 'Times New Roman', Times, serif; FONT-SIZE: 10pt">The Series G Preferred is nonvoting and carries a non-cumulative dividend of $1.06 per share, if, as and when declared by the Board of Directors and carries a liquidation preference, subordinate to the rights of the holders of Series A, B, C, D, E, and F Preferred Stock, of $35.33 per share upon a &#x201c;Liquidation Event&#x201d;, as defined in our certificate of incorporation.</div><br/><div style="TEXT-ALIGN: left; FONT-STYLE: italic; FONT-FAMILY: 'Times New Roman', Times, serif; FONT-SIZE: 10pt"><font style="text-decoration:underline">Common Stock</font></div><br/><div style="TEXT-ALIGN: left; FONT-FAMILY: 'Times New Roman', Times, serif; FONT-SIZE: 10pt">We have 5,500,000 shares of Common Stock authorized (4,500,000 voting and 1,000,000 nonvoting) with a par value of $0.001. Each share of voting Common Stock has one vote per share for the election of directors and all other items submitted to a vote of stockholders. The Common Stock does not have cumulative voting rights, preemptive, redemption or conversion rights. For all periods presented, 25,611 shares of our total number of shares of Common Stock outstanding were nonvoting.</div><br/><div style="TEXT-ALIGN: left; FONT-STYLE: italic; FONT-FAMILY: 'Times New Roman', Times, serif; FONT-SIZE: 10pt"><font style="text-decoration:underline">Preferred Stock Purchase Warrants</font></div><br/><div style="TEXT-ALIGN: left; FONT-FAMILY: 'Times New Roman', Times, serif; FONT-SIZE: 10pt">There was no preferred stock purchase warrant activity for the nine months ended September 30, 2017.</div><br/><div style="TEXT-ALIGN: left; FONT-STYLE: italic; FONT-FAMILY: 'Times New Roman', Times, serif; FONT-SIZE: 10pt"><font style="text-decoration:underline">Common Stock Purchase Warrants</font></div><br/><div style="TEXT-ALIGN: left; FONT-FAMILY: 'Times New Roman', Times, serif; FONT-SIZE: 10pt">There was no common stock purchase warrant activity for the nine months ended September 30, 2017.</div><br/><div style="TEXT-ALIGN: left; FONT-STYLE: italic; FONT-FAMILY: 'Times New Roman', Times, serif; FONT-SIZE: 10pt"><font style="text-decoration:underline">Stock Options</font></div><br/><div style="TEXT-ALIGN: left; FONT-FAMILY: 'Times New Roman', Times, serif; FONT-SIZE: 10pt">We have outstanding stock options to purchase 393,280 shares of Common Stock that have been granted to various employees, vendors and independent contractors. These options vest over periods ranging from twelve (12) to forty-eight (48) months, are exercisable for a period of ten years, and enable the holders to purchase shares of our Common Stock at exercise prices ranging from $0.001&#x2014;$35.33. The per-share fair values of these options range from $0.001 to $17.91, based on Black-Scholes-Merton pricing models with the following assumptions: volatility (76.74%); risk-free rates (1.77%&#x2014;1.82%); and terms (3&#x2014;10 years). The weighted average remaining contractual term for the outstanding options at September 30, 2017, is 7.49 years.</div><br/><div style="TEXT-ALIGN: left; FONT-FAMILY: 'Times New Roman', Times, serif; FONT-SIZE: 10pt">There was no stock option activity for the nine months ended September 30, 2017.</div><br/></div> 26000 918580 22473 793971 4500000 0.001 The Series A Preferred Stock is convertible by the holder into Voting Common Stock on a 1:1 basis, and is converted automatically upon a public offering of securities resulting in a capital raise of at least $20 million at a share price of at least $2.00 per share. The Series B through Series G Preferred Stock is convertible by the holder into Non-Voting Common Stock on a 1:1 basis, and is converted automatically into Voting Common Stock upon a public offering of securities resulting in a capital raise of at least $20 million at a share price of at least The Series B through Series G Preferred Stock is convertible by the holder into Non-Voting Common Stock on a 1:1 basis, and is converted automatically into Voting Common Stock upon a public offering of securities resulting in a capital raise of at least $20 million at a share price of at least$2.00 per share. The Series B through Series G Preferred Stock is convertible by the holder into Non-Voting Common Stock on a 1:1 basis, and is converted automatically into Voting Common Stock upon a public offering of securities resulting in a capital raise of at least $20 million at a share price of at least$2.00 per share. The Series B through Series G Preferred Stock is convertible by the holder into Non-Voting Common Stock on a 1:1 basis, and is converted automatically into Voting Common Stock upon a public offering of securities resulting in a capital raise of at least $20 million at a share price of at least$2.00 per share. The Series B through Series G Preferred Stock is convertible by the holder into Non-Voting Common Stock on a 1:1 basis, and is converted automatically into Voting Common Stock upon a public offering of securities resulting in a capital raise of at least $20 million at a share price of at least$2.00 per share. The Series B through Series G Preferred Stock is convertible by the holder into Non-Voting Common Stock on a 1:1 basis, and is converted automatically into Voting Common Stock upon a public offering of securities resulting in a capital raise of at least $20 million at a share price of at least$2.00 per share. 0.05 1.00 1.91 38.11 0.19 19.06 3.46 69.29 2.08 34.65 1.37 22.87 1.06 35.33 4500000 1000000 Each share of voting Common Stock has one vote per share for the election of directors and all other items submitted to a vote of stockholders. 25611 393280 P12M P48M P10Y 0.001 35.33 0.001 17.91 0.7674 0.0177 0.0182 P3Y P10Y P7Y178D <div style="font-family: 'Times New Roman', Times, serif; font-size: 10pt; "> <div style="TEXT-ALIGN: left; FONT-FAMILY: 'Times New Roman', Times, serif; FONT-SIZE: 10pt"><font style="text-decoration:underline">Note 6&#x2014;Related Party Transactions</font></div><br/><div style="TEXT-ALIGN: left; FONT-STYLE: italic; FONT-FAMILY: 'Times New Roman', Times, serif; FONT-SIZE: 10pt"><font style="text-decoration:underline">Introgen Research Institute</font></div><br/><div style="TEXT-ALIGN: left; FONT-FAMILY: 'Times New Roman', Times, serif; FONT-SIZE: 10pt">Introgen Research Institute (&#x201c;IRI&#x201d;) is a Texas-based technology company, currently affiliated with Rodney Varner, our CEO.</div><br/><div style="TEXT-ALIGN: left; FONT-FAMILY: 'Times New Roman', Times, serif; FONT-SIZE: 10pt">In April 2009, prior to Mr. Varner becoming an officer and director of our Company in August 2012, we entered into an Assignment and Collaboration Agreement with IRI, providing us with the exclusive right to commercialize a portfolio of intellectual property. This agreement was amended in 2011 to include additional sublicensing of additional intellectual property made available to IRI from the University of Texas MD Anderson Cancer Center (&#x201c;UTMDACC&#x201d;).