Collaboration Revenue - Additional Information (Details) - USD ($) $ in Thousands	3 Months Ended		6 Months Ended
	Jun. 30, 2022	Jun. 30, 2021	Jun. 30, 2022	Jun. 30, 2021	Dec. 31, 2021
Disaggregation Of Revenue [Line Items]
Collaboration revenue		$ 60,391		$ 126,376
Research and development	$ 19,858	39,803	$ 49,491	66,375
Accrued expenses and other current liabilities	10,492		10,492		$ 52,152
Accounts payable	13,885		13,885		4,534
Roche License Agreement
Disaggregation Of Revenue [Line Items]
Collaboration revenue		60,391		126,376
Costs reimbursed amount	0	2,478	845	5,897
Research and development	0	$ 23,212	9,578	$ 37,729
Accrued expenses and other current liabilities					$ 10,417
Accounts payable	$ 8,733		$ 8,733