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Other (Income) Expense, Net (Details) - USD ($)
$ in Thousands
3 Months Ended 12 Months Ended
Sep. 30, 2015
Jun. 30, 2015
Mar. 31, 2015
Dec. 31, 2016
Dec. 31, 2015
Dec. 31, 2014
Component of Operating Income [Abstract]            
Net gain on sale of certain early-stage drug discovery and development assets       $ 0 $ 0 $ (5,200)
Foreign currency loss (gain), net       2,991 (23,058) (10,054)
Equity (earnings) loss from unconsolidated subsidiaries, net       (1,190) 3,217 (8,325)
Other-than-temporary impairment of equity investment   $ 18,900   0 18,869 0
Legal settlement       0 (12,500) 0
Costs associated with unused financing commitments $ 64,300 $ 2,300 $ 11,800 0 78,352 0
Other miscellaneous, net       (2,139) (1,189) (8,745)
Other (income) expense, net       $ (338) $ 63,691 $ (32,324)