</div><br/><div style="TEXT-ALIGN: left; FONT-STYLE: italic; FONT-FAMILY: 'Times New Roman', Times, serif; FONT-SIZE: 10pt"><font style="text-decoration:underline">Confer Capital</font></div><br/><div style="TEXT-ALIGN: left; FONT-FAMILY: 'Times New Roman', Times, serif; FONT-SIZE: 10pt">Confer Capital, Inc. (&#x201c;Confer Capital&#x201d;) is a technology commercialization advisory services company affiliated with Ryan Confer, current CFO. From time to time since the Company&#x2019;s inception, Confer Capital provided strategic, financial, and executive managerial services to the Company when Ryan Confer was not considered a payroll employee. Additionally, Confer Capital has also incurred corporate expenses on our behalf and was reimbursed for these expenses. 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The trial is expected to run through the end of 2018 with a projected total cost of approximately $2 million. Payments are due and payable when invoiced throughout the clinical trial period. The agreement may be terminated at any time.</div><br/><div style="TEXT-ALIGN: left; FONT-FAMILY: 'Times New Roman', Times, serif; FONT-SIZE: 10pt">In 2009, we agreed to assume certain contractual and other obligations of IRI in consideration for the sublicense rights, expertise, and assistance associated with the assignment of certain technologies and intellectual property. 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Document And Entity Information - shares
9 Months Ended
Sep. 30, 2017
Nov. 27, 2017
Document Information [Line Items]    
Entity Registrant Name Genprex, Inc.  
Document Type 10-Q  
Current Fiscal Year End Date --12-31  
Amendment Flag false  
Entity Central Index Key 0001595248  
Entity Current Reporting Status Yes  
Entity Voluntary Filers No  
Entity Filer Category Smaller Reporting Company  
Entity Well-known Seasoned Issuer No  
Document Period End Date Sep. 30, 2017  
Document Fiscal Year Focus 2017  
Document Fiscal Period Focus Q3  
Nonvoting Common Stock [Member]    
Document Information [Line Items]    
Entity Common Stock, Shares Outstanding   25,611
Voting Common Stock [Member]    
Document Information [Line Items]    
Entity Common Stock, Shares Outstanding   333,065
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Balance Sheets - USD ($)
Sep. 30, 2017
Dec. 31, 2016
Current assets:    
Cash $ 373,945 $ 1,602,295
Prepaid expenses and other 26,812 36,533
Total current assets 400,757 1,638,828
Property and equipment, net 8,833 5,157
Other assets:    
Deposits 0 0
Deferred offering costs 559,810 25,507
Intellectual property, net 297,381 241,037
Total other assets 857,191 266,544
Total assets 1,266,781 1,910,529
Current liabilities:    
Accounts payable and accrued expenses 363,077 285,661
Other current liabilities 32,180 0
Total current liabilities 395,257 285,661
Investment unit 0 0
Commitments and contingencies
Stockholders’ equity:    
Common stock $0.001 par value: 5,500,000 shares authorized; 327,676, 307,676 and 348,676 shares issued and outstanding, respectively 355 328
Additional paid-in capital 17,655,553 15,761,362
Accumulated deficit (16,785,779) (14,138,195)
Total stockholders’ equity 871,524 1,624,868
Total liabilities and stockholders’ equity 1,266,781 1,910,529
Series A Preferred Stock [Member]    
Stockholders’ equity:    
Preferred stock 1,002 1,002
Series B Preferred Stock [Member]    
Stockholders’ equity:    
Preferred stock 208 208
Series C Preferred Stock [Member]    
Stockholders’ equity:    
Preferred stock 73 73
Series D Preferred Stock [Member]    
Stockholders’ equity:    
Preferred stock 1 1
Series E Preferred Stock [Member]    
Stockholders’ equity:    
Preferred stock 3 3
Series F Preferred Stock [Member]    
Stockholders’ equity:    
Preferred stock 4 4
Series G Preferred Stock [Member]    
Stockholders’ equity:    
Preferred stock $ 104 $ 82
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Balance Sheets (Parentheticals) - $ / shares
Sep. 30, 2017
Dec. 31, 2016
Common stock; par value (in Dollars per share) $ 0.001 $ 0.001
Common stock; shares authorized 5,500,000 5,500,000
Common stock; shares issued 353,676 327,676
Common stock; shares outstanding 353,676 327,676
Series A Preferred Stock [Member]    
Series; shares issued 1,001,667 1,001,667
Series; shares outstanding 1,001,667 1,001,667
Series B Preferred Stock [Member]    
Series; shares issued 207,917 207,917
Series; shares outstanding 207,917 207,917
Series C Preferred Stock [Member]    
Series; shares issued 73,452 73,452
Series; shares outstanding 73,452 73,452
Series D Preferred Stock [Member]    
Series; shares issued 1,443 1,443
Series; shares outstanding 1,443 1,443
Series E Preferred Stock [Member]    
Series; shares issued 2,886 2,886
Series; shares outstanding 2,886 2,886
Series F Preferred Stock [Member]    
Series; shares issued 4,008 4,008
Series; shares outstanding 4,008 4,008
Series G Preferred Stock [Member]    
Series; shares issued 103,580 81,107
Series; shares outstanding 103,580 81,107
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Statements of Operations - USD ($)
3 Months Ended 9 Months Ended
Sep. 30, 2017
Sep. 30, 2016
Sep. 30, 2017
Sep. 30, 2016
Revenues $ 0 $ 0 $ 0 $ 0
Cost and expenses:        
Depreciation 808 216 2,213 648
Research and development 55,517 89,896 228,860 225,546
General and administrative 658,797 629,747 2,416,557 2,906,898
Total costs and expenses 715,122 719,859 2,647,630 3,133,092
Operating loss (715,122) (719,859) (2,647,630) (3,133,092)
Interest Income 24 0 55 0
Income tax expense 0 0 0 0
Net loss $ (715,098) $ (719,859) $ (2,647,576) $ (3,133,092)
Net loss per share—basic and diluted (in Dollars per share) $ (2.04) $ (2.25) $ (7.77) $ (10.04)
Weighted average number of common shares— basic and diluted (in Shares) 351,176 320,176 340,764 311,985
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Statements of Cash Flows - USD ($)
3 Months Ended 9 Months Ended 12 Months Ended
Sep. 30, 2017
Sep. 30, 2016
Sep. 30, 2017
Sep. 30, 2016
Dec. 31, 2016
Cash flows from operating activities:          
Net loss $ (715,098) $ (719,859) $ (2,647,576) $ (3,133,092)  
Adjustments to reconcile net loss to net cash used in operating activities:          
Depreciation 808 216 2,213 648  
Share based compensation     1,100,328 2,316,859 $ 136,810
Changes in operating assets and liabilities:          
Accounts receivable     8,182 2,519  
Prepaid expenses and other     1,540 (15,050)  
Deferred operating costs     (534,303) 0  
Deposits     0 0  
Accounts payable and accrued expenses     109,588 428,496  
Net cash used in operating activities     (1,960,028) (399,620)  
Cash flows from investing activities:          
Additions to property and equipment     (5,998) 0  
Additions to intellectual property     (56,343) (71,887) (36,000)
Net cash used in investing activities     (62,341) (71,887)  
Cash flows from financing activities:          
Proceeds from issuances of common stock     26 0  
Proceeds from issuances of preferred stock     793,993 1,205,866  
Net cash provided by financing activities     794,019 1,205,866  
Net increase (decrease) in cash     (1,228,350) (734,359)  
Cash, beginning of period     1,602,295 234,220 234,220
Cash, end of period $ 373,945 $ 968,579 $ 373,945 $ 968,579 $ 1,602,295
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Note 1-Description of Business and Basis of Presentation
9 Months Ended
Sep. 30, 2017
Disclosure Text Block [Abstract]  
Organization, Consolidation and Presentation of Financial Statements Disclosure [Text Block]
Note 1—Description of Business and Basis of Presentation

