X0306 4 2022-05-18 0 0001595097 Corbus Pharmaceuticals Holdings, Inc. CRBP 0001329585 HOLMER ALAN F C/O CORBUS PHARMACEUTICALS HOLDINGS, INC 500 RIVER RIDGE DRIVE NORWOOD MA 02062 1 0 0 0 Stock Option(right to buy) 0.33 2022-05-18 4 A 0 79600 0.00 A 2032-05-18 Common Stock 79600 79600 D The option award was made in accordance with the terms of the issuer's 2014 Equity Compensation Plan. The option will vest in equal monthly installments over the course of 12 months beginning on the date of grant. /s/ Alan Holmer 2022-05-19