Condensed Consolidated Statements of Cash Flows (Unaudited) - USD ($) $ in Thousands	3 Months Ended
	Mar. 31, 2023	Mar. 31, 2022
Cash flows from operating activities
Net loss	$ (35,467)	$ (42,077)
Adjustments to reconcile net loss to net cash used in operating activities:
Stock-based compensation expense	12,535	11,661
NonCashLeaseExpense		16
Depreciation and amortization expense	104	7
Accretion of premium and discounts on marketable securities	(3,087)
Changes in operating assets and liabilities:
Prepaid expenses and other current assets	2,311	275
Other assets	(197)
Accounts payable	(1,851)	(877)
Accrued expenses and other liabilities	(4,157)	(28,014)
Operating lease liabilities	(41)
Net cash used in operating activities	(29,850)	(59,009)
Cash flows from investing activities
Additions to property and equipment		(44)
Purchases of marketable securities	(156,626)
Sales and maturities of marketable securities	181,106
Net cash provided by (used in) investing activities	24,480	(44)
Cash flows from financing activities
Proceeds from issuance of common stock for exercise of stock options		223
Proceeds from issuance of common stock under ESPP	165
Net cash provided by financing activities	165	223
Net decrease in cash, cash equivalents and restricted cash	(5,205)	(58,830)
Cash, cash equivalents and restricted cash at the beginning of period	188,658	764,680
Cash, cash equivalents and restricted cash at the end of period	183,453	705,850
Cash, cash equivalents and restricted cash at the end of period:
Cash and cash equivalents	183,255	705,545
Restricted cash	198	305
Cash, cash equivalents and restricted cash at the end of period	$ 183,453	705,850
Supplemental disclosure of noncash financing activities
Property and equipment purchases unpaid at period end		702
Right of use assets obtained in exchange for operating lease liabilities		$ 2,938