Genprex, Inc. (“we” or “the Company”), is a privately held, clinical-stage biopharmaceutical company developing immunogene therapies for cancer. Our first product candidate, branded as Oncoprex™, is in phase II clinical trials for lung cancer patients in the United States.

We are subject to all the risks inherent in a start-up company in the biopharmaceutical industry. The biopharmaceutical industry is subject to rapid and technological change. We have numerous competitors, including major pharmaceutical and chemical companies, specialized biotechnology firms, universities and other research institutions. These competitors may succeed in developing technologies and products that are more effective than any that are being developed by us or that would render our technology and products obsolete and noncompetitive. Many of these competitors have substantially greater financial and technical resources than us. In addition, many of our competitors have significantly greater experience than us in pre-clinical testing and human clinical trials of new or improved pharmaceutical products and in obtaining FDA and other regulatory approvals on products for use in health care.

Initial Public Offering

On July 21, 2017, we filed a registration statement on Form S-1 (File No. 333-219386) relating to the initial public offering (IPO) of our common stock.  The Registration Statement, as amended, was declared effective by the Securities and Exchange Commission (SEC) on October 13, 2017.  On November 14, 2017, we filed our updated final prospectus with the SEC, relating to the sale of up to 4,500,000 shares of our common stock at a price of $5.00 per share.  The IPO is ongoing.

In connection with the completion of the IPO, all of our outstanding shares of convertible preferred stock will be converted into an aggregate of 1,394,953 shares of voting common stock (before giving effect to the forward split described below), all of our outstanding shares of non-voting common stock will be converted into an aggregate of 25,611 shares of voting common stock (before giving effect to the forward split described below), and each of our outstanding shares of voting common stock will be split and converted into 6.6841954 shares of voting common stock.  The accompanying financial statements and note to the financial statements do not give effect to these changes.

Capital Requirements, Liquidity and Going Concern Considerations

Our financial statements are prepared using the generally accepted accounting principles applicable to a going concern, which contemplates the realization of assets and liquidation of liabilities in the normal course of business. However, as shown in the accompanying financial statements, we have sustained substantial losses from operations since inception and have no current source of revenue. In addition, we have used, rather than provided, cash in our operations. We expect to continue to incur significant expenditures to further clinical trials for the commercial development of our patents.

Management recognizes that we must obtain additional resources to successfully commercialize our intellectual property. To date, we have received funding in the form of equity and debt, and plan to either continue obtaining funding through 2017 or until we have secured a capital market transaction. However, no assurances can be given that we will be successful in raising additional capital. If we are not able to timely and successfully raise additional capital, the timing of our clinical trials, financial condition and results of operations will continue to be materially affected. These financial statements do not include any adjustments relating to the recoverability and classification of recorded asset amounts and classification of liabilities that might be necessary should we be unable to continue as a going concern.

XML 14 R7.htm IDEA: XBRL DOCUMENT v3.8.0.1
Note 2-Summary of Significant Accounting Policies
9 Months Ended
Sep. 30, 2017
Accounting Policies [Abstract]  
Significant Accounting Policies [Text Block]
Note 2—Summary of Significant Accounting Policies

The financial statements have been prepared in accordance with U.S. generally accepted accounting principles (“U.S. GAAP”) and reflect all adjustments, which are of a normal and recurring nature, that are, in the opinion of management, necessary for a fair presentation of our financial position and results of operations for the related periods. The results of operations for any interim periods are not necessarily indicative of results to be expected for the full year. A summary of our significant accounting policies consistently applied in the preparation of the accompanying financial statements follows.

Restatement of Balance Sheet at December 31, 2016

Subsequent to the auditors’ issuance of their report on our December 31, 2016 financial statements, management became aware of a scrivener’s error in the terms of certain options granted, resulting in a $136,810 increase in share based compensation (accumulated deficit) and additional paid-in capital during the fourth quarter of 2016.

Use of Estimates

The preparation of our financial statements in conformity with GAAP requires us to make estimates and assumptions that affect the reported amounts of assets and liabilities and disclosure of contingent assets and liabilities at the date of the financial statements and the reported amounts of expenses during the reporting period. Actual results could differ from those estimates.

Cash and Cash Equivalents

We consider all highly liquid short-term investments with an initial maturity of three months or less to be cash equivalents. Any amounts of cash in financial institutions which exceed FDIC insured limits expose us to cash concentration risk. We have no cash equivalents, and had $118,950 and $1,351,868 in excess of FDIC insured limits of $250,000 at September 30, 2017 and December 31, 2016, respectively.

Fair Value of Financial Instruments

The carrying amounts reported in the balance sheet for cash, accounts payable and accrued expenses approximate fair value because of the immediate or short-term maturity of these financial instruments.

ASC 820 defines fair value, provides a consistent framework for measuring fair value under GAAP and expands fair value financial statement disclosure requirements. ASC 820’s valuation techniques are based on observable and unobservable inputs. Observable inputs reflect readily obtainable data from independent sources, while unobservable inputs reflect our market assumptions. ASC 820 classifies these inputs into the following hierarchy:

Level 1: Quoted prices for identical instruments in active markets

Level 2: Quoted prices for similar instruments in active markets; quoted prices for identical or similar instruments in markets that are not active; and model-derived valuations whose inputs are observable or whose significant value drivers are observable

Level 3: Instruments with primarily unobservable value drivers.

Property and Equipment

Furniture and equipment are stated at cost. Depreciation is calculated using the straight line method over the estimated useful lives of the assets, which range from three to five years. Routine maintenance and repairs are charged to expense as incurred and major renovations or improvements are capitalized.

Research and Development Materials Costs

Research and development expenditures are comprised of costs incurred to conduct research and development activities. These include payments to collaborative research partners, including wages and associated employee benefits, facilities and overhead costs. These expenditures relate to Phase 1 and 2 clinical trials and are expensed as incurred. Purchased materials to be used in future research are capitalized and included in prepaid expenses.

Awards

In 2010, we were awarded $4.5 million from the State of Texas Emerging Technology Fund (“TETF”). The award was received in two tranches of $2.25 million during 2010 and 2011. The award proceeds were used for the development and future commercialization of our nanomolecular therapy product for the treatment of cancer. In consideration for the award, we provided the TETF with an “Investment Unit”, consisting of (i) a Promissory Note (“Note”) and (ii) a right to purchase our equity shares (“Warrant”). The funds received for this award were assigned to the Investment Unit, and classified separately from equity as “mezzanine” in the balance sheet.

In 2010, we also were awarded approximately $244,500 from the U.S. Treasury Department for our QTDP Program Nanoparticle Therapy for Lung Cancer. The award was received during 2011 for our historical activities, and required no prospective expenditures. We accounted for these funds received as revenue at that time.

