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Stock-based Compensation - Summary of Stock Options Activity (Details) - USD ($)
$ / shares in Units, $ in Thousands
12 Months Ended
Dec. 31, 2022
Dec. 31, 2021
Number of Shares    
Number of Shares, Outstanding 10,516,972  
Number of Shares, Granted 3,884,917  
Number of Shares, Exercised (155,873)  
Number of Shares, Cancelled (613,738)  
Number of Shares, Outstanding 13,632,278 10,516,972
Number of Shares, Vested and expected to vest 13,632,278  
Number of Shares, Vested and exercisable 7,459,247  
Weighted Average Exercise Price Per Share    
Weighted Average Exercise Price Per Share, Outstanding $ 22.87  
Weighted Average Exercise Price Per Share, Granted 7.08  
Weighted Average Exercise Price Per Share, Exercised 1.48  
Weighted Average Exercise Price Per Share, Cancelled 25.87  
Weighted Average Exercise Price Per Share, Outstanding 18.48 $ 22.87
Weighted Average Exercise Price Per Share, Vested and expected to vest 18.48  
Weighted Average Exercise Price Per Share, Vested and exercisable $ 16.11  
Weighted Average Remaining Contractual Term and Aggregate Intrinsic Value    
Weighted Average Remaining Contractual Term (years), Outstanding 7 years 8 months 12 days 8 years 1 month 6 days
Weighted Average Remaining Contractual Term (years), Vested and expected to vest 7 years 8 months 12 days  
Weighted Average Remaining Contractual Term (years), Vested and exercisable 7 years  
Aggregate Intrinsic Value, Outstanding $ 10,937 $ 31,239
Aggregate Intrinsic Value, Vested and expected to vest 10,937  
Aggregate Intrinsic Value, Vested and exercisable $ 10,348