Exhibit 24.1

POWER OF ATTORNEY

Each of the undersigned, hereby constitutes and appoints each of Blaise Coleman, Mark T. Bradley, Matthew J. Maletta and Brian Morrissey to be his or her true and lawful attorneys-in-fact and agents, with full power of each to act alone, and to sign for the undersigned and in each of their respective names in any and all capacities stated below, this Annual Report on Form 10-K (and any amendments hereto) and to file the same, with exhibits hereto and thereto and other documents in connection herewith and therewith, with the Securities and Exchange Commission, hereby ratifying and confirming all that each of said attorneys-in-fact, or his or her substitute or substitutes, may do or cause to be done by virtue hereof.

Pursuant to the requirements of the Securities Exchange Act of 1934, this Power of Attorney has been signed by the following persons in the capacities and on the dates indicated.

Signature	Title	Date
/s/ Mark G. Barberio	Chairman and Director	March 3, 2023
Mark G. Barberio
/s/ Jennifer M. Chao	Director	March 3, 2023
Jennifer M. Chao
/s/ Shane M. Cooke	Director	March 3, 2023
Shane M. Cooke
/s/ Nancy J. Hutson, Ph.D.	Director	March 3, 2023
Nancy J. Hutson, Ph.D.
/s/ Michael Hyatt	Director	March 3, 2023
Michael Hyatt
/s/ William P. Montague	Director	March 3, 2023
William P. Montague
/s/ M. Christine Smith, Ph.D.	Director	March 3, 2023
M. Christine Smith, Ph.D.