Intellectual Property

Intellectual property consists of external legal and related costs associated with patents and other proprietary technology acquired, licensed, or maintained by us that we believe contribute to a probable economic benefit toward such patents and activities. These legal costs incurred in connection with the patent applications and patent maintenance are capitalized. Intellectual property is stated at cost, to be amortized on a straight-line basis over the estimated useful lives of the assets.

Accounting for Stock-Based Compensation

We use the fair value-based method of accounting for stock-based compensation for options granted to employees, independent consultants and contractors. We measure options granted at fair value determined as of the grant date, and recognize the expense over the periods in which the related services are rendered based on the terms and conditions of the award. Generally, where the award only has a service condition, the requisite service period is the same as the vesting period.

Financial Instruments

We have elected the Fair Value Option to account for the Investment Unit at fair value as a combined hybrid financial instrument containing a Warrant and a Note (see Note 4). Prior to its exercise, the Warrant component was not classified within equity, as the exercise price of the warrants was affected by the market price of our stock in a future qualifying financing transaction and was not considered to be indexed to our own stock. The Note is not classified within liabilities, as our management can determine the timing of the repayment obligation, if any. As a result, the Warrant and Note that comprised the Investment Unit were aggregated and classified within the mezzanine section of the balance sheet.

Due to the contingent terms of the financial instruments, changes in the fair value of the Investment Unit were calculated and realized in earnings. There were no changes in the fair value of the Investment Unit at September 30, 2017.

Long-Lived Assets

We review long-lived assets and certain identifiable intangibles held and used for possible impairment whenever events or changes in circumstances indicate that the carrying amount of an asset may not be recoverable. In evaluating the fair value and future benefits of its intangible assets, management performs an analysis of the anticipated undiscounted future net cash flow of the individual assets over the remaining amortization period. We recognize an impairment loss if the carrying value of the asset exceeds the expected future cash flows. During the nine months ended September 30, 2017 and the year ended December 31, 2016, there were no deemed impairments of our long-lived assets.

Recent Accounting Developments

Accounting pronouncements issued but not effective until after September 30, 2017 are not expected to have a significant effect on our financial condition, results of operations, or cash flows.

XML 15 R8.htm IDEA: XBRL DOCUMENT v3.8.0.1
Note 3-Intellectual Property
9 Months Ended
Sep. 30, 2017
Disclosure Text Block [Abstract]  
Intangible Assets Disclosure [Text Block]
Note 3—Intellectual Property

We have exclusive license agreements on thirty (30) issued and two (2) pending patents for technologies developed by researchers at the National Institutes of Health, The University of Texas MD Anderson Cancer Center, and The University of Texas Southwestern Medical Center. These patents comprise various therapeutic, diagnostic, technical and processing claims. See Note 9.

These license rights will be amortized on a straight-line basis over the estimated period of useful lives of the underlying patents or the license agreements.

XML 16 R9.htm IDEA: XBRL DOCUMENT v3.8.0.1
Note 4-Investment Unit
9 Months Ended
Sep. 30, 2017
Investment Unit [Abstract]  
Investment Unit [Text Block]
Note 4—Investment Unit

The Texas Emerging Technology Fund (“TETF”) was created as an incentive for economic development to the Texas economy by providing financial support that leverages private investment for the creation of high-quality technology jobs in Texas. The award received required us to comply with certain performance conditions to ensure the monies the Company received were used for development activities in the state of Texas, and that we maintained our corporate nexus in Texas. Further, in connection with the award, the Company issued an Investment Unit to the TETF. As further described below, the Investment Unit consists of a Promissory Note and a Right to Purchase:

Promissory Note

The Promissory Note is an obligation to repay the $4.5 million principal amount, with interest accrued at 8% per annum, but only if an event of default occurs prior to August 13, 2020. If no event of default occurs prior to August 13, 2020, the Promissory Note and all related interest will be cancelled.

Consistent with the stated objectives of the TETF, an event of default that would trigger the repayment obligation under the Promissory Note is our failure to maintain our principal place of business or our principal executive offices headquartered in the State of Texas (referred to as the “Residency Requirement”) until August 13, 2020.

Warrant

The Warrant is an obligation to issue (a Right to purchase by the TETF) shares of the same class of stock to be issued in a “First Qualifying Financing Transaction,” at 80% of the per share transaction value (effectively a 20% discount). Alternatively, the TETF could exercise its right to purchase at any time prior to the occurrence of a First Qualifying Financial Transaction for $0.001 per share.

The Warrant included a provision that required changes in the strike price, driven by the pricing of the “First Qualifying Financing Transaction.” As a result, the Warrants embedded in the Investment Unit were accounted for as a derivative financial instrument and classified outside from equity under ASC 815-40-15 as the settlement adjustment from the future transaction did not permit for the strike price to be considered fixed.

On March 12, 2014, the TETF exercised its Right to Purchase for $0.001 per share, and we issued to the TETF an aggregate of 184,797 shares of our Series B preferred stock.

Accounting for the Investment Unit

We accounted for the Investment Unit as a hybrid financial instrument under FASB Statement 155, and measured the Investment Unit at the amount of proceeds received from the TETF award. The First Qualifying Financial Transaction occurred during December 2013, resulting in an adjustment to the fair value of the Investment Unit in the amount of approximately $2.5 million. The TETF exercised the Warrant for $0.001 per share. We received notice of purchase from the TETF during March 2014, and issued 184,797 shares of series B Preferred Stock.

Upon exercise by the TETF of the Warrant, the remaining component within the Investment Unit was the Promissory Note. The Investment Unit was valued at zero, because our obligation to repay the Promissory Note arises from an event of default (a failure to maintain the Texas Residency Requirement), which is an event which rests entirely within our control.

XML 17 R10.htm IDEA: XBRL DOCUMENT v3.8.0.1
Note 5-Equity
9 Months Ended
Sep. 30, 2017
Stockholders' Equity Note [Abstract]  
Stockholders' Equity Note Disclosure [Text Block]
Note 5—Equity

Stock Issuances

During the nine months ended September 30, 2017, we issued (i) 26,000 shares of Common Stock for service provided to us, valued at $918,580, and we issued (ii) 22,473 shares of Series G Preferred Stock for cash of $793,971.

Preferred Stock

We have 4,500,000 shares of preferred stock authorized with a par value of $0.001. The Board has the authority to issue the shares in one or more series and to set the designations, preferences, powers and other rights, as it deems appropriate.

The Series A Preferred Stock is convertible by the holder into Voting Common Stock on a 1:1 basis, and is converted automatically upon a public offering of securities resulting in a capital raise of at least $20 million at a share price of at least $2.00 per share. The Series B through Series G Preferred Stock is convertible by the holder into Non-Voting Common Stock on a 1:1 basis, and is converted automatically into Voting Common Stock upon a public offering of securities resulting in a capital raise of at least $20 million at a share price of at least

$2.00 per share.

The Series A Preferred is voting and carries a non-cumulative dividend of $0.05 per share, if, as and when declared by the Board of Directors and carries a liquidation preference of $1.00 per share upon a “Liquidation Event”, as defined in our certificate of incorporation.

