<?xml version="1.0"?>
<ownershipDocument>

    <schemaVersion>X0306</schemaVersion>

    <documentType>4</documentType>

    <periodOfReport>2021-11-29</periodOfReport>

    <issuer>
        <issuerCik>0001592386</issuerCik>
        <issuerName>Virtu Financial, Inc.</issuerName>
        <issuerTradingSymbol>VIRT</issuerTradingSymbol>
    </issuer>

    <reportingOwner>
        <reportingOwnerId>
            <rptOwnerCik>0000936828</rptOwnerCik>
            <rptOwnerName>GIC Private Ltd</rptOwnerName>
        </reportingOwnerId>
        <reportingOwnerAddress>
            <rptOwnerStreet1>168 ROBINSON ROAD</rptOwnerStreet1>
            <rptOwnerStreet2>#37-01 CAPITAL TOWER</rptOwnerStreet2>
            <rptOwnerCity>SINGAPORE</rptOwnerCity>
            <rptOwnerState>U0</rptOwnerState>
            <rptOwnerZipCode>068912</rptOwnerZipCode>
            <rptOwnerStateDescription>SINGAPORE</rptOwnerStateDescription>
        </reportingOwnerAddress>
        <reportingOwnerRelationship>
            <isTenPercentOwner>true</isTenPercentOwner>
        </reportingOwnerRelationship>
    </reportingOwner>

    <reportingOwner>
        <reportingOwnerId>
            <rptOwnerCik>0001619744</rptOwnerCik>
            <rptOwnerName>Coral Blue Investment Pte. Ltd.</rptOwnerName>
        </reportingOwnerId>
        <reportingOwnerAddress>
            <rptOwnerStreet1>168 ROBINSON ROAD</rptOwnerStreet1>
            <rptOwnerStreet2>#37-01 CAPITAL TOWER</rptOwnerStreet2>
            <rptOwnerCity>SINGAPORE</rptOwnerCity>
            <rptOwnerState>U0</rptOwnerState>
            <rptOwnerZipCode>068912</rptOwnerZipCode>
            <rptOwnerStateDescription>SINGAPORE</rptOwnerStateDescription>
        </reportingOwnerAddress>
        <reportingOwnerRelationship>
            <isTenPercentOwner>true</isTenPercentOwner>
        </reportingOwnerRelationship>
    </reportingOwner>

    <nonDerivativeTable>
        <nonDerivativeTransaction>
            <securityTitle>
                <value>Common Stock</value>
            </securityTitle>
            <transactionDate>
                <value>2021-11-29</value>
            </transactionDate>
            <transactionCoding>
                <transactionFormType>4</transactionFormType>
                <transactionCode>S</transactionCode>
                <equitySwapInvolved>0</equitySwapInvolved>
            </transactionCoding>
            <transactionAmounts>
                <transactionShares>
                    <value>1403509</value>
                </transactionShares>
                <transactionPricePerShare>
                    <value>28.5</value>
                </transactionPricePerShare>
                <transactionAcquiredDisposedCode>
                    <value>D</value>
                </transactionAcquiredDisposedCode>
            </transactionAmounts>
            <postTransactionAmounts>
                <sharesOwnedFollowingTransaction>
                    <value>16008206</value>
                </sharesOwnedFollowingTransaction>
            </postTransactionAmounts>
            <ownershipNature>
                <directOrIndirectOwnership>
                    <value>D</value>
                    <footnoteId id="F1"/>
                    <footnoteId id="F2"/>
                </directOrIndirectOwnership>
            </ownershipNature>
        </nonDerivativeTransaction>
    </nonDerivativeTable>

    <footnotes>
        <footnote id="F1">These securities are owned directly by Coral Blue Investments Pte. Ltd. (&quot;Coral Blue&quot;). Coral Blue shares the power to vote and the power to dispose of these securities with GIC Private Ltd. (&quot;GIC,&quot; and with Coral Blue, each a &quot;Reporting Person&quot;).</footnote>
        <footnote id="F2">Each Reporting Person disclaims beneficial ownership of the securities except to the extent of its pecuniary interest therein, and this report shall not be deemed an admission that such Reporting Person is the beneficial owner of the shares for purposes of Section 16 of the Securities Exchange Act of 1934, as amended, or for any other purpose.</footnote>
    </footnotes>

    <ownerSignature>
        <signatureName>GIC Private Ltd, By: /s/ Celine Loh Sze Ling and Diane Liang, Senior Vice Presidents</signatureName>
        <signatureDate>2021-12-01</signatureDate>
    </ownerSignature>

    <ownerSignature>
        <signatureName>Coral Blue Investment Pte Ltd., By: /s/ Arjun Khullar, Director</signatureName>
        <signatureDate>2021-12-01</signatureDate>
    </ownerSignature>
</ownershipDocument>