The Series B Preferred is nonvoting and carries a non-cumulative dividend of $1.91 per share, if, as and when declared by the Board of Directors and carries a liquidation preference, subordinate to the rights of the holders of Series A and D Preferred Stock, of $38.11 per share upon a “Liquidation Event”, as defined in our certificate of incorporation.

The Series C Preferred is nonvoting and carries a non-cumulative dividend of $.19 per share, if, as and when declared by the Board of Directors and carries a liquidation preference, subordinate to the rights of the holders of Series A, B and D Preferred Stock and pari passu with the rights of the holders of the Series E and F Preferred Stock, of $19.06 per share upon a “Liquidation Event”, as defined in our certificate of incorporation.

The Series D Preferred is voting and carries a non-cumulative dividend of $3.46 per share, if, as and when declared by the Board of Directors and carries a liquidation preference, subordinate to the rights of the holders of Series A Preferred Stock, of $69.29 per share upon a “Liquidation Event”, as defined in our certificate of incorporation.

The Series E Preferred is nonvoting and carries a non-cumulative dividend of $2.08 per share, if, as and when declared by the Board of Directors and carries a liquidation preference, subordinate to the rights of the holders of Series A, B and D Preferred Stock and pari passu with the rights of the holders of the Series C and E Preferred Stock, of $34.65 per share upon a “Liquidation Event”, as defined in our certificate of incorporation.

The Series F Preferred is nonvoting and carries a non-cumulative dividend of $1.37 per share, if, as and when declared by the Board of Directors and carries a liquidation preference, subordinate to the rights of the holders of Series A, B and D Preferred Stock and pari passu with the rights of the holders of the Series C and E Preferred Stock, of $22.87 per share upon a “Liquidation Event”, as defined in our certificate of incorporation.

The Series G Preferred is nonvoting and carries a non-cumulative dividend of $1.06 per share, if, as and when declared by the Board of Directors and carries a liquidation preference, subordinate to the rights of the holders of Series A, B, C, D, E, and F Preferred Stock, of $35.33 per share upon a “Liquidation Event”, as defined in our certificate of incorporation.

Common Stock

We have 5,500,000 shares of Common Stock authorized (4,500,000 voting and 1,000,000 nonvoting) with a par value of $0.001. Each share of voting Common Stock has one vote per share for the election of directors and all other items submitted to a vote of stockholders. The Common Stock does not have cumulative voting rights, preemptive, redemption or conversion rights. For all periods presented, 25,611 shares of our total number of shares of Common Stock outstanding were nonvoting.

Preferred Stock Purchase Warrants

There was no preferred stock purchase warrant activity for the nine months ended September 30, 2017.

Common Stock Purchase Warrants

There was no common stock purchase warrant activity for the nine months ended September 30, 2017.

Stock Options

We have outstanding stock options to purchase 393,280 shares of Common Stock that have been granted to various employees, vendors and independent contractors. These options vest over periods ranging from twelve (12) to forty-eight (48) months, are exercisable for a period of ten years, and enable the holders to purchase shares of our Common Stock at exercise prices ranging from $0.001—$35.33. The per-share fair values of these options range from $0.001 to $17.91, based on Black-Scholes-Merton pricing models with the following assumptions: volatility (76.74%); risk-free rates (1.77%—1.82%); and terms (3—10 years). The weighted average remaining contractual term for the outstanding options at September 30, 2017, is 7.49 years.

There was no stock option activity for the nine months ended September 30, 2017.

XML 18 R11.htm IDEA: XBRL DOCUMENT v3.8.0.1
Note 6-Related Party Transactions
9 Months Ended
Sep. 30, 2017
Related Party Transactions [Abstract]  
Related Party Transactions Disclosure [Text Block]
Note 6—Related Party Transactions

Introgen Research Institute

Introgen Research Institute (“IRI”) is a Texas-based technology company, currently affiliated with Rodney Varner, our CEO.

In April 2009, prior to Mr. Varner becoming an officer and director of our Company in August 2012, we entered into an Assignment and Collaboration Agreement with IRI, providing us with the exclusive right to commercialize a portfolio of intellectual property. This agreement was amended in 2011 to include additional sublicensing of additional intellectual property made available to IRI from the University of Texas MD Anderson Cancer Center (“UTMDACC”).

Confer Capital

Confer Capital, Inc. (“Confer Capital”) is a technology commercialization advisory services company affiliated with Ryan Confer, current CFO. From time to time since the Company’s inception, Confer Capital provided strategic, financial, and executive managerial services to the Company when Ryan Confer was not considered a payroll employee. Additionally, Confer Capital has also incurred corporate expenses on our behalf and was reimbursed for these expenses. Mr. Confer provided $65,000 of consulting services to the Company during 2016 while not on Company payroll. These services were booked in account payable when the service period concluded in August 2016 and paid out in December 2016.

XML 19 R12.htm IDEA: XBRL DOCUMENT v3.8.0.1
Note 7-Commitments and Contingencies
9 Months Ended
Sep. 30, 2017
Commitments and Contingencies Disclosure [Abstract]  
Commitments and Contingencies Disclosure [Text Block]
Note 7—Commitments and Contingencies

Commitments

We have entered into a clinical trial agreement with the University of Texas MD Anderson Cancer Center to administer a phase I/II clinical trial, combining FUS1-nanoparticles and Erlotinib in Stage IV lung cancer patients. The trial is expected to run through the end of 2018 with a projected total cost of approximately $2 million. Payments are due and payable when invoiced throughout the clinical trial period. The agreement may be terminated at any time.

In 2009, we agreed to assume certain contractual and other obligations of IRI in consideration for the sublicense rights, expertise, and assistance associated with the assignment of certain technologies and intellectual property. We also agreed to pay royalties of one percent (1%) on sales of resulting Licensed Products, for a period of

21 years following the termination of the last of the MD Anderson License Agreement and Sublicense Agreement, to IRI and we assumed patent prosecution costs and an annual minimum royalty of $20,000 payable to the National Institutes of Health (“NIH”).

Our $191,393 payment obligation to the National Institutes of Health (“NIH”) represented a current obligation, of which $15,393 of 2016 patent prosecution costs were paid in the fourth quarter of 2016 and $176,000 was included in Accounts Payable at December 31, 2016 (consisting of accrued annual royalties of $140,000 and patent costs of $36,000). During the first quarter of 2017, we modified the terms of our accrued royalty obligation to NIH. Under the modified agreement, NIH agreed to extinguish $120,000 of the accrued royalties payable to them in consideration for payment by us of (i) accrued patent costs of $36,000, (ii) a royalty payment of $20,000, and (iii) a contingent payment of $240,000, increasing at $20,000 per year starting in 2018, to be paid upon our receipt of FDA approval. The payments for the patent costs of $36,000 and royalties of $20,000 were paid during the second quarter of 2017.

As a result of our modified agreement with the NIH, we have recognized the exchange of the $120,000 fixed obligation for the $240,000 contingent obligation as a $120,000 reduction to intellectual property expense (classified within General and Administrative Expense) during the first quarter of 2017. The $240,000 contingent obligation (and related expense) will be recognized when we obtain regulatory approval (the event that triggers the payment obligation).

Contingencies

From time to time we may become subject to threatened and/or asserted claims arising in the ordinary course of our business. Management is not aware of any matters, either individually or in the aggregate, that are reasonably likely to have a material impact on our Company’s financial condition, results of operations or liquidity.

XML 20 R13.htm IDEA: XBRL DOCUMENT v3.8.0.1
Note 8-Income Taxes
9 Months Ended
Sep. 30, 2017
Income Tax Disclosure [Abstract]  
Income Tax Disclosure [Text Block]
Note 8—Income Taxes

The provision for income taxes differs from the amount computed by applying the statutory federal income tax rate to income before provision for income taxes. The sources and tax effects of the differences are as follows:

Income tax provisions at the federal statutory rate
   
34
%
Effect of operating losses
   
-34
%
 
   
0
%

At December 31, 2016, we have a net operating loss carryforward of approximately $6.8 million for Federal and state purposes. This loss will be available to offset future taxable income. If not used, this carryforward will begin to expire in 2029. The deferred tax asset relating to the operating loss carryforward has been fully reserved at September 30, 2017 and December 31, 2016 and 2015. The principal differences between the operating loss for income tax purposes and reporting purposes are shares issued for services and share-based compensation and a temporary difference in depreciation expense.

XML 21 R14.htm IDEA: XBRL DOCUMENT v3.8.0.1
Note 9-Subsequent Events
9 Months Ended
Sep. 30, 2017
Subsequent Events [Abstract]  
Subsequent Events [Text Block]
Note 9—Subsequent Events

During October 2017, we received an informal demand from a former financial advisor, claiming that it is entitled to a warrant to purchase shares of common stock equal to three percent of our outstanding shares as of December 1, 2015. We believe this asserted claim lacks merit, and we intend to defend the claim vigorously.

XML 22 R15.htm IDEA: XBRL DOCUMENT v3.8.0.1
Accounting Policies, by Policy (Policies)
9 Months Ended
Sep. 30, 2017
Accounting Policies [Abstract]  
Use of Estimates, Policy [Policy Text Block]
Use of Estimates

The preparation of our financial statements in conformity with GAAP requires us to make estimates and assumptions that affect the reported amounts of assets and liabilities and disclosure of contingent assets and liabilities at the date of the financial statements and the reported amounts of expenses during the reporting period. Actual results could differ from those estimates.
Cash and Cash Equivalents, Policy [Policy Text Block]
Cash and Cash Equivalents

We consider all highly liquid short-term investments with an initial maturity of three months or less to be cash equivalents. Any amounts of cash in financial institutions which exceed FDIC insured limits expose us to cash concentration risk. We have no cash equivalents, and had $118,950 and $1,351,868 in excess of FDIC insured limits of $250,000 at September 30, 2017 and December 31, 2016, respectively.
Fair Value of Financial Instruments, Policy [Policy Text Block]
Fair Value of Financial Instruments

The carrying amounts reported in the balance sheet for cash, accounts payable and accrued expenses approximate fair value because of the immediate or short-term maturity of these financial instruments.

ASC 820 defines fair value, provides a consistent framework for measuring fair value under GAAP and expands fair value financial statement disclosure requirements. ASC 820’s valuation techniques are based on observable and unobservable inputs. Observable inputs reflect readily obtainable data from independent sources, while unobservable inputs reflect our market assumptions. ASC 820 classifies these inputs into the following hierarchy:

Level 1: Quoted prices for identical instruments in active markets

Level 2: Quoted prices for similar instruments in active markets; quoted prices for identical or similar instruments in markets that are not active; and model-derived valuations whose inputs are observable or whose significant value drivers are observable

Level 3: Instruments with primarily unobservable value drivers.
Property, Plant and Equipment, Policy [Policy Text Block]
Property and Equipment

Furniture and equipment are stated at cost. Depreciation is calculated using the straight line method over the estimated useful lives of the assets, which range from three to five years. Routine maintenance and repairs are charged to expense as incurred and major renovations or improvements are capitalized.
Research and Development Expense, Policy [Policy Text Block]
Research and Development Materials Costs

Research and development expenditures are comprised of costs incurred to conduct research and development activities. These include payments to collaborative research partners, including wages and associated employee benefits, facilities and overhead costs. These expenditures relate to Phase 1 and 2 clinical trials and are expensed as incurred. Purchased materials to be used in future research are capitalized and included in prepaid expenses.
Award, Policy [Policy Text Block]
Awards

In 2010, we were awarded $4.5 million from the State of Texas Emerging Technology Fund (“TETF”). The award was received in two tranches of $2.25 million during 2010 and 2011. The award proceeds were used for the development and future commercialization of our nanomolecular therapy product for the treatment of cancer. In consideration for the award, we provided the TETF with an “Investment Unit”, consisting of (i) a Promissory Note (“Note”) and (ii) a right to purchase our equity shares (“Warrant”). The funds received for this award were assigned to the Investment Unit, and classified separately from equity as “mezzanine” in the balance sheet.

In 2010, we also were awarded approximately $244,500 from the U.S. Treasury Department for our QTDP Program Nanoparticle Therapy for Lung Cancer. The award was received during 2011 for our historical activities, and required no prospective expenditures. We accounted for these funds received as revenue at that time.
Intangible Assets, Finite-Lived, Policy [Policy Text Block]
Intellectual Property

Intellectual property consists of external legal and related costs associated with patents and other proprietary technology acquired, licensed, or maintained by us that we believe contribute to a probable economic benefit toward such patents and activities. These legal costs incurred in connection with the patent applications and patent maintenance are capitalized. Intellectual property is stated at cost, to be amortized on a straight-line basis over the estimated useful lives of the assets.
Share-based Compensation, Option and Incentive Plans Policy [Policy Text Block]
Accounting for Stock-Based Compensation

We use the fair value-based method of accounting for stock-based compensation for options granted to employees, independent consultants and contractors. We measure options granted at fair value determined as of the grant date, and recognize the expense over the periods in which the related services are rendered based on the terms and conditions of the award. Generally, where the award only has a service condition, the requisite service period is the same as the vesting period.
Fair Value Measurement, Policy [Policy Text Block]
Financial Instruments

We have elected the Fair Value Option to account for the Investment Unit at fair value as a combined hybrid financial instrument containing a Warrant and a Note (see Note 4). Prior to its exercise, the Warrant component was not classified within equity, as the exercise price of the warrants was affected by the market price of our stock in a future qualifying financing transaction and was not considered to be indexed to our own stock. The Note is not classified within liabilities, as our management can determine the timing of the repayment obligation, if any. As a result, the Warrant and Note that comprised the Investment Unit were aggregated and classified within the mezzanine section of the balance sheet.

Due to the contingent terms of the financial instruments, changes in the fair value of the Investment Unit were calculated and realized in earnings. There were no changes in the fair value of the Investment Unit at September 30, 2017.
Impairment or Disposal of Long-Lived Assets, Policy [Policy Text Block]
Long-Lived Assets

We review long-lived assets and certain identifiable intangibles held and used for possible impairment whenever events or changes in circumstances indicate that the carrying amount of an asset may not be recoverable. In evaluating the fair value and future benefits of its intangible assets, management performs an analysis of the anticipated undiscounted future net cash flow of the individual assets over the remaining amortization period. We recognize an impairment loss if the carrying value of the asset exceeds the expected future cash flows. During the nine months ended September 30, 2017 and the year ended December 31, 2016, there were no deemed impairments of our long-lived assets.
New Accounting Pronouncements, Policy [Policy Text Block]
Recent Accounting Developments

Accounting pronouncements issued but not effective until after September 30, 2017 are not expected to have a significant effect on our financial condition, results of operations, or cash flows.
XML 23 R16.htm IDEA: XBRL DOCUMENT v3.8.0.1
Note 8-Income Taxes (Tables)
9 Months Ended
Sep. 30, 2017
Income Tax Disclosure [Abstract]  
Schedule of Effective Income Tax Rate Reconciliation [Table Text Block]
The provision for income taxes differs from the amount computed by applying the statutory federal income tax rate to income before provision for income taxes. The sources and tax effects of the differences are as follows:

Income tax provisions at the federal statutory rate
   
34
%
Effect of operating losses
   
-34
%
 
   
0
%
XML 24 R17.htm IDEA: XBRL DOCUMENT v3.8.0.1
Note 1-Description of Business and Basis of Presentation (Details)
9 Months Ended
Jul. 21, 2017
shares
Sep. 30, 2017
Nov. 14, 2017
$ / shares
shares
Note 1-Description of Business and Basis of Presentation (Details) [Line Items]      
Sale of Stock, Price Per Share (in Dollars per share) | $ / shares     $ 5.00
Stockholders' Equity Note, Stock Split, Conversion Ratio   6.6841954  
Common Stock Relating to Initial Public Offering [Member]      
Note 1-Description of Business and Basis of Presentation (Details) [Line Items]      
Common Stock, Capital Shares Reserved for Future Issuance     4,500,000
Preferred Stock [Member]      
Note 1-Description of Business and Basis of Presentation (Details) [Line Items]      
Conversion of Stock, Shares Issued 1,394,953    
Common Stock [Member]      
Note 1-Description of Business and Basis of Presentation (Details) [Line Items]      
Conversion of Stock, Shares Issued 25,611    
XML 25 R18.htm IDEA: XBRL DOCUMENT v3.8.0.1
Note 2-Summary of Significant Accounting Policies (Details)
9 Months Ended 12 Months Ended
Sep. 30, 2017
USD ($)
Sep. 30, 2016
USD ($)
Dec. 31, 2016
USD ($)
Dec. 31, 2011
USD ($)
Dec. 31, 2010
USD ($)
Note 2-Summary of Significant Accounting Policies (Details) [Line Items]          
Share-based Compensation $ 1,100,328 $ 2,316,859 $ 136,810    
Cash, Uninsured Amount 118,950   $ 1,351,868    
Cash, FDIC Insured Amount 250,000        
Debt Instrument, Face Amount $ 4,500,000        
State of Texas Emerging Fund ("TETF") [Member]          
Note 2-Summary of Significant Accounting Policies (Details) [Line Items]          
Debt Instrument, Face Amount         $ 4,500,000
Number of Tranches         2
Proceeds from Other Debt       $ 2,250,000 $ 2,250,000
U.S. Treasury Department [Member]          
Note 2-Summary of Significant Accounting Policies (Details) [Line Items]          
Proceeds from Award         $ 244,500
Minimum [Member]          
Note 2-Summary of Significant Accounting Policies (Details) [Line Items]          
Property, Plant and Equipment, Useful Life 3 years        
Maximum [Member]          
Note 2-Summary of Significant Accounting Policies (Details) [Line Items]          
Property, Plant and Equipment, Useful Life 5 years        
XML 26 R19.htm IDEA: XBRL DOCUMENT v3.8.0.1
Note 3-Intellectual Property (Details)
9 Months Ended
Sep. 30, 2017
Disclosure Text Block [Abstract]  
Number of Patents 30
Number of Pending Patents 2
XML 27 R20.htm IDEA: XBRL DOCUMENT v3.8.0.1
Note 4-Investment Unit (Details) - USD ($)
9 Months Ended 12 Months Ended
Mar. 12, 2014
Sep. 30, 2017
Dec. 31, 2013
Dec. 31, 2016
Note 4-Investment Unit (Details) [Line Items]        
Debt Instrument, Face Amount   $ 4,500,000    
Debt Instrument, Interest Rate, Stated Percentage   8.00%    
Debt Instrument, Maturity Date   Aug. 13, 2020    
Debt Instrument, Description   If no event of default occurs prior to August 13, 2020, the Promissory Note and all related interest will be cancelled.    
Warrant, Right to Purchase, Percentage   80.00%    
Warrant, Discount Rate   20.00%    
Class of Warrant or Right, Exercise Price of Warrants or Rights $ 0.001 $ 0.001    
Fair Value Adjustment of Warrants     $ 2,500,000  
undefined   $ 0   $ 0
Series B Preferred Stock [Member]        
Note 4-Investment Unit (Details) [Line Items]        
Stock Issued During Period, Shares, New Issues 184,797      
XML 28 R21.htm IDEA: XBRL DOCUMENT v3.8.0.1
Note 5-Equity (Details) - USD ($)
9 Months Ended
Mar. 12, 2014
Sep. 30, 2017
Dec. 31, 2016
Note 5-Equity (Details) [Line Items]      
Stock Issued During Period, Shares, Issued for Services (in Shares)   26,000  
Stock Issued During Period, Value, Issued for Services (in Dollars)   $ 918,580  
Preferred Stock, Shares Authorized (in Shares)   4,500,000  
Preferred Stock, Par or Stated Value Per Share   $ 0.001  
Common Stock, Shares Authorized (in Shares)   5,500,000 5,500,000
Common Stock, Par or Stated Value Per Share   $ 0.001 $ 0.001
Common Stock, Voting Rights   Each share of voting Common Stock has one vote per share for the election of directors and all other items submitted to a vote of stockholders.  
Common Stock, Shares, Outstanding (in Shares)   353,676 327,676
Share-based Compensation Arrangement by Share-based Payment Award, Options, Outstanding, Number (in Shares)   393,280  
Share-based Compensation Arrangement by Share-based Payment Award, Expiration Period   10 years  
Share-based Compensation Arrangement by Share-based Payment Award, Fair Value Assumptions, Expected Volatility Rate   76.74%  
Share-based Compensation Arrangement by Share-based Payment Award, Fair Value Assumptions, Risk Free Interest Rate, Minimum   1.77%  
Share-based Compensation Arrangement by Share-based Payment Award, Fair Value Assumptions, Risk Free Interest Rate, Maximum   1.82%  
Share-based Compensation Arrangement by Share-based Payment Award, Options, Outstanding, Weighted Average Remaining Contractual Term   7 years 178 days  
Series G Preferred Stock [Member]      
Note 5-Equity (Details) [Line Items]      
Stock Issued During Period, Shares, New Issues (in Shares)   22,473  
Stock Issued During Period, Value, New Issues (in Dollars)   $ 793,971  
Preferred Stock, Conversion Basis   The Series B through Series G Preferred Stock is convertible by the holder into Non-Voting Common Stock on a 1:1 basis, and is converted automatically into Voting Common Stock upon a public offering of securities resulting in a capital raise of at least $20 million at a share price of at least$2.00 per share.  
Preferred Stock, Dividend Rate, Per-Dollar-Amount   $ 1.06  
Preferred Stock, Liquidation Preference Per Share   $ 35.33  
Series A Preferred Stock [Member]      
Note 5-Equity (Details) [Line Items]      
Preferred Stock, Conversion Basis   The Series A Preferred Stock is convertible by the holder into Voting Common Stock on a 1:1 basis, and is converted automatically upon a public offering of securities resulting in a capital raise of at least $20 million at a share price of at least $2.00 per share.  
Preferred Stock, Dividend Rate, Per-Dollar-Amount   $ 0.05  
Preferred Stock, Liquidation Preference Per Share   $ 1.00  
Series D Preferred Stock [Member]      
Note 5-Equity (Details) [Line Items]      
Preferred Stock, Conversion Basis   The Series B through Series G Preferred Stock is convertible by the holder into Non-Voting Common Stock on a 1:1 basis, and is converted automatically into Voting Common Stock upon a public offering of securities resulting in a capital raise of at least $20 million at a share price of at least  
Preferred Stock, Dividend Rate, Per-Dollar-Amount   $ 3.46  
Preferred Stock, Liquidation Preference Per Share   $ 69.29  
Series B Preferred Stock [Member]      
Note 5-Equity (Details) [Line Items]      
Stock Issued During Period, Shares, New Issues (in Shares) 184,797    
Preferred Stock, Conversion Basis   The Series B through Series G Preferred Stock is convertible by the holder into Non-Voting Common Stock on a 1:1 basis, and is converted automatically into Voting Common Stock upon a public offering of securities resulting in a capital raise of at least $20 million at a share price of at least$2.00 per share.  
Preferred Stock, Dividend Rate, Per-Dollar-Amount   $ 1.91  
Preferred Stock, Liquidation Preference Per Share   $ 38.11  
Series C Preferred Stock [Member]      
Note 5-Equity (Details) [Line Items]      
Preferred Stock, Conversion Basis   The Series B through Series G Preferred Stock is convertible by the holder into Non-Voting Common Stock on a 1:1 basis, and is converted automatically into Voting Common Stock upon a public offering of securities resulting in a capital raise of at least $20 million at a share price of at least$2.00 per share.  
Preferred Stock, Dividend Rate, Per-Dollar-Amount   $ 0.19  
Preferred Stock, Liquidation Preference Per Share   $ 19.06  
Series E Preferred Stock [Member]      
Note 5-Equity (Details) [Line Items]      
Preferred Stock, Conversion Basis   The Series B through Series G Preferred Stock is convertible by the holder into Non-Voting Common Stock on a 1:1 basis, and is converted automatically into Voting Common Stock upon a public offering of securities resulting in a capital raise of at least $20 million at a share price of at least$2.00 per share.  
Preferred Stock, Dividend Rate, Per-Dollar-Amount   $ 2.08  
Preferred Stock, Liquidation Preference Per Share   $ 34.65  
Series F Preferred Stock [Member]      
Note 5-Equity (Details) [Line Items]      
Preferred Stock, Conversion Basis   The Series B through Series G Preferred Stock is convertible by the holder into Non-Voting Common Stock on a 1:1 basis, and is converted automatically into Voting Common Stock upon a public offering of securities resulting in a capital raise of at least $20 million at a share price of at least$2.00 per share.  
Preferred Stock, Dividend Rate, Per-Dollar-Amount   $ 1.37  
Preferred Stock, Liquidation Preference Per Share   $ 22.87  
Voting Common Stock [Member]      
Note 5-Equity (Details) [Line Items]      
Common Stock, Shares Authorized (in Shares)   4,500,000  
Nonvoting Common Stock [Member]      
Note 5-Equity (Details) [Line Items]      
Common Stock, Shares Authorized (in Shares)   1,000,000  
Common Stock, Shares, Outstanding (in Shares)   25,611  
Minimum [Member]      
Note 5-Equity (Details) [Line Items]      
Share-based Compensation Arrangement by Share-based Payment Award, Award Vesting Period   12 months  
Share-based Compensation Arrangement by Share-based Payment Award, Options, Outstanding, Weighted Average Exercise Price   $ 0.001  
Share-based Compensation Arrangement by Share-based Payment Award, Options, Vested, Weighted Average Grant Date Fair Value   $ 0.001  
Share-based Compensation Arrangement by Share-based Payment Award, Fair Value Assumptions, Expected Term   3 years  
Maximum [Member]      
Note 5-Equity (Details) [Line Items]      
Share-based Compensation Arrangement by Share-based Payment Award, Award Vesting Period   48 months  
Share-based Compensation Arrangement by Share-based Payment Award, Options, Outstanding, Weighted Average Exercise Price   $ 35.33  
Share-based Compensation Arrangement by Share-based Payment Award, Options, Vested, Weighted Average Grant Date Fair Value   $ 17.91  
Share-based Compensation Arrangement by Share-based Payment Award, Fair Value Assumptions, Expected Term   10 years  
XML 29 R22.htm IDEA: XBRL DOCUMENT v3.8.0.1
Note 6-Related Party Transactions (Details)
12 Months Ended
Dec. 31, 2016
USD ($)
Chief Financial Officer [Member]  
Note 6-Related Party Transactions (Details) [Line Items]  
Related Party Transaction, Amounts of Transaction $ 65,000
XML 30 R23.htm IDEA: XBRL DOCUMENT v3.8.0.1
Note 7-Commitments and Contingencies (Details) - USD ($)
3 Months Ended 9 Months Ended 12 Months Ended
Jun. 30, 2017
Mar. 31, 2017
Sep. 30, 2017
Sep. 30, 2016
Dec. 31, 2016
Commitments and Contingencies Disclosure [Abstract]          
Long-term Contract, Estimated Total Cost     $ 2,000,000    
Royalty on Sales, Percentage     1.00%    
Royalty, Term     21 years    
Royalty Payment, Annual Minimum     $ 20,000    
Other Commitment     191,393    
Legal Fees         $ 15,393
Accounts Payable, Other, Current         176,000
Accrued Royalties, Current         140,000
Payments to Acquire Intangible Assets     $ 56,343 $ 71,887 $ 36,000
Extinguishment of Debt, Amount   $ 120,000      
Other Expenses $ 36,000        
Payments for Royalties 20,000        
Payment for Contingent Consideration Liability, Operating Activities 240,000        
Contingent Payments, Annual Increase $ 20,000        
Finite-Lived Intangible Assets, Period Increase (Decrease)   $ (120,000)      
XML 31 R24.htm IDEA: XBRL DOCUMENT v3.8.0.1
Note 8-Income Taxes (Details)
$ in Millions
Dec. 31, 2016
USD ($)
Income Tax Disclosure [Abstract]  
Operating Loss Carryforwards $ 6.8
XML 32 R25.htm IDEA: XBRL DOCUMENT v3.8.0.1
Note 8-Income Taxes (Details) - Schedule of Effective Income Tax Rate Reconciliation
9 Months Ended
Sep. 30, 2017
Schedule of Effective Income Tax Rate Reconciliation [Abstract]  
Income tax provisions at the federal statutory rate 34.00%
Effect of operating losses (34.00%)
0.00%
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